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BUB3 encodes a protein involved in spindle checkpoint function. Additionally we are shipping BUB3 Proteins (8) and many more products for this protein.
Showing 10 out of 99 products:
Human Monoclonal BUB3 Primary Antibody for BI, WB - ABIN968647
Martinez-Exposito, Kaplan, Copeland, Sorger: Retention of the BUB3 checkpoint protein on lagging chromosomes. in Proceedings of the National Academy of Sciences of the United States of America 1999
Show all 2 references for ABIN968647
Chicken Polyclonal BUB3 Primary Antibody for IF, WB - ABIN2787758
Vaclavicek, Bermejo, Wappenschmidt, Meindl, Sutter, Schmutzler, Kiechle, Bugert, Burwinkel, Bartram, Hemminki, Försti: Genetic variation in the major mitotic checkpoint genes does not affect familial breast cancer risk. in Breast cancer research and treatment 2007
Human Polyclonal BUB3 Primary Antibody for ICC, IF - ABIN4285582
Stadler, Hjelmare, Neumann, Jonasson, Pepperkok, Uhlén, Lundberg: Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy. in Journal of proteomics 2012
The integrity of the mitotic checkpoint complex depends on the specific recognition between BubR1 (show BUB1B Antibodies) and Bub3, for which the BubR1 (show BUB1B Antibodies) Gle2 (show RAE1 Antibodies) binding sequence motif is essential.
We show that kinetochore recruitment of BUBR1 (show BUB1B Antibodies) and BUB3 by BUB1 (show BUB1 Antibodies) is dispensable for SAC (show ADCY10 Antibodies) activation
a mutual antagonism exists between Bub3 and dynein to ensure optimal KT-MT attachments
the mechanisms of BUB3 in mitotic checkpoint signaling
Data show sequential multisite regulation of the microtubule-associated protein KNL1 (show CASC5 Antibodies)-kinase-adaptor complex BUB1 (show BUB1 Antibodies)/BUB3 interaction.
Data indicate that cell cycle protein Bub3-mediated kinetochore recruitment of BubR1 (show BUB1B Antibodies) kinase enhances mitotic checkpoint signaling.
Results suggest that these USP7 (show USP7 Antibodies)-dependent effects are mediated by decreased levels of spindle assembly checkpoint (SAC (show ADCY10 Antibodies)) component Bub3.
Mutations targeting the Bub3 interface prevent kinetochore recruitment of the SAC (show ADCY10 Antibodies) kinase Bub1 (show BUB1 Antibodies). Crucially, they also cause a checkpoint defect, showing that recognition of phosphorylated targets by Bub3 is required for checkpoint signaling
Results showed that neither variants in BUB3 nor variants in MAD2L1 (show MAD2L1 Antibodies) caused any significant effect on the risk of breast cancer
Mutations in BUB1 (show BUB1 Antibodies) and BUB3 cause mosaic variegated aneuploidy and increase the risk of colorectal cancer at a young age.
as a member of the spindle assembly checkpoint, Bub3 is required for regulation of both meiosis I and II, and is potentially involved in kinetochore-microtubule attachment in mammalian oocytes
Cenpa (show CENPA Antibodies), Cenpb (show CENPB Antibodies), and Bub3, but not Cenpc (show CENPC1 Antibodies), interacted with PARP-1 (show PARP1 Antibodies)
Haploinsufficiency of Bub3 causes a slight increase in chromosome instability but is not clearly associated with a noticeable rise in the probability of tumor formation.
subpopulation of dynein, containing the DYNLT3 (show DYNLT3 Antibodies) light chain, may be important for chromosome congression, in addition to having a role in the transport of checkpoint proteins from the kinetochore to the spindle pole
This gene encodes a protein involved in spindle checkpoint function. The encoded protein contains four WD repeat domains and has sequence similarity with the yeast BUB3 protein. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
BUB3 budding uninhibited by benzimidazoles 3 homolog
, budding uninhibited by benomyl
, budding uninhibited by benzimidazoles 3 homolog
, mitotic checkpoint component
, mitotic checkpoint protein BUB3
, WD repeat protein Bub3
, WD repeat type I transmembrane protein A72.5