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Plays a role in B-cell proliferation and differentiation.. Additionally we are shipping CD72 Antibodies (133) and CD72 Proteins (20) and many more products for this protein.
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CD72 negatively regulates mouse mast cell functions and down-regulates the expression of KIT and FcepsilonRIalpha.
CD5 (show CD5 ELISA Kits) and CD72 play a critical role in maintaining regulatory T and B cell homeostasis
These results strongly suggest that the Cd72(c) is a crucial modifier gene that regulates Fas(lpr (show FAS ELISA Kits))-induced autoimmune disease due to its reduced activity of B cell signal regulation.
Cd72 polymorphism affects susceptibility to lupus phenotypes.
Inhibitory coreceptors CD72 and CD22 (show CD22 ELISA Kits) are responsible for setting the requirement of CD40 (show CD40 ELISA Kits) signaling for survival and proliferation of antigen-stimulated spleen B cells.
results strongly suggest that the apoptosis preventing signal evoked by CD72 ligation is delivered through the pathway of NF-kappaB (show NFKB1 ELISA Kits), c-Myc (show MYC ELISA Kits), p27(Kip1 (show CDKN1B ELISA Kits)) and cyclin (show PCNA ELISA Kits)
Strength of B-cell antigen receptor signals is strictly tuned by the interaction of CD100 (show SEMA4D ELISA Kits) with CD72; this interaction is essential for maintaining immunological homeostasis as well as generating a proper immune response.
CD72 plays a dominant role as a negative regulator of BCR (show BCR ELISA Kits) signaling in primary mature B lymphocytes.
CD72 is required to maintain B cell anergy and functions as a regulator of peripheral B cell tolerance
CD72 is an inhibitory receptor on NK cells regulating cytokine production.
Increased soluble CD72 in systemic lupus erythematosus is in association with disease activity and lupus nephritis
CD72 expression on activated B cells of SLE patients was significantly lower than that of normal controls. sema3A (show SEMA3A ELISA Kits) enhanced CD72 expression of B cells, but it was still lower in SLE patients than in normal individuals.
data demonstrated aberrant expression of CD72 exists on B cells of myasthenia gravis and multiple sclerosis patients and expression level of CD72 molecule has a significantly negative correlation with anti-AchR antibody levels in myasthenia gravis
CD72 mRNA expression level correlates with Sema4D (show SEMA4D ELISA Kits) expression in peripheral blood mononuclear cells in immune thrombocytopenia.
CD100 (show SEMA4D ELISA Kits), CD72 and CD45 (show PTPRC ELISA Kits) were expressed in placenta and exhibited different mRNA and protein levels in normal pregnancy and miscarriage. Protein levels were highly dysregulated around 10 weeks of gestation in first and second miscarriage placentas.
CD100 (show SEMA4D ELISA Kits)-CD72 interaction can be the mechanism by which NK cell communicate with B cells.
Data show that ligation of CD72 with the BU40, or with rCD100 negatively regulates KIT-mediated mast cell proliferation, chemotaxis, and chemokine (show CCL1 ELISA Kits) production.
results indicated that the presence of CD72-*2 allele decreases risk for human systemic lupus erythematosus conferred by FCGR2B (show FCGR2B ELISA Kits)-232Thr, possibly by increasing the AS isoform of CD72
CD72 is a key molecule in regulating mature B cell differentiation; CD72 signaling reduces the expression of X-box binding protein 1 (show XBP1 ELISA Kits) in B cells
increased nucleotide mutation of CD72 mRNA accounts for the decreased expression level of CD72 in B cells, and it might be related to hyperactivity of B cells in patients with SLE
Plays a role in B-cell proliferation and differentiation.
B-cell differentiation antigen CD72
, lymphocyte antigen 32
, CD72 antigen