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anti-Bone gamma-Carboxyglutamate (Gla) Protein (BGLAP) Antibodies

Constitutes 1-2% of the total bone protein. Additionally we are shipping Osteocalcin Kits (86) and Osteocalcin Proteins (48) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BGLAP 12096 P86546
BGLAP 632 P02818
BGLAP 25295 P04640
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Top anti-Osteocalcin Antibodies at antibodies-online.com

Showing 10 out of 329 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB BGLAP Antibody (C80) western blot analysis in HepG2 cell line lysates (35µg/lane).This demonstrates the BGLAP antibody detected the BGLAP protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of Osteocalcin (arrow) using rabbit polyclonal Osteocalcin Antibody (N-term) (ABIN388727). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the BGLAP gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat Anti-Rabbit IgG at 1: 5000;  TMB staining; Read the data in Microplate Reader by 450nm Formalin-fixed and paraffin embedded mouse embryo labeled with Anti-Osteocalcin Polyclonal Antibody, Unconjugated (ABIN1385851) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Mouse Rabbit Un-conjugated IHC (p)   100 μg Log in to see 8 to 10 Days
$1,365.83
Details
Human Rabbit Un-conjugated WB BGLAP Antibody (Center) (ABIN658258) western blot analysis in NCI-H460 cell line lysates (35 µg/lane). This demonstrates the BGLAP antibody detected the BGLAP protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Mouse Un-conjugated IHC (fro), IHC (p), WB   100 μg Log in to see 8 to 10 Days
$1,035.83
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-Osteocalcin Picoband antibody,  All lanes: Anti-Osteocalcin at 0.5ug/ml WB: Recombinant Human Osteocalcin Protein 0.5ng Predicted bind size: 38KD Observed bind size: 38KD Anti-Osteocalcin Picoband antibody,  IHC(P): Human Osteosarcoma Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Cow Mouse Un-conjugated EIA   0.2 mg Log in to see 6 to 8 Days
$357.50
Details
Cow Mouse Un-conjugated EIA   0.2 mg Log in to see 6 to 8 Days
$379.50
Details

BGLAP Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Osteocalcin Antibodies

  1. Human Polyclonal Osteocalcin Primary Antibody for EIA, IHC (p) - ABIN357367 : Yamada, Ando, Niino, Shimokata: Association of polymorphisms of interleukin-6, osteocalcin, and vitamin D receptor genes, alone or in combination, with bone mineral density in community-dwelling Japanese women and men. in The Journal of clinical endocrinology and metabolism 2003 (PubMed)
    Show all 5 references for ABIN357367

  2. Human Polyclonal Osteocalcin Primary Antibody for EIA, WB - ABIN953944 : Yeap, Chubb, Flicker, McCaul, Ebeling, Beilby, Norman: Reduced serum total osteocalcin is associated with metabolic syndrome in older men via waist circumference, hyperglycemia, and triglyceride levels. in European journal of endocrinology / European Federation of Endocrine Societies 2010 (PubMed)
    Show all 3 references for ABIN953944

  3. Human Polyclonal Osteocalcin Primary Antibody for IF (p), IHC (p) - ABIN1385851 : Li, Zhou, Wang, Yang, Ding, Zhou: Controlled dual delivery of BMP-2 and dexamethasone by nanoparticle-embedded electrospun nanofibers for the efficient repair of critical-sized rat calvarial defect. in Biomaterials 2015 (PubMed)
    Show all 2 references for ABIN1385851

  4. Human Polyclonal Osteocalcin Primary Antibody for IHC (p), WB - ABIN388727 : Willis, Loewy, Charlton-Kachigian, Shao, Ornitz, Towler: Regulation of osteocalcin gene expression by a novel Ku antigen transcription factor complex. in The Journal of biological chemistry 2002 (PubMed)
    Show all 2 references for ABIN388727

  5. Mouse (Murine) Polyclonal Osteocalcin Primary Antibody for IHC (p) - ABIN199515 : Tavassol, Schumann, Lindhorst, Sinikovic, Voss, Stuehmer, Kampmann, Bormann, Carvalho, Muelhaupt, Harder, Laschke, Menger, Gellrich, Ruecker: Accelerated angiogenic host tissue response to PLGA- scaffolds by vitalization with osteoblast like cells. in Tissue engineering. Part A 2010 (PubMed)

More Antibodies against Osteocalcin Interaction Partners

Zebrafish Bone gamma-Carboxyglutamate (Gla) Protein (BGLAP) interaction partners

  1. In zebrafish, bgp and mgp (show MGP Antibodies) mRNAs were localized in all mineralized tissues during and after calcification including bone and calcified cartilage of branchial arches.

Mouse (Murine) Bone gamma-Carboxyglutamate (Gla) Protein (BGLAP) interaction partners

  1. the uncarboxylated form of osteocalcin does not trigger Akt (show AKT1 Antibodies) phosphorylation and glucose uptake by itself but promotes insulin (show INS Antibodies)-induced glucose uptake in myotubes, probably by up-regulating Akt (show AKT1 Antibodies) signaling through ERK (show EPHB2 Antibodies) activation

  2. The Twist2 (show TWIST2 Antibodies)-Cre, Osterix (show SP7 Antibodies)-Cre and osteocalcin-Cre lines to generate conditional beta1 integrin deletions, were used to investigate the role of beta1 integrins on skeletal phenotype.

  3. OCN is gamma-carboxylated by the gamma-carboxylase (GGCX (show GGCX Antibodies)) on three glutamic acid residues, a cellular process requiring reduction of vitamin K by a second enzyme, VKORC1 (show VKORC1 Antibodies).

  4. results showed an increase in the expression of Cbfa1 (show RUNX2 Antibodies) and OCN in fibroblasts and osteoblasts exposed to fluoride.

  5. Data indicate that Ca2 (show CA2 Antibodies)+ binding triggered a similar conformational transition in both gamma-carboxyglutamic acid-containing protein osteocalcin (Gla (show GLA Antibodies)-OCN) and Glu (show GCG Antibodies)-OCN from a disordered structure to a more compact/stable form.

  6. In primary adipocytes, both carboxylated and uncarboxylated osteocalcin increased basal and insulin (show INS Antibodies)-stimulated glucose transport.

  7. Taken together, these findings demonstrate that SMILE (show CREBZF Antibodies) negatively regulates osteocalcin via a direct interaction with RUNX2 (show RUNX2 Antibodies)

  8. Osteoblast-specific expression of Fra-2 (show FOSL2 Antibodies)/AP-1 (show JUN Antibodies) controls adiponectin (show ADIPOQ Antibodies) and osteocalcin expression and affects metabolism.

  9. contribution of OC-OPN (show SPP1 Antibodies) to fracture toughness is related to their presence at the extrafibrillar organic-mineral interfaces

  10. Insulin (show INS Antibodies) resistance in osteoblasts led to a decrease in circulating levels of the active form of osteocalcin, thereby decreasing insulin (show INS Antibodies) sensitivity in skeletal muscle.

Human Bone gamma-Carboxyglutamate (Gla) Protein (BGLAP) interaction partners

  1. Nonalcoholic fatty liver disease negatively associated with right-hip bone mineral density and serum osteocalcin in Korean men.

  2. The aims of this study were to evaluate OCN and sclerostin (show SOST Antibodies) levels in subjects who underwent coronary artery bypass graft (CABG) surgery compared with those in normal controls.

  3. Serum osteocalcin levels are inversely correlated with nonalcoholic fatty liver disease in postmenopausal Chinese women with normal blood glucose levels.

  4. Serum total osteocalcin level is significantly lower in 2 diabetes mellitus patients than controls.

  5. Elevated serum preptin and decreased osteocalcin concentrations, together with insulin (show INS Antibodies) resistance, are associated with obesity and overweight.

  6. gestational diabetes is not associated with osteocalcin, under-carboxylated osteocalin, osteopontin (show SPP1 Antibodies) and leptin (show LEP Antibodies) and does not correlate with insulin (show INS Antibodies) resistance.

  7. Endocrine function of osteocalcin and the cell biology events that allow osteocalcin to become a hormone. [review]

  8. Data indicate that higher osteocalcin (OC) or its undercarboxylated form (ucOC) concentration and ucOC to osteocalcin ratio (OCR) were associated with the risk of coronary calcification in men.

  9. Data suggest that a low serum osteocalcin level was an independent risk factor for abdominal obesity.

  10. Correlation between osteocalcin-positive endothelial progenitor cells and spotty calcification in patients with coronary artery disease

Cow (Bovine) Bone gamma-Carboxyglutamate (Gla) Protein (BGLAP) interaction partners

  1. Osteopontin, osteocalcin and OB-cadherin expression in Synthetic nanohydroxyapatite vs bovine hydroxyapatite cultured Osteoblastic-like cells.

  2. Data suggest that helical content of 3 Glu (show DCTN1 Antibodies)-OCN is 57% and is independent of calcium binding; 3 Glu (show DCTN1 Antibodies)-OCN contains 3 alpha-helices around a hydrophobic core; study includes first high-resolution structure of bovine 3 Glu (show DCTN1 Antibodies)-OCN using X-ray crystallography.

  3. Serum osteocalcin levels in non-periparturient Holstein dairy cows were highest in the youngest cows, decreasing with age until time of first calving. In periparturient cows, serum osteocalcin levels were higher in primiparous than in multiparous cows.

  4. Osteocalcin is released from the bone matrix during bone resorption as intact molecules and fragments; serum osteocalcin should be considered as a marker of bone turnover rather than bone formation

Osteocalcin (BGLAP) Antigen Profile

Protein Summary

Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.

Gene names and symbols associated with BGLAP

  • osteocalcin (LOC792433) antibody
  • osteocalcin (ocn) antibody
  • osteocalcin (bgp) antibody
  • osteocalcin (LOC100286409) antibody
  • osteocalcin (LOC100529177) antibody
  • osteocalcin (LOC100534506) antibody
  • bone gamma carboxyglutamate protein (Bglap) antibody
  • bone gamma-carboxyglutamate (gla) protein (BGLAP) antibody
  • bone gamma-carboxyglutamate (gla) protein (Bglap) antibody
  • bone gamma-carboxyglutamate (gla) protein (bglap) antibody
  • galactosidase, alpha (GLA) antibody
  • Bglap1 antibody
  • Bglap2 antibody
  • Bgp antibody
  • Bgpr antibody
  • Bgpra antibody
  • GLA antibody
  • LOC792433 antibody
  • LOC100286409 antibody
  • mOC-A antibody
  • OC antibody
  • OCN antibody
  • OG1 antibody
  • si:ch1073-504d15.2 antibody

Protein level used designations for BGLAP

hypothetical protein LOC792433 , osteocalcin , BGP , bone Gla protein , bone gamma carboxyglutamate protein 1 , gamma-carboxyglutamic acid-containing protein , bone gamma-carboxyglutamate (gla) protein (osteocalcin) , bone gamma-carboxyglutamate protein osteocalcin , bone Gla-protein , bone gamma-carboxyglutamate protein 2 , bone gamma-carboxyglutamic acid (Gla) protein (osteocalcin) , osteocalcin preproprotein , xBGP , DrOC1 , bgp

GENE ID SPECIES
792433 Danio rerio
100136174 Oncorhynchus mykiss
100192339 Salmo salar
100286409 Salmo salar
100529177 Oryzias latipes
100534506 Oreochromis niloticus
12096 Mus musculus
632 Homo sapiens
403762 Canis lupus familiaris
281646 Bos taurus
396348 Gallus gallus
397530 Sus scrofa
25295 Rattus norvegicus
677670 Ovis aries
100735766 Cavia porcellus
101085947 Felis catus
718296 Macaca mulatta
399370 Xenopus laevis
494531 Danio rerio
100190891 Pan troglodytes
100861188 Capra hircus
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