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The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Additionally we are shipping CD79b Molecule, Immunoglobulin-Associated beta Antibodies (363) and CD79b Molecule, Immunoglobulin-Associated beta Proteins (18) and many more products for this protein.
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B-cell inhibition by cross-linking CD79b (show PDPK1 ELISA Kits) is superior to B (show TDO2 ELISA Kits)-cell depletion with anti-CD20 (show MS4A1 ELISA Kits) antibodies in treating murine collagen-induced arthritis.
Data indicate that in the absence of DGKzeta (show DGKZ ELISA Kits), the threshold for B cell antigen receptor (BCR (show BCR ELISA Kits)) signaling, measured as activation of the Ras-extracellular signal-regulated kinase (ERK (show EPHB2 ELISA Kits)) pathway, was markedly reduced in mature follicular B cells.
The cytoplasmic tail of IgG1 is strictly required for the surface expression of IgG1 when the expression of Iga/Igb heterodimer is down-regulated in B lymphoma.
endocytosed BCR (show BCR ELISA Kits) sequentially regulates MAPK (show MAPK1 ELISA Kits) and Akt (show AKT1 ELISA Kits) signaling pathways from intracellular compartments
Spontaneous mutation in the Cd79b (show PDPK1 ELISA Kits) gene leads to a block in B-lymphocyte (show AKAP17A ELISA Kits) development at the C' (early pre-B) stage
The VHDJH recombination process at the IgH locus and the survival of pro-B cells that carry these rearrangements do not depend on the expression of Ig-beta molecules.
Deletion in developing B cells leads to cell death; Igbeta expression is essential to maintain preB (show PREB ELISA Kits) cell and immature B cell survival and to mediate B cell differentiation
MHC II structural requirements for mediation of cell death signaling in a murine B cell lymphoma with Igalpha/beta
hotspot mutations of CD79B Y196 and MYD88 (show MYD88 ELISA Kits) L265 may serve as a genetic hallmark for primary central nervous system lymphoma
CD79B overexpression leading to activation of AKT (show AKT1 ELISA Kits)/MAPK (show MAPK1 ELISA Kits) is a potential mechanism underlying primary ibrutinib resistance in ABC (show ABCB6 ELISA Kits)-DLBCL, and support its utility as an effective biomarker to predict therapeutic response to ibrutinib.
Novel CD79B variations in mature B-cell non-Hodgkin's lymphoma patients were detected.
MYD88 (show MYD88 ELISA Kits) L265P and CD79B mutations were frequently detected in primary breast diffuse large B-cell lymphoma.
Oncogenic CD79B mutation is associated with primary diffuse large B-cell lymphomas of central nervous system.
Diffuse large B cell lymphomas relapsing in the CNS lack oncogenic MYD88 (show MYD88 ELISA Kits) and CD79B mutations.
Abberant expression of CD79b in non-B cells caused unwanted reactivity, rendering CD79b unsuitable for T-cell receptor - based immunotherapies.
Phosphorylation of CD79a (show CD79A ELISA Kits) causes a decrease in helical propensity in the C-terminal region, for CD79b, the opposite was observed and phosphorylation resulted in an increase of helical propensity in the C-terminal part.
results suggest that MYD88 (show MYD88 ELISA Kits) mutations, and to a lesser extent CD79B mutations, are important drivers of lymphomagenesis in PTL (show PNLIP ELISA Kits)
CD79B and MYD88 (show MYD88 ELISA Kits) mutations are associated with an older age at onset in diffuse large b-cell lymphoma with a significant overlap, which did not affect the outcome of the disease.
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.
B-cell antigen receptor complex-associated protein beta chain
, B-cell-specific glycoprotein B29
, immunoglobulin-associated B29 protein
, immunoglobulin-associated beta
, CD79b antigen (immunoglobulin-associated beta)
, CD79B antigen