anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) Antibodies

The protein encoded by BAP1 localizes to the nucleus and it interacts with the RING finger domain of the breast cancer 1, early onset protein (BRCA1). Additionally we are shipping BAP1 Proteins (7) and BAP1 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BAP1 104416 Q99PU7
BAP1 8314 Q92560
BAP1 306257 D3ZHS6
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-BAP1 Antibodies at antibodies-online.com

Showing 10 out of 127 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, WB 0.1 mg Log in to see 6 to 8 Days
$313.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of BAP1 Antibody (N-term) (ABIN388948) in mouse testis lysates (35 µg/lane). BAP1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated FACS, WB Detection of BAP1 in HeLa WCE using ABIN258775 (2ug/ml). Flow Cytometry: BAP1 Antibody (1G8) [ABIN2587751] - Intracellular flow cytometric staining of 1 x 10^6 CHO (A) and HEK-293 (B) cells using BAP1 antibody (dark blue). Isotype control shown in orange. An antibody concentration of 1 ug/1x10^6 cells was used. 0.1 mL Log in to see 7 to 9 Days
$444.19
Details
Human Mouse Un-conjugated WB Anti-BAP1 antibody (monoclonal), Western blotting Lane: MCF-7 Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of BAP1 staining in Hela cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody i Immunohistochemical analysis of BAP1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated wit 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated WB The anti-BAP1 Pab (ABIN388949) is used in Western blot to detect BAP1 in SK-BR-3 cell lysate. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat testis labeled with Rabbit Anti Phospho-BAP1(Ser592) Polyclonal Antibody, Unconjugated (ABIN683413) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human breast carcinoma labeled with Rabbit Anti Phospho-BAP1(Ser592) Polyclonal Antibody, Unconjugated (ABIN683413) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$328.90
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details

BAP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
,
,
, , , , ,
Human , , , ,
,
,
, , , , , , , , , , , , , , , , , , ,
Rat (Rattus) , ,


, , , , , , , , , , , , ,

Top referenced anti-BAP1 Antibodies

  1. Human Monoclonal BAP1 Primary Antibody for FACS, WB - ABIN258775 : Harbour, Onken, Roberson, Duan, Cao, Worley, Council, Matatall, Helms, Bowcock: Frequent mutation of BAP1 in metastasizing uveal melanomas. in Science (New York, N.Y.) 2010 (PubMed)

  2. Human Polyclonal BAP1 Primary Antibody for IHC (p), WB - ABIN388948 : Abdel-Rahman, Pilarski, Cebulla, Massengill, Christopher, Boru, Hovland, Davidorf: Germline BAP1 mutation predisposes to uveal melanoma, lung adenocarcinoma, meningioma, and other cancers. in Journal of medical genetics 2011 (PubMed)

More Antibodies against BAP1 Interaction Partners

Mouse (Murine) BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) interaction partners

  1. Bap1 as a metabolic regulator in liver and pancreas.

  2. the interaction between nephrin and MAGI-1 regulates Rap1 activation in podocytes to maintain long term slit diaphragm structure

  3. BAP1(+/-) mice exposed to low-dose asbestos fibers showed an altered peritoneal inflammatory response and higher levels of pro-tumorigenic alternatively polarized M2 macrophages, and lower cytokine levels. They had a higher incidence of mesothelioma.

  4. Bap1 loss led to a fully penetrant myeloproliferative disease with splenomegaly, leukocytosis, anemia and progenitor expansion via alterations in histone methylation and gene expression.

  5. INO80 (show INO80 Antibodies) is stabilized and targeted to replication forks by BAP1 during normal DNA synthesis but downregulated in BAP1 defective cancer cells

  6. Both Vhl (show VHL Antibodies) and Bap1 are required for kidney function. Inactivation of Bap1 in neprhon progenitor cells causes renal failure earlier than Vhl (show VHL Antibodies) inactivation. Bap1 is also a stronger tumor suppressor gene than Vhl (show VHL Antibodies) in the kidney.

  7. Drawing parallels to human disease, these unbiased genetic findings indicate that BAP1 mutation carriers are predisposed to the tumorigenic effects of asbestos and suggest that high penetrance of mesothelioma requires such environmental exposure.

  8. Cx32 (show GJB1 Antibodies) expression is in part related to induction of tight junctions through modulation of Magi1 (show CNKSR3 Antibodies) expression in an immortalized hepatic cell line.

  9. ARIP1 (show MAGI2 Antibodies) and ARIP2 (show SYNJ2BP Antibodies) are co-expressed in some nerve cells and their biological activities are distinct.

  10. results identify a potent tumor suppressor function for BAP1 in myeloid neoplasia; propose that BAP1 forms a core complex with HCF-1 (show HCFC1 Antibodies) and OGT (show OGT Antibodies) that can differentially recruit additional histone-modifying enzymes to regulate gene expression and preserve norm

Human BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) interaction partners

  1. Although there have been reports of sarcomas and meningiomas in patients affected with BAP1 (show RNF2 Antibodies) mutations, to our knowledge malignant peripheral nerve sheath tumors in this patient population have not been previously reported. We report a case of malignant peripheral nerve sheath tumor in a patient affected by a BAP1 (show RNF2 Antibodies) mutation.

  2. Low BAP1 (show RNF2 Antibodies) expression is associated with lung cancer progression.

  3. Study shows that the tumor suppressor gene breast cancer [BRCA]1-associated protein 1 (BAP1 (show RNF2 Antibodies)) is inactivated in 6 high-grade, rhabdoid meningiomas. In addition to patients with somatic BAP1 (show RNF2 Antibodies) loss, 2 patients carried germline mutations, indicating that such meningiomas can arise as part of the BAP1 (show RNF2 Antibodies) cancer predisposition syndrome.

  4. Nine of the 32 (28.1%) iCCA (show PRRT2 Antibodies) patients had gene mutations at chromosome 3p, totaling 11 mutations across five genes. Those included five (15.6%) BAP1 (show RNF2 Antibodies) mutations, two each (6.3%) of CACNA2D3 (show CACNA2D3 Antibodies) and RASSF1 (show RASSF1 Antibodies) mutations, and one each (3.1%) of ATG7 (show ATG7 Antibodies) and PLCD1 (show PLCD1 Antibodies) mutations. Six (18.8%) cases had concurrent loss of chromosome 3p and gene mutations.

  5. BAP1 (show RNF2 Antibodies) mutation, Copy Number Loss, and/or Loss of Protein Expression is associated with Malignant Peritoneal Mesotheliomas.

  6. BAP1 (show RNF2 Antibodies) regulates IP3R3 (show ITPR3 Antibodies)-mediated Ca(2 (show CA2 Antibodies)+) flux to mitochondria suppressing cell transformation

  7. Loss of BAP1 (show RNF2 Antibodies) expression is associated with lung adenocarcinoma.

  8. Our data confirm the established role of BAP1 (show RNF2 Antibodies) as a tumor suppressor protein (show TP53 Antibodies) and is the first report where BAP1 (show RNF2 Antibodies) has been studied in pT1 (show ZNF77 Antibodies) clear cell renal cell carcinomas

  9. Important role of BAP1 (show RNF2 Antibodies) in the survival of osteosarcoma cells.

  10. Loss of BAP1 (show RNF2 Antibodies) expression is a rare event in non-small cell lung cancer.

BAP1 Antigen Profile

Protein Summary

The protein encoded by this gene localizes to the nucleus and it interacts with the RING finger domain of the breast cancer 1, early onset protein (BRCA1). This gene is thought to be a tumor suppressor gene that functions in the BRCA1 growth control pathway. There are multiple polyadenylation sites found in this gene.

Gene names and symbols associated with BAP1

  • Brca1 associated protein 1 (Bap1) antibody
  • BRCA1 associated protein 1 (BAP1) antibody
  • BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) (bap1) antibody
  • BRCA1 associated protein 1 L homeolog (bap1.L) antibody
  • membrane associated guanylate kinase, WW and PDZ domain containing 1 (Magi1) antibody
  • 2300006C11Rik antibody
  • AA989761 antibody
  • AIP3 antibody
  • AW553466 antibody
  • Baiap1 antibody
  • BAIAP3 antibody
  • BAP1 antibody
  • Gukmi1 antibody
  • hucep-6 antibody
  • hucep-13 antibody
  • Magi-1 antibody
  • MAGI1c antibody
  • mKIAA0272 antibody
  • mKIAA4129 antibody
  • si:dkey-42i9.9 antibody
  • TNRC19 antibody
  • uch-x4 antibody
  • uchl2 antibody
  • WWP3 antibody

Protein level used designations for BAP1

BRCA1-associated protein 1 , ubiquitin C-terminal hydrolase X4 , ubiquitin carboxyl-terminal hydrolase BAP1 , cerebral protein 6 , cerebral protein-13 , Brca1 associated protein 1 , BAI1-associated protein 3 , ubiquitin carboxy-terminal hydrolase , BAI1-associated protein 1 , BAP-1 , guanylate kinase membrane-associated inverted 1 , membrane-associated guanylate kinase inverted 1 , membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

GENE ID SPECIES
104416 Mus musculus
8314 Homo sapiens
484737 Canis lupus familiaris
306257 Rattus norvegicus
100124510 Bos taurus
415944 Gallus gallus
558885 Danio rerio
734438 Xenopus laevis
14924 Mus musculus
Selected quality suppliers for anti-BAP1 (BAP1) Antibodies
Did you look for something else?