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Constitutes 1-2% of the total bone protein. Additionally we are shipping Osteocalcin Antibodies (352) and Osteocalcin Kits (105) and many more products for this protein.
Showing 10 out of 49 products:
Mouse (Murine) Osteocalcin Protein expressed in Escherichia coli (E. coli) - ABIN2123429
Hase, Ozeki, Hiyama, Yamaguchi, Kawai, Kondo, Nakata, Mogi: Products of dentin matrix protein-1 degradation by interleukin-1β-induced matrix metalloproteinase-3 promote proliferation of odontoblastic cells. in Bioscience trends 2015
In zebrafish, bgp and mgp (show MGP Proteins) mRNAs were localized in all mineralized tissues during and after calcification including bone and calcified cartilage of branchial arches.
the uncarboxylated form of osteocalcin does not trigger Akt (show AKT1 Proteins) phosphorylation and glucose uptake by itself but promotes insulin (show INS Proteins)-induced glucose uptake in myotubes, probably by up-regulating Akt (show AKT1 Proteins) signaling through ERK (show EPHB2 Proteins) activation
The Twist2 (show TWIST2 Proteins)-Cre, Osterix (show SP7 Proteins)-Cre and osteocalcin-Cre lines to generate conditional beta1 integrin deletions, were used to investigate the role of beta1 integrins on skeletal phenotype.
OCN is gamma-carboxylated by the gamma-carboxylase (GGCX (show GGCX Proteins)) on three glutamic acid residues, a cellular process requiring reduction of vitamin K by a second enzyme, VKORC1 (show VKORC1 Proteins).
results showed an increase in the expression of Cbfa1 (show RUNX2 Proteins) and OCN in fibroblasts and osteoblasts exposed to fluoride.
Data indicate that Ca2 (show CA2 Proteins)+ binding triggered a similar conformational transition in both gamma-carboxyglutamic acid-containing protein osteocalcin (Gla (show GLA Proteins)-OCN) and Glu (show GCG Proteins)-OCN from a disordered structure to a more compact/stable form.
In primary adipocytes, both carboxylated and uncarboxylated osteocalcin increased basal and insulin (show INS Proteins)-stimulated glucose transport.
Taken together, these findings demonstrate that SMILE (show CREBZF Proteins) negatively regulates osteocalcin via a direct interaction with RUNX2 (show RUNX2 Proteins)
Osteoblast-specific expression of Fra-2 (show FOSL2 Proteins)/AP-1 (show JUN Proteins) controls adiponectin (show ADIPOQ Proteins) and osteocalcin expression and affects metabolism.
contribution of OC-OPN (show SPP1 Proteins) to fracture toughness is related to their presence at the extrafibrillar organic-mineral interfaces
Insulin (show INS Proteins) resistance in osteoblasts led to a decrease in circulating levels of the active form of osteocalcin, thereby decreasing insulin (show INS Proteins) sensitivity in skeletal muscle.
Low serum osteocalcin concentrations are associated with type 2 diabetes.
Decreased blood concentration of Carboxylated osteocalcin is associated with metabolic complications and inflammation.
Total and undercarboxylated osteocalcin levels were significantly correlated with insulin (show INS Proteins) secretion and insulin (show INS Proteins) resistance indices, but not adiponectin (show ADIPOQ Proteins) levels, in pregnant women.
Osteocalcin and Sex Hormone Binding Globulin Compete on a Specific Binding Site of GPRC6A.
Osteocalcin plays an essential role for the maturation of mineral species and modulates osteogenic differentiation of mesenchymal stromal cells (MSCs).
Serum osteocalcin levels in pediatric obstructive sleep apnea hypopnea syndrome patients were significantly lower than normal controls before adenotonsillectomy.
the relationship between serum osteocalcin and glucose metabolism parameters in liver transplantation recipients, was examined.
Reduced plasma Osteocalcin levels are associated with cardiovascular and metabolic diseases.
An overview of osteocalcin progress.
the BMP-2 (show BMP2 Proteins)/Smad1 (show GARS Proteins)/5/RUNX2 (show RUNX2 Proteins) signaling pathway participates in the silicon-mediated induction of COL-1 and osteocalcin synth
Osteopontin, osteocalcin and OB-cadherin expression in Synthetic nanohydroxyapatite vs bovine hydroxyapatite cultured Osteoblastic-like cells.
Data suggest that helical content of 3 Glu (show DCTN1 Proteins)-OCN is 57% and is independent of calcium binding; 3 Glu (show DCTN1 Proteins)-OCN contains 3 alpha-helices around a hydrophobic core; study includes first high-resolution structure of bovine 3 Glu (show DCTN1 Proteins)-OCN using X-ray crystallography.
Serum osteocalcin levels in non-periparturient Holstein dairy cows were highest in the youngest cows, decreasing with age until time of first calving. In periparturient cows, serum osteocalcin levels were higher in primiparous than in multiparous cows.
Osteocalcin is released from the bone matrix during bone resorption as intact molecules and fragments; serum osteocalcin should be considered as a marker of bone turnover rather than bone formation
Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.
hypothetical protein LOC792433
, bone Gla protein
, bone gamma carboxyglutamate protein 1
, gamma-carboxyglutamic acid-containing protein
, bone gamma-carboxyglutamate (gla) protein (osteocalcin)
, bone gamma-carboxyglutamate protein osteocalcin
, bone Gla-protein
, bone gamma-carboxyglutamate protein 2
, bone gamma-carboxyglutamic acid (Gla) protein (osteocalcin)
, osteocalcin preproprotein