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CDC42 Binding Protein Kinase alpha (DMPK-Like) Proteins (CDC42BPA)

The protein encoded by CDC42BPA is a member of the Serine/Threonine protein kinase family. Additionally we are shipping CDC42BPA Antibodies (52) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse CDC42BPA CDC42BPA 226751  
Rat CDC42BPA CDC42BPA 114116 O54874
CDC42BPA 8476 Q5VT25
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Top CDC42BPA Proteins at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$322.08
Details

CDC42BPA Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

More Proteins for CDC42 Binding Protein Kinase alpha (DMPK-Like) (CDC42BPA) Interaction Partners

Human CDC42 Binding Protein Kinase alpha (DMPK-Like) (CDC42BPA) interaction partners

  1. Data show that the fusion gene cyclin D1 (show CCND1 Proteins)/myotonic dystrophy kinase-related CDC42-binding protein kinase alpha (CCND1 (show CCND1 Proteins)/MRCK) mRNA is resistant to CCND1 (show CCND1 Proteins)-targeted miRNA regulation.

  2. the functional relevance of the LRAP25-MRCK complex in LIMK1 (show LIMK1 Proteins)-cofilin (show CFL1 Proteins) signaling and the importance of LRAP (show ERAP2 Proteins) adaptors as key determinants of MRCK cellular localization and downstream specificities.

  3. MRCK participates in mediating the effects of HMI-1a3 on HeLa cell morphology.

  4. A functional pathway involving PDK1-mediated activation of MRCKA, links EGF signaling to myosin contraction and directional migration.

  5. Data show that chelerythrine blocks cellular activity of MRCK resulted in the specific loss of NM II-associated MLC phosphorylation in the lamella, and the consequential suppression of cell migration.

  6. MRCKalpha takes part in transferrin (show Tf Proteins) (Tf)-iron uptake, probably via regulation of Tf- TfR (show TFRC Proteins) endocytosis/endosome trafficking that is dependent on the cellular cytoskeleton.

  7. Class II histone deacetylases are directly recruited by BCL6 (show BCL6 Proteins) transcriptional repressor

  8. a Cdc42 (show CDC42 Proteins)-MRCK signal mediates myosin-dependent cell motility and there is convergence between Rho and Cdc42 (show CDC42 Proteins) signalling

  9. The level of MRCKalpha mRNA in various tissues strongly positively correlates with the level of TfR (show TFRC Proteins) mRNA, indicating its possible role in the transferrin (show Tf Proteins) iron uptake pathway.

  10. findings report that the Notch1 (show NOTCH1 Proteins) gene is a p53 (show TP53 Proteins) target in human keratinocytes with a role in tumor suppression of this cell type through negative regulation of the ROCK1 (show ROCK1 Proteins)/2 and MRCKalpha kinases

CDC42BPA Protein Profile

Protein Summary

The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported.

Gene names and symbols associated with CDC42BPA

  • CDC42 binding protein kinase alpha (DMPK-like) (CDC42BPA)
  • CDC42-binding protein kinase alpha (CDC42BPA)
  • CDC42 binding protein kinase alpha (DMPK-like) (cdc42bpa)
  • CDC42 binding protein kinase alpha (Cdc42bpa)
  • A930014J19Rik protein
  • CDC42BPA protein
  • DMPK-like protein
  • MRCK protein
  • MRCKA protein
  • PK428 protein

Protein level used designations for CDC42BPA

serine/threonine-protein kinase MRCK alpha , CDC42 binding protein kinase alpha (DMPK-like) , CDC42 binding protein kinase alpha-like , serine/threonine-protein kinase MRCK alpha-like , CDC42-binding protein kinase alpha , myotonic dystrophy kinase-related CDC-42-binding kinase-alpha , MRCK alpha , Ser-Thr protein kinase related to the myotonic dystrophy protein kinase , myotonic dystrophy kinase-related CDC42-binding kinase alpha , myotonic dystrophy protein kinase-like alpha , mytonic dystrophy kinase-related Cdc42-binding kinase , CDC42 binidng protein kinase beta , CDC42-binding protein kinase alpha (DMPK-like) , DMPK-like alpha , myotonic dystrophy kinase-related CDC42-binding protein kinase alpha , ser-thr protein kinase PK428 , ser-thr protein kinase related to the myotonic dystrophy protein kinase

GENE ID SPECIES
416746 Gallus gallus
480107 Canis lupus familiaris
538392 Bos taurus
697811 Macaca mulatta
738981 Pan troglodytes
100019700 Monodelphis domestica
100054548 Equus caballus
100082535 Ornithorhynchus anatinus
100157850 Sus scrofa
100182779 Ciona intestinalis
100228637 Taeniopygia guttata
100377053 Saccoglossus kowalevskii
100412330 Callithrix jacchus
100457631 Pongo abelii
100465611 Ailuropoda melanoleuca
787410 Bos taurus
100545977 Meleagris gallopavo
100604711 Nomascus leucogenys
226751 Mus musculus
114116 Rattus norvegicus
8476 Homo sapiens
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