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anti-C-Type Lectin Domain Family 4, Member E (CLEC4E) Antibodies

CLEC4E encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Additionally we are shipping CLEC4E Kits (13) and CLEC4E Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CLEC4E 26253 Q9ULY5
CLEC4E 56619 Q9R0Q8
CLEC4E 450223 Q67EQ1
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Top anti-CLEC4E Antibodies at antibodies-online.com

Showing 10 out of 59 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated EIA, IF, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Mouse Un-conjugated ELISA, WB CLEC4E monoclonal antibody (M08), clone 2D12. Western Blot analysis of CLEC4E expression in K-562. Western Blot detection against Immunogen (49.83 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated FACS, IHC (p), WB 100 μL Log in to see 8 to 10 Days
$529.83
Details
Human Mouse Un-conjugated IF, ELISA, WB Paraffin embedded sections of colorectal canitrocelluloseer tissue were initrocelluloseubated with anti-human MInitrocelluloseLE antibody (1:50) for 2 hours at room temperature. Antigen retrieval was performed in 0.1M sodium citrate buffer and detected using Diaminobenzidine (DAB). Cell lysates of HeLa (35 ug) were resolved by SDS-PAGE, transferred to nitrocellulose membrane and probed with anti-human MInitrocelluloseLE (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. 100 μL Log in to see 3 to 4 Days
$376.79
Details
Human Mouse Un-conjugated IF, IHC, ELISA, WB   50 μL Log in to see 11 to 16 Days
$392.86
Details
Human Mouse Un-conjugated ELISA, ICC, IF, IHC, IHC (p), WB   0.1 mL Log in to see 8 to 11 Days
$443.24
Details
Human Mouse Un-conjugated ELISA, WB   0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse PE ELISA, ICC, IF, IHC, IHC (p), WB   0.1 mL Log in to see 10 to 13 Days
$470.66
Details
Human Mouse Un-conjugated IHC (p)   100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated FACS   100 μL Log in to see 8 to 10 Days
$493.17
Details

CLEC4E Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CLEC4E Antibodies

  1. Human Monoclonal CLEC4E Primary Antibody for EIA, IF - ABIN487350 : Ishikawa, Ishikawa, Morita, Toyonaga, Yamada, Takeuchi, Kinoshita, Akira, Yoshikai, Yamasaki: Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle. in The Journal of experimental medicine 2009 (PubMed)
    Show all 3 references for ABIN487350

  2. Human Monoclonal CLEC4E Primary Antibody for ELISA, WB - ABIN565251 : Bugarcic, Hitchens, Beckhouse, Wells, Ashman, Blanchard: Human and mouse macrophage-inducible C-type lectin (Mincle) bind Candida albicans. in Glycobiology 2008 (PubMed)
    Show all 2 references for ABIN565251

More Antibodies against CLEC4E Interaction Partners

Human C-Type Lectin Domain Family 4, Member E (CLEC4E) interaction partners

  1. Induction of Mincle by Helicobacter pylori and consequent anti-inflammatory signaling denote a bacterial survival strategy.

  2. our findings identify mincle as a contributor to the inflammatory response after traumatic brain injury

  3. Data indicate that MINCLE receptor is able to mediate the response to trehalose-6,6-dimycolate (TDM) dependent on SYK (show SYK Antibodies) kinase and CARD9 (show CARD9 Antibodies) protein.

  4. mincle is a fungal receptor that can suppress antifungal immunity and, as such, is a potential therapeutic target.

  5. These results demonstrated that GroMM is a unique ligand for human Mincle that is not recognized by mouse Mincle.

  6. Results show the molecular mechanism of glycolipid recognition through C-type lectin (show MBL2 Antibodies) receptors, which may provide clues to rational design for effective adjuvants.

  7. Macrophage-inducible C-type lectin is associated with anti-cyclic citrullinated peptide antibodies-positive rheumatoid arthritis in men.

  8. Mincle is a potentially critical player in human B cell responses.

  9. Data indicate an unusual pattern of reciprocal expression of Mincle on peripheral blood monocytes or neutrophils.

  10. silencing of renal DNaseI (show DNASE1 Antibodies) gene expression initiates a cascade of inflammatory signals including activation of Toll (show TLR4 Antibodies) like receptors and Clec4e, leading to progression of both murine and human lupus nephritis

Mouse (Murine) C-Type Lectin Domain Family 4, Member E (CLEC4E) interaction partners

  1. Data show that Mincle, the inducible receptor for mycobacterial cord factor, is the key switch for the transition of macrophages from cytokine expression to high nitric oxide production.

  2. Mincle Activation and the Syk (show SYK Antibodies)/Card9 (show CARD9 Antibodies) Signaling Axis Are Central to the Development of Autoimmune Disease of the Eye

  3. work shows parallel networks of necroptosis-induced CXCL1 (show CXCL1 Antibodies) and Mincle signalling that promote macrophage-induced adaptive immune suppression and thereby enable pancreatic ductal adenocarcinoma progression

  4. The results indicate differential roles for Dectin-2 (show CLEC6A Antibodies) and Mincle in the generation of adaptive immune responses to F. pedrosoi fungal infection in mice.

  5. Mincle is essential for the activation of macrophages by trehalose glycolipids, the receptor does not play a role in the uptake of these glycolipids or of glycolipid-coated particles.

  6. These results suggest that MCL (show CLEC4D Antibodies) positively regulates Mincle expression through protein-protein interaction via its stalk region, thereby magnifying Mincle-mediated signaling.

  7. Collectively, authors show that expression of Mincle, particularly by classical dendritic cells, contributes to the control of splenic Mycobacterium bovis BCG (show SLC11A1 Antibodies) infection in mice.

  8. Trehalose 6,6'-dimycolate-induced Mincle expression is dependent on Dectin-3-mediated NF-kappaB (show NFKB1 Antibodies) activation through the CARD9 (show CARD9 Antibodies)-BCL10 (show BCL10 Antibodies)-MALT1 (show MALT1 Antibodies) complex.

  9. identify C/EBPbeta as central hub in Mincle expression and inflammatory gene induction, whereas HIF1alpha controls Nos2 expression.

  10. These results demonstrated that GroMM is a unique ligand for human Mincle that is not recognized by mouse Mincle.

Cow (Bovine) C-Type Lectin Domain Family 4, Member E (CLEC4E) interaction partners

  1. The data demonstrate how mincle bridges between the surfaces of the macrophage and the mycobacterium.

Guinea Pig C-Type Lectin Domain Family 4, Member E (CLEC4E) interaction partners

  1. the function of the guinea pig homologue of Mincle (gpMincle) and MCL (show CLEC4D Antibodies) (gpMCL). gpMincle directly bound to trehalose-6,6'-dimycolate

CLEC4E Antigen Profile

Protein Summary

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein is a downstream target of CCAAT/enhancer binding protein (C/EBP), beta (CEBPB) and may play a role in inflammation. Alternative splice variants have been described but their full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Gene names and symbols associated with CLEC4E

  • C-type lectin domain family 4, member E (CLEC4E) antibody
  • C-type lectin domain family 4, member e (Clec4e) antibody
  • C-type lectin domain family 4, member E (Clec4e) antibody
  • C-type lectin domain family 4, member E (LOC100350649) antibody
  • C86253 antibody
  • CLEC4E antibody
  • Clecsf9 antibody
  • Mincle antibody

Protein level used designations for CLEC4E

C-type lectin domain family 4, member E , C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 9 , C-type lectin domain family 4 member E , C-type lectin superfamily member 9 , macrophage-inducible C-type lectin , C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 9 , C-type lectin, superfamily member 9 , immunoreceptor

GENE ID SPECIES
611538 Canis lupus familiaris
722250 Macaca mulatta
735637 Pan troglodytes
100135686 Ovis aries
26253 Homo sapiens
56619 Mus musculus
450223 Rattus norvegicus
514797 Bos taurus
100350649 Oryctolagus cuniculus
100726838 Cavia porcellus
Selected quality suppliers for anti-CLEC4E (CLEC4E) Antibodies
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