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CRTC3 is a member of the CREB regulated transcription coactivator gene family. Additionally we are shipping CRTC3 Antibodies (32) and CRTC3 Kits (4) and many more products for this protein.
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beta-agonists or catecholamines released during intense exercise induce Creb (show CREB1 Proteins)-mediated transcriptional programs through activation of its obligate coactivators Crtc2 (show CRTC2 Proteins) and Crtc3.
CRTC3 plays a selective role in mitochondrial biogenesis in response to rotenone
the cAMP response element binding (CREB) coactivator Crtc3 promotes obesity by attenuating beta-adrenergic receptor signalling in adipose tissue
revealing neither correlation between the cellular composition and CRTC1-MAML2 fusions nor presence of CRTC3-MAML2 fusions in cutaneous hidradenoma
The CRTC3 polymorphism rs3862434 is associated with the plasma level of total cholesterol, and rs11635252 is associated with the risks of overweight and hypertriglyceridemia in a Chinese Han population.
Metaplastic Warthin tumor and metaplastic pleomorphic adenoma of salivary glands did not harbor CRTC1-MAML2 and CRTC3-MAML2 fusion transcripts, respectively, or MAML2 gene rearrangement.
mucoepidermoid carcinoma of the salivary glands positive for CRTC1-MAML2 or CRTC3-MAML2 fusion formed a favourable tumour subset that was distinct from fusion-negative cases
As a common human CRTC3 variant with increased transcriptional activity is associated with adiposity in two distinct Mexican-American cohorts, results suggest that adipocyte CRTC3 may play a role in the development of obesity in humans
Mucoepidermoid carcinomas possessing CRTC3-MAML2 fusion may be associated with favorable clinicopathological features and patients may be younger than those with CRTC1-MAML2 fusion or those with no detectable gene fusion.
transducer of regulated cyclic AMP-response element-binding protein 3 (show HSPB3 Proteins) (TORC3), a co-activator of CREB (show CREB1 Proteins), is involved in Tax (show CNTN2 Proteins)-induced transcriptional activation from the HTLV-I LTR
These results strongly suggest that TORCs play a key role in linking these external signals to the transcriptional program of adaptive mitochondrial biogenesis by activating PGC-1alpha gene transcription.
BCL3 (show BCL3 Proteins) functions as a repressor of HTLV-1 LTR-mediated transcription through interactions with TORC3
This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
transducer of regulated CREB protein 3
, CREB regulated transcription coactivator 3
, CREB-regulated transcription coactivator 3
, transducer of CREB protein 3
, transducer of regulated cAMP response element-binding protein 3
, CREB-regulated transcription coactivator 3-like
, transducer of regulated cAMP response element-binding protein (CREB) 3