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Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.. Additionally we are shipping CAPN1 Antibodies (121) and CAPN1 Proteins (8) and many more products for this protein.
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Attenuation of atherosclerotic lesions/inflammation in ApoE (show APOE ELISA Kits) KO mice by simvastatin might be associated with the downregulation of CD36 (show CD36 ELISA Kits) and calpain-1.
Leukocyte calpain-1/calpain-2 (show CAPN2 ELISA Kits) deficiency reduces angiotensin II-induced inflammation and atherosclerosis but not abdominal Aortic aneurysms in mice.
TnT3 regulates transcription of Cacna1s (show CACNA1S ELISA Kits), the gene encoding Cav1.1 (show CACNA1S ELISA Kits). Knocking down TnT3 in vivo downregulated Cav1.1 (show CACNA1S ELISA Kits).
Taken together, our findings suggested that DHRS7C maintains intracellular Ca(2+) homeostasis involving the ER/SR and that functional loss of DHRS7C leads to Ca(2+) overload in the cytosol and ER/SR, resulting in enlarged cellular morphology via calpain activation
In conclusion, calpain was involved in oxygen glucose deprivation-induced RGC-5 necroptosis with the increased expression of its downstream molecule tAIF.
CRYbetaA3/A1-crystallin has a role in preventing nuclear cataract impaired lysosomal cargo clearance and calpain activation
Capn1 (show CAPNL1 ELISA Kits) protein and activity in mitochondria were elevated in diabetic mouse hearts. Increased mitochondrial Capn1 (show CAPNL1 ELISA Kits) was associated with increased mitochondrial ROS (show ROS1 ELISA Kits) generation and oxidative damage and reduced ATP5A1 (show ATP5A1 ELISA Kits) protein and ATP synthase activity.
LOX-1 (show OLR1 ELISA Kits) is, at least in part, responsible for the inhibitory effect of ox-LDL on macrophage migration and this process involves calpain-1 and -2.
Over-expression of Cast inhibits calpain activation and attenuates post-infarction myocardial remodeling.
Junctophilin-2 (show JPH2 ELISA Kits) is cleaved by calpain at multiple sites, resulting in dysfunctional junctophilin-2 (show JPH2 ELISA Kits) truncations.
Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
calpain 1, large subunit
, CANP 1
, calcium-activated neutral proteinase 1
, calpain mu-type
, calpain-1 catalytic subunit
, calpain-1 large subunit
, calpain 1