Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Additionally we are shipping BMP6 Antibodies (95) and BMP6 Kits (55) and many more products for this protein.
Showing 10 out of 25 products:
Human BMP6 Protein expressed in HEK-293 - ABIN2666466
Andriopoulos, Corradini, Xia, Faasse, Chen, Grgurevic, Knutson, Pietrangelo, Vukicevic, Lin, Babitt: BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism. in Nature genetics 2009
Show all 6 references for ABIN2666466
Human BMP6 Protein expressed in Escherichia coli (E. coli) - ABIN413092
Jukes, Both, Leusink, Sterk, van Blitterswijk, de Boer: Endochondral bone tissue engineering using embryonic stem cells. in Proceedings of the National Academy of Sciences of the United States of America 2008
Show all 2 references for ABIN413092
BMP6 and oxidized low-density lipoprotein independently and synergistically induced osteogenic differentiation and mineralization in vascular endothelial cells.
Identify 3 heterozygous missense mutations in BMP6 in patients with unexplained iron overload. These mutations lead to loss of signaling to SMAD (show SMAD1 Proteins) proteins and reduced hepcidin (show HAMP Proteins) production.
These results demonstrated that Hcy up-regulated hepcidin (show HAMP Proteins) expression through the BMP6/SMAD (show SMAD1 Proteins) pathway, suggesting a novel mechanism underlying the hyperhomocysteinemia-associated perturbation of iron homeostasis.
demonstrate that BMP6 is associated with radiographic severity in AS, supporting the role wingless-type like/BMP pathway on radiographic progression in AS
These observations imply that crosstalk between the VEGF (show VEGFA Proteins) and BMP-6 signaling pathways enhances osteogenic differentiation of MSCs.
In vitro analysis revealed that recombinant BMP6 inhibited the activation of hepatic stellate cells (HSCs) and reduced proinflammatory and profibrogenic gene expression in already activated HSCs
CpG island methylation of BMP6 is found in high frequency in CRC (show CALR Proteins) and this epigenetic event is associated with suppressed protein expression in the tumor tissue.
determined whether BMP-2 (show BMP2 Proteins), -6, and -7 differentially regulate the proliferation, mineralization, and mRNA expression of bone/mineralized tissue associated genes of human periodontal ligament stem cells obtained from periodontal ligament tissue
BMP-6 attracted neutrophils and controlled the regulation of the neutrophils in the ovary.
Data indicated that hypermethylation modifications contributed to the regulation of BMP6 and induced an epithelial-to-mesenchymal transition phenotype of breast cancer during the acquisition of drug resistance.
Report temporal regulation of BMP6 mRNA expression in the oocyte, granulosa and theca cells of developing preovulatory follicles in the pig.
In Bmp6-/- mice, iron activated endogenous compensatory mechanisms of other BMPs that were not sufficient for preventing hemochromatosis (show HFE Proteins) and bone loss.
BMP6 expression levels may have potential as predictive markers for the progression of non-alcoholic liver disease.
The expression of BMP6 in periodontal ligaments may contribute to interaction between the tooth and bone during the eruption and anchoring process.
BMP-6 secreted by prostate cancer cells induces IL-6 (show IL6 Proteins) expression in macrophages; IL-6 (show IL6 Proteins), in turn, stimulates the neuroendocrine differentiation of prostate cancer cells.
these data highlight a therapeutically innovative role for BMP6 by providing a means to enhance the amount of myogenic lineage derived brown fat.
These results are consistent with novel mechanisms for regulating Bmp6 and Hamp1 (show HAMP Proteins) expression.
Prostate cancer-derived BMP-6 stimulates tumor-associated macrophages to produce IL-1a (show IL1A Proteins) through a crosstalk between Smad1 (show SMAD1 Proteins) and NF-kB1 (show NFKB1 Proteins); IL-1a (show IL1A Proteins), in turn, promotes angiogenesis and prostate cancer growth.
In addition to identifying BMP-6 expression in association with xerostomia and xerophthalmia in primary SS, results suggest that BMP-6-induced exocrine dysfunction in SS is independent of autoantibodies and immune activation associated with the disease.
BMP-6 maintains epithelial polarity via intracellular signaling from basolaterally localized BMP receptors.
During ovulation induction BMP-6 plays an important role in improvement of oocyte quality and ovarian response of the aged female, possibly by regulation of ovarian inhibitor of DNA-binding proteins (Ids) and VEGF expression.
BMP-6 mRNA is increased during transition from primordial to primary/secondary follicles in the goat ovaries.
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.
bone morphogenetic protein 6
, VG-1-related protein
, Vg1-related sequence
, vegetal related growth factor (TGFB-related)
, vegetal-related (TGFB related) cytokine
, bone morphogenic protein 6