anti-C-Type Lectin Domain Family 4, Member D (CLEC4D) Antibodies

CLEC4D encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Additionally we are shipping CLEC4D Proteins (10) and CLEC4D Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CLEC4D 338339 Q8WXI8
CLEC4D 17474 Q9Z2H6
CLEC4D 362432 Q69FH1
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Top anti-CLEC4D Antibodies at antibodies-online.com

Showing 10 out of 66 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Allophycocyanin FACS Detection of CLEC4D/CLECSF8 in Whole Blood Monocytes by Flow Cytometry. Whole blood monocytes were stained with Mouse Anti-Human CLEC4D/CLECSF8 APC-conjugated Monoclonal Antibody. Detection of CLEC4D/CLECSF8 in Whole Blood Monocytes by Flow Cytometry. Whole blood monocytes were stained with Mouse Anti-Human CLEC4D/CLECSF8 APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$367.50
Details
Human Mouse Un-conjugated FACS, WB Detection of CLEC4D/CLECSF8 in Human Monocytes by Flow Cytometry. Human whole blood monocytes were stained with Mouse Anti-Human CLEC4D/CLECSF8 Monoclonal Antibody. Detection of CLEC4D/CLECSF8 in Human Monocytes by Flow Cytometry. Human whole blood monocytes were stained with Mouse Anti-Human CLEC4D/CLECSF8 Monoclonal Antibody. 100 μg Log in to see 8 to 9 Days
$262.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse PE FACS Detection of CLEC4D/CLECSF8 in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human CLEC4D/CLECSF8 PE-conjugated Monoclonal Antibody. Detection of CLEC4D/CLECSF8 in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human CLEC4D/CLECSF8 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$320.25
Details
Human Rabbit Un-conjugated ELISA   100 μg Log in to see 20 to 21 Days
$273.90
Details
Human Rabbit Un-conjugated WB CLEC4D Antibody (Center)  western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the CLEC4D antibody detected the CLEC4D protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 16 Days
$323.13
Details
Human Goat Un-conjugated FACS, WB Detection of CLEC4D/CLECSF8 in Human Monocytes by Flow Cytometry. Human whole blood monocytes were stained with Goat Anti-Human CLEC4D/CLECSF8 Antigen Affinity-purified Polyclonal Antibody. Detection of CLEC4D/CLECSF8 in Human Monocytes by Flow Cytometry. Human whole blood monocytes were stained with Goat Anti-Human CLEC4D/CLECSF8 Antigen Affinity-purified Polyclonal Antibody. 100 μg Log in to see 8 to 9 Days
$372.75
Details
Human Mouse Alexa Fluor 488 FACS   0.1 mg Log in to see 10 to 13 Days
$447.56
Details
Human Mouse Alexa Fluor 350 FACS   0.1 mg Log in to see 10 to 13 Days
$447.56
Details

CLEC4D Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Mouse (Murine)


Rat (Rattus)


Top referenced anti-CLEC4D Antibodies

  1. Human Monoclonal CLEC4D Primary Antibody for FACS - ABIN4897646 : Graham, Gupta, Schafer, Reid, Kimberg, Dennehy, Hornsell, Guler, Campanero-Rhodes, Palma, Feizi, Kim, Sobieszczuk, Willment, Brown: The C-type lectin receptor CLECSF8 (CLEC4D) is expressed by myeloid cells and triggers cellular activation through Syk kinase. in The Journal of biological chemistry 2012 (PubMed)

  2. Human Monoclonal CLEC4D Primary Antibody for ELISA - ABIN1998795 : Arce, Martínez-Muñoz, Roda-Navarro, Fernández-Ruiz: The human C-type lectin CLECSF8 is a novel monocyte/macrophage endocytic receptor. in European journal of immunology 2004 (PubMed)

More Antibodies against CLEC4D Interaction Partners

Human C-Type Lectin Domain Family 4, Member D (CLEC4D) interaction partners

  1. Results show the molecular mechanism of glycolipid recognition through C-type lectin (show MBL2 Antibodies) receptors, which may provide clues to rational design for effective adjuvants.

  2. CLECSF8 functions as an activation receptor on myeloid cells and associates with a novel adaptor molecule

  3. Cross-linking of the receptor leads to a rapid internalization suggesting that CLECSF8 constitutes and endocytic receptor.

Mouse (Murine) C-Type Lectin Domain Family 4, Member D (CLEC4D) interaction partners

  1. activation of CLRs Dectin-2 (show CLEC6A Antibodies) and Dectin-3 by fungi infections triggers them for ubiquitination and degradation in a Syk (show SYK Antibodies)-dependent manner.

  2. The authors report that microbial stimulation triggers Mincle (Clec4e (show CLEC4E Antibodies)) expression through the myeloid differentiation primary response gene 88 (MyD88 (show MYD88 Antibodies)) pathway; a process that does not require MCL (Clecsf8, Clec4d). Conversely, they show that MCL is constitutively expressed but retained intracellularly until Mincle (show CLEC4E Antibodies) is induced, whereupon the receptors form heterodimers which are translocated to the cell surface.

  3. Data show that Mincle (show CLEC4E Antibodies), the inducible receptor for mycobacterial cord factor, is the key switch for the transition of macrophages from cytokine expression to high nitric oxide production.

  4. MCL regulates the development of vaccine-induced Th17 cells and protective immunity against lethal experimental infection with Blastomyces dermatitidis.

  5. major contributor to activation of innate immunity against M. bovis in experimental model, mirrors Mincle (show CLEC4E Antibodies) expression

  6. Clecsf8-/- mice exhibit higher bacterial burdens and increased mortality upon Mycobacterium tuberculosis infection.

  7. These results suggest that MCL positively regulates Mincle (show CLEC4E Antibodies) expression through protein-protein interaction via its stalk region, thereby magnifying Mincle (show CLEC4E Antibodies)-mediated signaling.

  8. Trehalose 6,6'-dimycolate-induced Mincle (show CLEC4E Antibodies) expression is dependent on Dectin-3-mediated NF-kappaB (show NFKB1 Antibodies) activation through the CARD9 (show CARD9 Antibodies)-BCL10 (show BCL10 Antibodies)-MALT1 (show MALT1 Antibodies) complex.

  9. Compared to their respective homodimers, Dectin-3 and Dectin-2 (show CLEC6A Antibodies) heterodimers bound alpha-mannans more effectively, leading to potent inflammatory responses against fungal infections.

  10. Clec4d(-/-) neutrophils did not exhibit any defect in bacterial clearance

CLEC4D Antigen Profile

Protein Summary

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Gene names and symbols associated with CLEC4D

  • C-type lectin domain family 4, member D (CLEC4D) antibody
  • C-type lectin domain family 4, member d (Clec4d) antibody
  • C-type lectin domain family 4, member D (Clec4d) antibody
  • CLEC-6 antibody
  • CLEC4D antibody
  • CLEC6 antibody
  • Clecsf8 antibody
  • Mcl antibody
  • Mpcl antibody

Protein level used designations for CLEC4D

C-type lectin domain family 4, member D , C-type lectin domain family 4 member D , C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 8 , C-type lectin receptor , C-type lectin superfamily member 8 , C-type lectin-like receptor 6 , macrophage C-type lectin , C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 8 , C-type lectin, superfamily member 8 , macrophage-restricted C-type lectin

GENE ID SPECIES
473405 Pan troglodytes
611536 Canis lupus familiaris
616646 Bos taurus
338339 Homo sapiens
17474 Mus musculus
362432 Rattus norvegicus
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