You are viewing an incomplete version of our website. Please click to reload the website as full version.

Bleomycin Hydrolase Proteins (BLMH)

Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution\; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. Additionally we are shipping BLMH Antibodies (85) and BLMH Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BLMH 104184 Q8R016
BLMH 287552  
BLMH 642 Q13867
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top BLMH Proteins at antibodies-online.com

Showing 10 out of 23 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 10 μg Log in to see 16 Days
$250.80
Details
HOST_Escherichia coli (E. coli) Mouse His tag 10 μg Log in to see 16 Days
$250.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 2 to 3 Days
$383.25
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag,S tag 100 μg Log in to see 11 to 13 Days
$721.60
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$2,724.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,274.33
Details

BLMH Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
,
Rat (Rattus) ,
,
Human ,
,

Top referenced BLMH Proteins

  1. Human BLMH Protein expressed in Escherichia coli (E. coli) - ABIN2004229 : Montoya, Ferrell, Lazo: Genomic structure and genetic mapping of the human neutral cysteine protease bleomycin hydrolase. in Cancer research 1997 (PubMed)
    Show all 2 references for ABIN2004229

  2. Human BLMH Protein expressed in Escherichia coli (E. coli) - ABIN667250 : Schwartz, Homanics, Hoyt, Klein, Abernethy, Lazo: The neutral cysteine protease bleomycin hydrolase is essential for epidermal integrity and bleomycin resistance. in Proceedings of the National Academy of Sciences of the United States of America 1999 (PubMed)
    Show all 2 references for ABIN667250

More Proteins for Bleomycin Hydrolase (BLMH) Interaction Partners

Mouse (Murine) Bleomycin Hydrolase (BLMH) interaction partners

  1. Blmh interacts with diverse cellular processes--lipoprotein, amino acid and protein, carbohydrate, and energy metabolisms, detoxification, antioxidant defenses--that are essential for normal kidney homeostasis.

  2. Bleomycin hydrolase protects against neurodegeneration associated with elevated homocysteine thiolactone levels in hyperhomocysteinemia and Alzheimer's disease.

  3. bleomycin hydrolase functions as an MHC class I epitope-processing protease

  4. BH does not play a major role either in generating or destroying class I major histocompatibility antigen (MHC)-presented peptides that bind to the MHC in living cells. These results point to redundant functions between peptidases.

Human Bleomycin Hydrolase (BLMH) interaction partners

  1. Bleomycin hydrolase downregulation in lesional skin of adult atopic dermatitis patients is independent of filaggrin (show FLG Proteins) gene mutations

  2. This study findings suggest that Blmh interacts with diverse cellular processes from energy metabolism and anti-oxidative defenses to cell cycle, cytoskeleton dynamics, and synaptic plasticity essential for normal brain homeostasis.

  3. We also detected significant association between XRCC1 (show XRCC1 Proteins), XRCC3 (show XRCC3 Proteins), and BLHX polymorphisms and a high frequency of chromosomal damage

  4. The caspase (show CASP3 Proteins)-dependent cleavage of BLH was confirmed by cleavage of partly-purified human bleomycin hydrolase with caspase-3 (show CASP3 Proteins).

  5. present study suggests that our new method can detect novel genes of interest and that BLMH is a suppressor gene in HCC (show FAM126A Proteins)

  6. This first report on BLMH carrier status in Tunisia shows o association between carrying the BLMH-G genotype and Alzheimer's disease in epsilon4 negative or positive subjects.

  7. Cysteine proteases bleomycin hydrolase and cathepsin Z (show CTSZ Proteins) mediate N-terminal proteolysis and toxicity of mutant huntingtin (show HTT Proteins).

  8. BH activity and expression were markedly decreased in AD lesional skin, suggesting a defect of the filaggrin (show FLG Proteins) degradation pathway in AD.

  9. The homozygous variant G/G of BLMH gene SNP A1450G is associated with reduced survival and higher prevalence of early relapses in TC patients treated with bleomycin-containing chemotherapy.

BLMH Protein Profile

Protein Summary

Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution\; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily.

Gene names and symbols associated with Bleomycin Hydrolase Proteins (BLMH)

  • bleomycin hydrolase (BLMH)
  • Bleomycin hydrolase (pepC)
  • bleomycin hydrolase (AaeL_AAEL008041)
  • Bleomycin hydrolase (Apre_0140)
  • Bleomycin hydrolase (Apar_0899)
  • Bleomycin hydrolase (Smon_1289)
  • Bleomycin hydrolase (Kfla_1242)
  • Bleomycin hydrolase (Snas_3912)
  • bleomycin hydrolase (BLJ_1941)
  • Bleomycin hydrolase (Olsu_1085)
  • bleomycin hydrolase (PGTDC60_0106)
  • bleomycin hydrolase (Blmh)
  • bleomycin hydrolase (blmh)
  • AI035728 protein
  • BH protein
  • BMH protein
  • wu:fb13c01 protein
  • zgc:66261 protein

Protein level used designations for Bleomycin Hydrolase Proteins (BLMH)

Bleomycin hydrolase , bleomycin hydrolase , BLM hydrolase , BH , BMH , aminopeptidase H

GENE ID SPECIES
100072223 Equus caballus
5300178 Flavobacterium psychrophilum JIP02/86
5569945 Aedes aegypti
8396891 Anaerococcus prevotii DSM 20548
8413765 Atopobium parvulum DSM 20469
8601031 Streptobacillus moniliformis DSM 12112
8717835 Kribbella flavida DSM 17836
8885112 Stackebrandtia nassauensis DSM 44728
9190601 Bifidobacterium longum subsp. longum JDM301
9499925 Olsenella uli DSM 7084
10722336 Porphyromonas gingivalis TDC60
104184 Mus musculus
287552 Rattus norvegicus
336541 Danio rerio
734349 Xenopus laevis
395996 Gallus gallus
642 Homo sapiens
480635 Canis lupus familiaris
504483 Bos taurus
100009580 Oryctolagus cuniculus
Selected quality suppliers for BLMH Proteins (BLMH)
Did you look for something else?