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The protein encoded by BPIFB1 may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. Additionally we are shipping BPI Fold Containing Family B, Member 1 Antibodies (44) and many more products for this protein.
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Human BPIFB1 Protein expressed in Human - ABIN2724881
Shin, Uddin, Citorik, Wang, Della Pelle, Kradin, Bingle, Bingle, Camilli, Bhuiyan, Shirin, Ryan, Calderwood, Finberg, Qadri, Larocque, Harris: LPLUNC1 modulates innate immune responses to Vibrio cholerae. in The Journal of infectious diseases 2011
The G allele of rs1078761 may be detrimental to lung function in cystic fibrosis (show S100A8 Proteins) owing to decreased levels of BPIFA1 (show BPIFA1 Proteins) and BPIFB1.
higher sputum concentrations of BPIFB1 were associated with changes of lung function over time, especially in current smokers with chronic obstructive pulmonary disease. BPIFB1 may be involved in the pathogenesis of smoking-related lung diseases.
Autoimmunity targeting the lung-specific antigen BPIFB1 may contribute to the pathogenesis of interstitial lung disease.
Results suggest that LPLUNC1 can inhibit inflammation and nasopharyngeal carcinoma (NPC (show NPC1 Proteins)) growth by downregulating the Stat3 (show STAT3 Proteins) pathway.
LPLUNC1 delays nasopharyngeal carcinoma cell growth by inhibiting the MAP Kinase (show MAPK1 Proteins) and cyclin D1 (show CCND1 Proteins)/E2F (show E2F1 Proteins) pathways.
It was shown that there was a significant increase in LPLUNC1 in the airways of patients with cystic fibrosis (show S100A8 Proteins), but it is unclear if this increase influences the development of lung disease.
These results demonstrate that LPLUNC1 is expressed in Paneth cells and likely plays a role in modulating host inflammatory responses to Vibrio cholerae infection.
LPLUNC1 is an abundant, secreted product of goblet cells and minor mucosal glands of the respiratory tract and oral cavity and suggest that the protein functions in the complex milieu that protects the mucosal surfaces in these locations.
LPLUNC1 is found to be down-expressed in 33 of 48 nasopharyngeal carcinoma biopsies.
We found a significant association of cholera with a marker in the promoter region of LPLUNC1 (rs11906665), a member of a family of evolutionarily conserved innate immunity proteins
CETP (show CETP Proteins) inhibitor torcetrapib promotes reverse cholesterol transport in obese insulin (show INS Proteins)-resistant CETP (show CETP Proteins)-ApoB100 (show APOB Proteins) transgenic mice
a novel gene LPlunc1, a member of BPI (show BPI Proteins)/PLUNC (show BPIFA1 Proteins) gene superfamily, which is asymmetrically expressed in the developing mouse node [LPlunc1 protein]
The protein encoded by this gene may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. The encoded protein is secreted and is a member of the BPI/LBP/PLUNC protein superfamily. This gene is found with other members of the superfamily in a cluster on chromosome 20.
BPI fold-containing family B member 1
, long palate, lung and nasal epithelium carcinoma associated 1
, long palate, lung and nasal epithelium carcinoma-associated protein 1
, von Ebner minor salivary gland protein
, von Ebner minor salivary protein
, fold containing family B, member 1