anti-CD248 Molecule, Endosialin (CD248) Antibodies

May play a role in angiogenesis or vascular function.. Additionally we are shipping CD248 Proteins (7) and CD248 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CD248 293669  
CD248 70445 Q91V98
CD248 57124 Q9HCU0
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Top anti-CD248 Antibodies at antibodies-online.com

Showing 10 out of 80 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, IHC (p), WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Alexa Fluor 647 FACS, IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Un-conjugated WB Western blot analysis of CD248 expression in HEK293T (A), NIH3T3 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Human Pancreas (formalin-fixed, paraffin-embedded) stained with CD248at 5 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Western blot analysis of TEM1 in human colon tissue lysate with TEM1 antibody at (A) 0.5 and (B) 1 µg/ml. 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 15 to 19 Days
$466.62
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 15 to 19 Days
$466.62
Details
Human Rabbit Un-conjugated WB Western blot analysis of CD248 expression in HEK293T (A), HepG2 (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details

CD248 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CD248 Antibodies

  1. Human Polyclonal CD248 Primary Antibody for IHC, ELISA - ABIN1003255 : Christian, Ahorn, Koehler, Eisenhaber, Rodi, Garin-Chesa, Park, Rettig, Lenter: Molecular cloning and characterization of endosialin, a C-type lectin-like cell surface receptor of tumor endothelium. in The Journal of biological chemistry 2001 (PubMed)
    Show all 4 references for 1003255

  2. Human Polyclonal CD248 Primary Antibody for IHC, ELISA - ABIN1003256 : Nanda, St Croix: Tumor endothelial markers: new targets for cancer therapy. in Current opinion in oncology 2003 (PubMed)
    Show all 4 references for 1003256

  3. Human Polyclonal CD248 Primary Antibody for FACS, IF (p) - ABIN917320 : Farinon, Clarimundo, Pedrazza, Gulko, Zuanazzi, Xavier, de Oliveira: Disease modifying anti-rheumatic activity of the alkaloid montanine on experimental arthritis and fibroblast-like synoviocytes. in European journal of pharmacology 2017 (PubMed)

More Antibodies against CD248 Interaction Partners

Mouse (Murine) CD248 Molecule, Endosialin (CD248) interaction partners

  1. the data demonstrate a critical role for endosialin-expressing primary tumor pericytes in mediating metastatic dissemination and identify endosialin as a promising therapeutic target in breast cancer

  2. Our data show that deletion of CD248 reduces susceptibility to liver fibrosis via an effect on PDGF (show PDGFA Antibodies) signaling.

  3. Endosialin is a potential regulator of phenotypic remodeling of vascular smooth muscle cells contributing to atherosclerosis.

  4. suggest that CD248 stromal cells have a pathogenic role in renal fibrosis

  5. We conclude that CD248 is required for PDGFRbeta-dependant capillary sprouting but not splitting angiogenesis, and identify a new role for CD248 expressed on pericytes in the early stages of physiological angiogenesis during muscle remodelling.

  6. Tem1-TT vaccination elicited CD8+ and/or CD4+ T cell responses against immunodominant TEM1 protein sequences. Prophylactic immunization of animals with Tem1-TT prevented or delayed tumor formation in several tumor models.

  7. Expression of CD248 was seen in osteoblasts, but not osteoclasts. CD248(-/-) mouse tibiae had higher bone mass and superior mechanical properties compared to WT mice. Primary osteoblasts from CD248(-/-) mice induced increased bone mineralization

  8. The multiple pathways regulated by the cytoplasmic domain of CD248 highlight its potential as a therapeutic target to treat cancer.

  9. our observations suggest that Tem1 is expressed throughout embryonic and adult development in several types of mesenchymal cells closely related to blood vessels.

  10. Tem1 have significant implications for the mechanisms underlying tumor invasiveness and for models that evaluate this process

Human CD248 Molecule, Endosialin (CD248) interaction partners

  1. the data demonstrate a critical role for endosialin-expressing primary tumor pericytes in mediating metastatic dissemination and identify endosialin as a promising therapeutic target in breast cancer

  2. Endosialin is a potential regulator of phenotypic remodeling of vascular smooth muscle cells contributing to atherosclerosis.

  3. Tumour cell endosialin expression was seen in 89% of undifferentiated pleomorphic sarcomas, 77% of adult fibrosarcomas/spindle cell sarcomas, 62% of synovial sarcomas, 51% of leiomyosarcomas and 31% of rhabdomyosarcomas.

  4. CD248 overexpression is possibly involved in the pathogenesis of IPF and it has potential as a disease severity marker.

  5. TEM1 expression in cancer-associated fibroblasts is correlated with a poor prognosis in patients with gastric cancer

  6. MORAb-004 reduced CD248 on pericytes, impaired tumor microvasculature maturation and ultimately suppressed tumor development.

  7. The authors show that endosialin, a C-type lectin (show MBL2 Antibodies), expressed in the liver exclusively by HSC (show FUT1 Antibodies) and portal fibroblasts, is upregulated in liver fibrosis in mouse and man.

  8. The genes CD248, Ephb1 (show EPHB1 Antibodies) and P2RY2 (show P2RY2 Antibodies) were detected as the top overexpressed in GC biopsies.

  9. new monoclonal antibodies described in this paper are domain-specific and represent important reagents for the study of functional contributions of extracellular endosialin domains

  10. [review] CD248 is a C-type lectin (show MBL2 Antibodies)-like domain-containing cell surface glycoprotein (show GJA8 Antibodies) that is expressed by stromal cells of proliferating tissues during embryogenesis and postnatally in tumors and inflammatory lesions.

CD248 Antigen Profile

Protein Summary

May play a role in angiogenesis or vascular function.

Gene names and symbols associated with CD248

  • CD248 molecule, endosialin (Cd248) antibody
  • CD248 antigen, endosialin (Cd248) antibody
  • CD248 molecule, endosialin (CD248) antibody
  • 2610111G01Rik antibody
  • AI842296 antibody
  • CD164L1 antibody
  • TEM1 antibody

Protein level used designations for CD248

CD164 sialomucin-like 1 , CD248 antigen, endosialin , endosialin , tumor endothelial marker 1 , 2610111G01Rik

GENE ID SPECIES
293669 Rattus norvegicus
70445 Mus musculus
57124 Homo sapiens
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