CLEC4E antibody (AA 41-219) (FITC)

Catalog No. ABIN7146079

This anti-CLEC4E antibody is a Rabbit Polyclonal antibody detecting CLEC4E in . Suitable for Human.

Quick Overview for CLEC4E antibody (AA 41-219) (FITC) (ABIN7146079)

Target: CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLEC4E antibody is conjugated to FITC

Application: Please inquire

Product Details anti-CLEC4E Antibody (FITC)

Binding Specificity: AA 41-219

Purpose: CLEC4E Antibody, FITC conjugated

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human C-type lectin domain family 4 member E protein (41-219AA)

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CLEC4E

Target: CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))

Alternative Name: CLEC4E

Background:

Background: C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6\\\'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.

Aliases: C type lectin domain family 4 member E antibody, C type lectin superfamily member 9 antibody, C-type (calcium dependent carbohydrate recognition domain) lectin superfamily member 9 antibody, C-type lectin domain family 4 member E antibody, C-type lectin superfamily member 9 antibody, CLC4E_HUMAN antibody, CLEC 4E antibody, Clec4e antibody, CLECSF9 antibody, Macrophage inducible C type lectin antibody, Macrophage-inducible C-type lectin antibody, MINCLE antibody

UniProt: Q9ULY5