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Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets..
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Mouse (Murine) Monoclonal CD69 Primary Antibody for FACS - ABIN135257
Karlhofer, Yokoyama: Stimulation of murine natural killer (NK) cells by a monoclonal antibody specific for the NK1.1 antigen. IL-2-activated NK cells possess additional specific stimulation pathways. in Journal of immunology (Baltimore, Md. : 1950) 1991
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Mouse (Murine) Monoclonal CD69 Primary Antibody for FACS - ABIN135255
Yokoyama, Koning, Kehn, Pereira, Stingl, Coligan, Shevach: Characterization of a cell surface-expressed disulfide-linked dimer involved in murine T cell activation. in Journal of immunology (Baltimore, Md. : 1950) 1988
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Data show that after tumor necrosis factor alpha-induced protein 8 like-2 (TIPE2 (show TNFAIP8L2 Antibodies)) gene was down-regulated, the expression of the CD69 antigen was increased, and the proliferation of T lymphocytes and the secretion of cytokines IL-2 (show IL2 Antibodies) and IFN-gamma (show IFNG Antibodies) were enhanced.
The generation of cancer-specific CD8 (show CD8A Antibodies)(+) CD69(+)-expressing lymphocytes that inhibit colon cancer growth has been described.
Maintenance of immune tolerance by Foxp3 (show FOXP3 Antibodies)+ regulatory T cells requires CD69 expression.
AIM(-/-) mice were highly susceptible to steatosis-associated HCC (show FAM126A Antibodies) development, whereas no AIM(+/+) mouse developed the disease despite comparable liver inflammation and fibrosis in response to a long-term high-fat diet.
CD69 interference with S1P1 (show S1PR1 Antibodies) function regulates peripheral T cell retention.
The NKG2A (show KLRC1 Antibodies) expression was increased in hepatic CD69-NK cells.
Report role of ZAP-70 (show ZAP70 Antibodies) kinase mutation/deletion on thymocyte-positive selection via CD69 signaling.
The early activation marker CD69 regulates the expression of chemokines and CD4 (show CD4 Antibodies) T cell accumulation in intestine.
Data indicate that CD69 is upregulated on endogenous dendritic cells (DC) upon activation.
Intron I acts as an important regulatory element of CD69 expression.
Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.
Very Early Activation Antigen
, early activation antigen CD69