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Basic Helix-Loop-Helix Family, Member E22 Proteins (BHLHE22)

BHLHE22 belongs to the basic helix-loop-helix (bHLH) family of transcription factors that regulate cell fate determination, proliferation, and differentiation. Additionally we are shipping BHLHE22 Antibodies (42) and BHLHE22 Kits (28) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BHLHE22 27319 Q8NFJ8
BHLHE22 59058 Q8C6A8
Rat BHLHE22 BHLHE22 365748  
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Top BHLHE22 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,784.83
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Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,830.67
Details
Yeast Mesocricetus auratus His tag   1 mg Log in to see 56 to 66 Days
$2,999.33
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BHLHE22 Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Mouse (Murine)

More Proteins for Basic Helix-Loop-Helix Family, Member E22 (BHLHE22) Interaction Partners

Zebrafish Basic Helix-Loop-Helix Family, Member E22 (BHLHE22) interaction partners

  1. These observations suggest a different regulatory mechanism on bhlhe22 expression by smarca4 and irx7

  2. atoh1.2 and beta3.1 are transcribed in distinct precursors.

Human Basic Helix-Loop-Helix Family, Member E22 (BHLHE22) interaction partners

  1. Segregates with Duane syndrome. Brain-specific expression with the highest abundance in the cerebellum.

Mouse (Murine) Basic Helix-Loop-Helix Family, Member E22 (BHLHE22) interaction partners

  1. hypothesis that neuropathic itch in BHLHB5-deficient animals can be treated by restoring inhibitory controls through spinal cord transplantation and integration of precursors of inhibitory interneurons derived from embryonic medial ganglionic eminence

  2. Bhlhb5 is broadly expressed throughout retinogenesis, and is required for the subtype development of amacrine and bipolar cells.

  3. These findings suggest that Prdm8 is an obligate partner of Bhlhb5, forming a repressor complex that directs neural circuit assembly in part through the precise regulation of Cadherin-11.

  4. Atonal-related transcription factor Bhlhb5 is required for the survival of a specific population of inhibitory interneurons that regulate pruritis, and provide evidence that the loss of inhibitory synaptic input results in abnormal itch.

  5. Mouse Bhlhb5 can strongly repress a human PAX6 promoter. A single exon encodes a 355-amino-acid bHLH protein.

  6. Localization of Bhlhb5 mRNA expression in the central nervous system and sensory organs of the mouse embryo.

  7. The results reveal that a bHLH transcription factor (show MSGN1 Proteins) cascade is involved in regulating retinal cell differentiation and imply that Bhlhb5 functions downstream of retinogenic factors to specify bipolar and amacrine subtypes.

  8. These results show Bhlhb5's function as an area-specific transcription factor that regulates the postmitotic acquisition of area identities and elucidate the genetic hierarchy between progenitors and postmitotic neurons driving neocortical arealization.

BHLHE22 Protein Profile

Protein Summary

BHLHE22 belongs to the basic helix-loop-helix (bHLH) family of transcription factors that regulate cell fate determination, proliferation, and differentiation. These proteins function as dimers and bind to an E-box DNA sequence (CANNTG). BHLHE22 is expressed exclusively in the central nervous system and retina (Xu et al., 2002

Gene names and symbols associated with BHLHE22

  • basic helix-loop-helix domain containing, class B, 5 (bhlhb5)
  • basic helix-loop-helix domain containing, class B, 5 (LOC100350894)
  • basic helix-loop-helix family, member e22 (BHLHE22)
  • basic helix-loop-helix family, member e22 (bhlhe22)
  • basic helix-loop-helix family, member e22 (Bhlhe22)
  • bHLH transcription factor beta3 (BETA3)
  • Beta3 protein
  • Beta3.1 protein
  • Bhlhb5 protein
  • BHLHE22 protein
  • CAGL85 protein
  • MGC145865 protein
  • TNRC20 protein
  • wu:fq25e11 protein
  • zgc:64225 protein

Protein level used designations for BHLHE22

basic helix-loop-helix domain containing, class B, 5 , basic helix-loop-helix family, member e22 , Beta3a , class E basic helix-loop-helix protein 22 , class B basic helix-loop-helix protein 5 , trinucleotide repeat containing 20 , trinucleotide repeat-containing gene 20 protein , basic helix-loop-helix (bHLH) gene, class B, beta3 , basic helix-loop-helix domain containing, class B5 , bHLHb5 , bHLHe22 , neuroB

GENE ID SPECIES
780395 Xenopus (Silurana) tropicalis
100350894 Oryctolagus cuniculus
701485 Macaca mulatta
393930 Danio rerio
27319 Homo sapiens
59058 Mus musculus
365748 Rattus norvegicus
101112909 Ovis aries
395164 Gallus gallus
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