BPIFB1 Protein (His tag)

Catalog No. ABIN7194423

Product Details

Target: BPIFB1 (BPI Fold Containing Family B, Member 1 (BPIFB1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This BPIFB1 protein is labelled with His tag.

Purpose: Recombinant Human BPIFB1/LPLUNC1 Protein (His Tag)

Sequence: Met 1-Gln484

Characteristics: A DNA sequence encoding the human BPIFB1 (AAH08429.1) (Met1-Gln484) was expressed with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: BPIFB1 (BPI Fold Containing Family B, Member 1 (BPIFB1))

Alternative Name: BPIFB1/LPLUNC1 (BPIFB1 Products)

Synonyms: C20orf114 Protein, LPLUNC1 Protein, Lplunc1 Protein, C13H20orf114 Protein, RGD1563047 Protein, BPI fold containing family B member 1 Protein, BPI fold containing family B, member 1 Protein, BPIFB1 Protein, Bpifb1 Protein

Background:

Background: BPIFB1, also known as LPLUNC1, belongs to the BPI/LBP/Plunc superfamily, plunc family. BPIFB1 may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. BPIFB1 is expressed in the upper respiratory tract and oral cavity, which may function in host defence. The expression of BPIF proteins is associated with CF lung disease in humans and mice. It is unclear if this elevation of protein production, which results from phenotypic alteration of the cells within the diseased epithelium, plays a role in the pathogenesis of the disease. BPIFB1 is an abundant, secreted product of goblet cells and minor mucosal glands of the respiratory tract and oral cavity and suggest that the protein functions in the complex milieu that protects the mucosal surfaces in these locations.

Synonym: C20orf114,LPLUNC1

Molecular Weight: 51.7 kDa