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The protein encoded by CD27 is a member of the TNF-receptor superfamily. Additionally we are shipping CD27 Antibodies (346) and CD27 Proteins (24) and many more products for this protein.
Showing 3 out of 15 products:
Human CD27 ELISA Kit for Sandwich ELISA - ABIN1889312
Salzer, Daschkey, Choo, Gombert, Santos-Valente, Ginzel, Schwendinger, Haas, Fritsch, Pickl, Förster-Waldl, Borkhardt, Boztug, Bienemann, Seidel: Combined immunodeficiency with life-threatening EBV-associated lymphoproliferative disorder in patients lacking functional CD27. in Haematologica 2013
Show all 2 references for ABIN1889312
Mouse (Murine) CD27 ELISA Kit for Sandwich ELISA - ABIN1672775
Carr, Carrasco, Thaventhiran, Bambrough, Kraman, Edwards, Al-Shamkhani, Fearon: CD27 mediates interleukin-2-independent clonal expansion of the CD8+ T cell without effector differentiation. in Proceedings of the National Academy of Sciences of the United States of America 2006
Show all 2 references for ABIN1672775
HSCs appear to maintain expression of CD27 after hematopoietic injury when Kit expression is downregulated.
Mature CD27low NK cells promote allograft survival under costimulatory blockade conditions by regulating alloreactive memory CD8+ T-cell responses in T-bet dependent manner.
identify an IL-17 (show IL17A ELISA Kits)-dependent lymphoid/myeloid cross-talk involving CD27(-) gammadelta T cells and small peritoneal macrophages that promotes ovarian tumor cell growth and thus counteracts cancer immunosurveillance
memory CD8 (show CD8A ELISA Kits) T cells, generated through priming with CD27 agonists, proliferated more extensively than did 4-1BB (show TNFRSF9 ELISA Kits)-generated memory cells, but these cells failed to persist.
the central role played by CD27/70 during secondary CD8 (show CD8A ELISA Kits)(+) T-cell activation to a peptide Ag, and identify sCD70 as an immunotherapeutic adjuvant for antitumor immunity.
under conditions of constitutive CD70 (show CD70 ELISA Kits) expression reflecting chronic immune activation, the CD27/CD70 (show CD70 ELISA Kits) system inhibits OC differentiation and favors DC differentiation
mTECs and DCs form dedicated niches in the thymic medulla, in which CD27-CD70 (show CD70 ELISA Kits) co-stimulation rescues developing Treg cells from apoptosis, subsequent to Foxp3 (show FOXP3 ELISA Kits) induction by TCR and CD28 (show CD28 ELISA Kits) signals.
The CD27 and CD70 (show CD70 ELISA Kits) costimulatory pathway inhibits effector function of T helper 17 cells and attenuates associated autoimmunity.
population of CD27(-) Th2 cells was significantly reduced by the anti-CD70 (show CD70 ELISA Kits) mAb treatment
The CD4 (show CD4 ELISA Kits)+ T-cell help signal is transmitted from APC (show APC ELISA Kits) to CD8 (show CD8A ELISA Kits)+ T-cells via CD27-CD70 (show CD70 ELISA Kits) interactions.
Novel mutations in TNFRSF7/CD27 cause EBV-associated lymphoproliferative disease/hemophagocytic lymphohistiocytosis, Hodgkin lymphoma, uveitis, and recurrent infections.
NFKB1 (show NFKB1 ELISA Kits), CD27, LAG3 (show LAG3 ELISA Kits) and IKZF3 (show IKZF3 ELISA Kits) are new susceptibility genes for psoriasis.
results provide the first evidence for differential expression of CD27 among CLL prognostic groups, suggest a role for ZAP-70 (show ZAP70 ELISA Kits) dependent signaling in CD27 induction and implicate CD27 in cell-cell interactions with the lymphoid tissue microenvironment
A lower primary CD24 (show CD24 ELISA Kits)(hi) CD27(+) CD19 (show CD19 ELISA Kits)(+) B cells may be an immunologic aspect of new-onset SLE that may be a useful tool to evaluate lupus activity and monitor the response to therapy.
Multiple layers of memory B cells to T cell- dependent antigens describe immunoglobulin IgM+ B cells representing a memory reservoir that can re-enter the germinal center, ensuring replenishment of class-switched memory CD27+ B cells.
Data indicate a unique expansion of CD27(high) plasmablasts in both the cerebrospinal fluid and periphery of transverse myelitis (TM). patients
CD27positive B cells from common variable immunodeficiency (CVID (show TNFRSF13B ELISA Kits)) patients are more sensitive than CD27negative B cells to spontaneous apoptosis and less sensitive to rescue from apoptosis; these B cells fail to differentiate to memory or plasma cells.
lack of functional CD27 predisposes towards a combined immunodeficiency associated with potentially fatal EBV-driven hemo-phagocytosis, lymphoproliferation (show FAS ELISA Kits), and lymphoma development.
The CCR7 (show CCR7 ELISA Kits)+CD45RA-CD27+CD28 (show CD28 ELISA Kits)+ central memory subset is significantly decreased in the peripheral blood CD4 (show CD4 ELISA Kits)+ T cells from rheumatoid arthritis patients.
We identified soluble CD27 as an immune modulator associated with enhanced human T cell activation
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
tumor necrosis factor receptor superfamily, member 7
, CD27 antigen
, CD27L receptor
, CD antigen 27
, T-cell activation antigen CD27
, tumor necrosis factor receptor superfamily member 7
, T cell activation antigen S152