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May play a role in sperm capacitation..
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Results show that the human epididymal BSPH1 shares many biochemical and functional characteristics with BSP (show KLK6 Proteins) proteins secreted by seminal vesicles of ungulates, and behaves similarly to its murine epididymal orthologue BSPH1.
BSPH1 accumulates in inclusion bodies when expressed with an N-terminal hexahistidine tag in BL21 (DE3) Escherichia coli cells, and recombinant protein bound phosphatidylcholine (show SGMS2 Proteins) liposomes, low-density lipoproteins and human sperm.
Both native BSPH1 and recombinant-BSPH1 were detected on the head and the midpiece region of sperm, although a stronger signal was detected on the midpiece region when sperm were incubated in a capacitating media.
Sperm-binding fibronectin (show FN1 Proteins) type II-module proteins are genetically linked and functionally related.
May play a role in sperm capacitation.
binder of sperm 1
, bovine seminal plasma protein homolog 1
, bovine seminal plasma protein-like 1
, epididymal sperm binding protein 2