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BMP6 Protein (His tag)

BMP6 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7491177
  • Target See all BMP6 Proteins
    BMP6 (Bone Morphogenetic Protein 6 (BMP6))
    Protein Type
    Recombinant
    Origin
    • 5
    • 4
    • 2
    Human
    Source
    • 6
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This BMP6 protein is labelled with His tag.
    Purpose
    Recombinant human BMP6 protein with C-terminal 6xHis tag
    Specificity
    BMP6 (Cys21-His513) 6xHis tag
    Characteristics
    Extracellular Domain Protein
    Purity
    The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product BMP6 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    BMP6 (Bone Morphogenetic Protein 6 (BMP6))
    Alternative Name
    BMP6 (BMP6 Products)
    Synonyms
    BMP6 Protein, zgc:113595 Protein, vgr Protein, vgr-1 Protein, vgr1 Protein, VGR Protein, VGR1 Protein, D13Wsu115e Protein, Vgr1 Protein, bone morphogenetic protein 6 Protein, bone morphogenetic protein 6 S homeolog Protein, BMP6 Protein, bmp6 Protein, bmp6.S Protein, Bmp6 Protein
    Background
    VGR, VGR1
    Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016]
    Molecular Weight
    predicted molecular mass of 55.6 kDa after removal of the signal peptide. The apparent molecular mass of BMP6-His is 40-70 kDa due to glycosylation.
    UniProt
    P22004
    Pathways
    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process
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