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Botulinum toxin acts by inhibiting neurotransmitter release.
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Clostridium botulinum (C. botulinum) Monoclonal BoNT/B Primary Antibody for cELISA, FACS - ABIN179725
DasGupta: Structure and biological activity of botulinum neurotoxin. in Journal de physiologie 1991
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Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that cleaves the '76-Gln-|-Phe-77' bond of synaptobrevin-2 (By similarity).
botulinum neurotoxin type B
, botulinum neurotoxin type B, BoNT/B