anti-Bone Morphogenetic Protein Receptor, Type IB (BMPR1B) Antibodies

BMPR1B encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. Additionally we are shipping BMPR1B Kits (22) and BMPR1B Proteins (17) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BMPR1B 12167 P36898
BMPR1B 658 O00238
BMPR1B 310914  
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Top anti-BMPR1B Antibodies at antibodies-online.com

Showing 10 out of 182 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-BMPR1B Pab (ABIN388739) in NCI-H460 cell lysate. BMPR1B (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB BMPR1B Antibody (Center)  western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the BMPR1B antibody detected the BMPR1B protein (arrow). BMPR1B Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BMPR1B Antibody (Center) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of anti-BMPR1B Pab (ABIN388738) in NCI-H460 cell lysate. BMPR1B (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB BMPR1B Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BMPR1B Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. BMPR1B Antibody (Center) western blot analysis in U251 cell line lysates (35µg/lane).This demonstrates the BMPR1B antibody detected the BMPR1B protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse PE FACS Detection of BMPR-IB/ALK-6 in PC-3 Human Cell Line by Flow Cytometry. PC-3 human prostate cancer cell line was stained with Mouse Anti-Human BMPR-IB/ALK-6 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$320.25
Details
Human Rabbit Un-conjugated IHC (p), WB Observed bind size: 57KD Anti- BMPR1B Picoband antibody,IHC(P) IHC(P): Human Prostatic Cancer Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated WB Lane 4: Recombinant Human BMPR1B Protein 1.25ng 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of anti-BMPR1B Pab (ABIN388740) in NCI-H460 cell lysate (Lane A) and mouse heart tissue lysate (Lane B). BMPR1B (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. 400 μL Log in to see 10 to 11 Days
$324.50
Details

BMPR1B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-BMPR1B Antibodies

  1. Human Polyclonal BMPR1B Primary Antibody for IHC (p), WB - ABIN388739 : Kan, Liu, McGuire, Berger, Awatramani, Dymecki, Kessler: Dysregulation of local stem/progenitor cells as a common cellular mechanism for heterotopic ossification. in Stem cells (Dayton, Ohio) 2009 (PubMed)
    Show all 5 references for 388739

  2. Human Polyclonal BMPR1B Primary Antibody for EIA, WB - ABIN357378 : Lehmann, Seemann, Stricker, Sammar, Meyer, Süring, Majewski, Tinschert, Grzeschik, Müller, Knaus, Nürnberg, Mundlos: Mutations in bone morphogenetic protein receptor 1B cause brachydactyly type A2. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
    Show all 4 references for 357378

  3. Human Monoclonal BMPR1B Primary Antibody for FACS - ABIN4895799 : Wang, He, Zhang, Shi, Dong, Pei, Zhu: A Selective Cell Population From Dermis Strengthens Bone Regeneration. in Stem cells translational medicine 2016 (PubMed)
    Show all 2 references for 4895799

  4. Human Polyclonal BMPR1B Primary Antibody for EIA, IHC (p) - ABIN951454 : Mick, Todorov, Smalley, Hu, Loo, Todd, Biederman, Byrne, Dechairo, Guiney, McCracken, McGough, Nelson, Reiersen, Wilens, Wozniak, Neale, Faraone: Family-based genome-wide association scan of attention-deficit/hyperactivity disorder. in Journal of the American Academy of Child and Adolescent Psychiatry 2010 (PubMed)
    Show all 2 references for 951454

  5. Human Polyclonal BMPR1B Primary Antibody for WB - ABIN388738 : ten Dijke, Yamashita, Ichijo, Franzén, Laiho, Miyazono, Heldin: Characterization of type I receptors for transforming growth factor-beta and activin. in Science (New York, N.Y.) 1994 (PubMed)

  6. Human Polyclonal BMPR1B Primary Antibody for IHC (p), WB - ABIN655973 : Saetrom, Biesinger, Li, Smith, Thomas, Majzoub, Rivas, Alluin, Rossi, Krontiris, Weitzel, Daly, Benson, Kirkwood, ODwyer, Sutphen, Stewart, Johnson, Larson: A risk variant in an miR-125b binding site in BMPR1B is associated with breast cancer pathogenesis. in Cancer research 2009 (PubMed)

More Antibodies against BMPR1B Interaction Partners

Zebrafish Bone Morphogenetic Protein Receptor, Type IB (BMPR1B) interaction partners

  1. These results indicate a germ-cell-autonomous role for BMP signal transduction in germ-cell differentiation.

Mouse (Murine) Bone Morphogenetic Protein Receptor, Type IB (BMPR1B) interaction partners

  1. dermal BMPRIB+ cells possessed a similar osteogenic differentiation potential with BMSCs in a mouse model. Dermal BMPRIB+ subpopulations possessed low immunogenicity and immunosuppressive properties before and after osteogenic differentiation.

  2. BMPR1B plays distinct roles from BMPR1A and ACVR1 in maintaining bone mass and transducing BMP signaling

  3. This study demonistrated that BMP signaling has no major role in the development of excitatory and inhibitory synapses in the lateral superior olive.

  4. Local administration of adenovirus expressing siRNA-targeting BMPR-IB may be a feasible and effective therapeutic candidate to treat or prevent wear debris-associated osteolysis.

  5. Type Ib BMP receptors mediate the rate of commissural axon extension through inhibition of cofilin (show CFL1 Antibodies) activity

  6. the BMP-2 (show BMP2 Antibodies)-BMPR-IB-ODAM (show ODAM Antibodies)-MAPK (show MAPK1 Antibodies) signaling cascade has important roles in ameloblast differentiation and enamel mineralization

  7. Variation in BMPR1B is associated with dizygotic twinning.

  8. signaling through BMPR1A (show BMPR1A Antibodies);B performs at least two roles in early respiratory development: first, it promotes tracheal formation through repression of Sox2 (show SOX2 Antibodies); and second, it restricts the site of lung bud initiation.

  9. These studies support a role for a functional BMP signaling axis as a tumor suppressor pathway in the ovary, with BMPR1A (show BMPR1A Antibodies) and BMPR1B acting downstream of BMP ligands and upstream of BMP receptor (show BMPR1A Antibodies) SMADs.

  10. results indicate a requirement for BMP signaling in generating the dorsalmost neuronal lineage of the telencephalon, DG granule neurons, and in the development of the stem cell niche that makes neurons in the adult hippocampus.

Human Bone Morphogenetic Protein Receptor, Type IB (BMPR1B) interaction partners

  1. Mutations in three genes (GDF5 (show GDF5 Antibodies), NPR2 (show NPRL2 Antibodies), BMPR1B) have been reported to cause different forms of acromesomelic dysplasia

  2. Data show that protein kinase (show CDK7 Antibodies) LKB1 (show STK11 Antibodies) physically interacts with BMP type I receptors and requires Smad7 (show SMAD7 Antibodies) protein to promote downregulation of the receptor.

  3. Results show an association between age-induced depletion of the ovarian reserve and BMPR1B receptor density and suggest that the dysregulation of BMP receptor (show BMPR1A Antibodies) signalling may inhibit the normal steroidogenic differentiation required for maturation in older patients.

  4. Low expression of BMPRIB is associated with breast cancer.

  5. Two novel mutations in BMPR1B were identified in two patients with brachydactyly type A1.

  6. Using computational analyses with the COREX/BEST algorithm, the study uncovered an overall pattern connecting various regions of BMPR-1B ectodomain, including the four conserved residues in the protein-protein interface.

  7. Novel mutation in the BMPR1B gene (R486L) in a Polish family and further delineation of the phenotypic features of BMPR1B-related brachydactyly.

  8. Data found a hypomorphic BMPR1B mutation causes du Pan (show SUPT6H Antibodies) acromesomelic dysplasia

  9. Disequilibrium of BMP2 (show BMP2 Antibodies) levels in the breast stem cell niche launches epithelial transformation by overamplifying BMPR1B cell response.

  10. Disrupting the binding of miR (show MLXIP Antibodies)-125b toward BMPR1B would increase protein expression, diminishing abnormal cell proliferation as well as serum and cellular CA125 (show MUC16 Antibodies) levels

Pig (Porcine) Bone Morphogenetic Protein Receptor, Type IB (BMPR1B) interaction partners

  1. These findings provide an important role of BMPRIB in the regulation of apoptosis and steroidogenesis of porcine granulosa cells.

  2. Report temporal regulation of BMPR1B mRNA expression in the oocyte, granulosa and theca cells of developing preovulatory follicles in the pig.

  3. Polymorphisms within the BMPR1B gene are associated with reproductive performance.

BMPR1B Antigen Profile

Protein Summary

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with BMPR1B

  • bone morphogenetic protein receptor, type IB (BMPR1B) antibody
  • bone morphogenetic protein receptor, type 1B (bmpr1b) antibody
  • bone morphogenetic protein receptor, type 1bb (bmpr1bb) antibody
  • bone morphogenetic protein receptor, type IB (LOC100218713) antibody
  • bone morphogenetic protein receptor, type 1B (Bmpr1b) antibody
  • bone morphogenetic protein receptor, type 1ba (bmpr1ba) antibody
  • bone morphogenetic protein receptor, type IB (Bmpr1b) antibody
  • Acvrlk6 antibody
  • AI385617 antibody
  • ALK-6 antibody
  • Alk6 antibody
  • alk6b antibody
  • alk6tr antibody
  • AV355320 antibody
  • BMP15 antibody
  • BMPR-1B antibody
  • BMPR-IB antibody
  • bmpr1b antibody
  • BMPRIB antibody
  • BR1b antibody
  • CDw293 antibody
  • CFK-43a antibody
  • FecB antibody
  • RPK-1 antibody
  • SKR6 antibody
  • zALK-6 antibody
  • zgc:92220 antibody
  • zgc:172219 antibody

Protein level used designations for BMPR1B

BMP receptor IB , activin receptor-like kinase 6 , bone morphogenetic protein receptor type-1B , bone morphogenetic protein receptor, type IB , bone morphogenetic protein receptor type IB,b , bone morphogenetic protein receptor type-1B-like , BMP type-1B receptor , serine/threonine-protein kinase receptor R6 , alk6 , bone morphogenetic protein receptor, type 1b , BMPR-1B , serine/threonine receptor kinase , bone morphogenetic protein receptor IB , bone morphogenetic protein binding serine/threonine kinase receptor , ALK-6 , SKR6 , receptor protein kinase , bone morphogenetic protein receptor 1B

GENE ID SPECIES
443454 Ovis aries
780089 Xenopus (Silurana) tropicalis
100149664 Danio rerio
461683 Pan troglodytes
705474 Macaca mulatta
100218713 Taeniopygia guttata
100397724 Callithrix jacchus
100444576 Pongo abelii
100467049 Ailuropoda melanoleuca
12167 Mus musculus
30742 Danio rerio
658 Homo sapiens
478484 Canis lupus familiaris
407128 Bos taurus
310914 Rattus norvegicus
396030 Gallus gallus
396691 Sus scrofa
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