Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) Proteins (CEACAM1)

CEACAM1 encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Additionally we are shipping Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) Antibodies (300) and Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) Kits (27) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CEACAM1 26365 P31809
CEACAM1 634 P13688
CEACAM1 81613 P16573
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Top Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) Proteins at antibodies-online.com

Showing 10 out of 32 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 100 μg Log in to see 20 to 21 Days
$382.80
Details
HOST_Human Cells Human Fc Tag,His tag 100 μg Log in to see 20 to 21 Days
$382.80
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,244.78
Details
HOST_HEK-293 Cells Human His tag Human CEACAM-1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 92%. 100 μg Log in to see 2 to 3 Days
$275.00
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Mammalian Cells Human His tag   50 μg Log in to see 4 Days
$280.50
Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 20 to 21 Days
$382.80
Details
HOST_HEK-293 Cells Human His tag Validation with Western Blot 10 μg Log in to see 12 to 15 Days
$345.35
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HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_Human Cells Rat His tag 100 μg Log in to see 20 to 21 Days
$382.80
Details

CEACAM1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , , ,
, ,
Human , , , , , , , ,
, , , ,
Rat (Rattus) , ,

More Proteins for Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) (CEACAM1) Interaction Partners

Cow (Bovine) Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) (CEACAM1) interaction partners

  1. our data show that human and bovine CEACAM1 can both inhibit NK-cell cytotoxicity although they differ in their intracellular signaling motifs

  2. Data from cultured aortic endothelial cells suggest that CEACAM1 is involved in regulation of vascular endothelial cell reactions to oxidative stress/lipid peroxidation and in regulation of nitric oxide production in large vessels such as aorta.

  3. This data represents the first report of a functional link between CEACAM1 and the VEGFR2 (show KDR Proteins)/Akt (show AKT1 Proteins)/eNOS (show NOS3 Proteins)-mediated vascular permeability pathway.

  4. CEACAM1 has two alleles and serves as a pathogen receptor in cattle.

Mouse (Murine) Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) (CEACAM1) interaction partners

  1. A 30-day high fat feeding regimen demonstrated that white adipose tissue-derived fatty acids repressed hepatic CEACAM1-dependent regulation of insulin (show INS Proteins) and lipid metabolism in 3-month-old male C57BL/6J mice.

  2. REVIEW: summarizes the vascular effects of CEACAM1 and focuses on its role in vascular morphogenesis and endothelial barrier regulation

  3. CEACAM1 exacerbates hypoxic cardiomyocyte injury and post-infarction cardiac remodeling by enhancing cardiomyocyte mitochondrial dysfunction and endoplasmic reticulum stress-induced apoptosis.

  4. The increase in total fat mass in Cc1(-/-) mice is mainly attributed to hyperphagia and reduced spontaneous physical activity. Although the contribution of the loss of CEACAM1 from anorexigenic proopiomelanocortin (show POMC Proteins) neurons in the arcuate nucleus is unclear, leptin (show LEP Proteins) resistance and elevated hypothalamic fatty-acid synthase (show FASN Proteins) activity could underlie altered energy balance in these mice.

  5. Ceacam1 is essential for normal integrin aIIbb3-mediated platelet function; the disruption of mouse Ceacam1 induced moderate integrin aIIbb3-mediated functional defects.

  6. hepatic CEACAM1 expression at fasting is mediated by Pparalpha (show PPARA Proteins)-dependent mechanisms.

  7. Gram-positive bacteria promote the mRNA expression of CEACAM1 or CEACAM20 in the small intestine. Inflammatory cytokines or butyrate likely participates in such effects of commensal bacteria.

  8. CEACAM1 is a crucial regulator of B-cell survival, influencing B-cell numbers and protective antiviral antibody responses

  9. High-fat diet amplifies the permissive effect of Ceacam1 deletion on renal expression of all renin (show REN Proteins)-angiotensin system components, PI3K phosphorylation, inflammation, and fibrosis.

  10. Ceacam1L acts as a crucial factor in glioblastoma-initiating cell maintenance and tumorigenesis by activating c-Src (show SRC Proteins)/STAT3 (show STAT3 Proteins) signaling. Monomers of the cytoplasmic domain of Ceacam1L bound to c-Src (show SRC Proteins) and STAT3 (show STAT3 Proteins) and induced their phosphorylation.

Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) (CEACAM1) interaction partners

  1. Results report that CEACAM1 was uniquely expressed at high levels in both human neoplastic mast cells (mastocytosis) and medullary thyroid carcinoma cell (MTC (show MT1A Proteins)) lines, and suggest that the dominantly interacting proteins SHP1 (show PTPN6 Proteins) or SFK determine whether CEACAM1-L displays a positive or negative role in tumor cells. .

  2. SASH1 (show SASH1 Proteins) acts through NOTCH1 (show NOTCH1 Proteins) and its inhibitor DLK1 (show DLK1 Proteins) in a three-dimensional model of lumenogenesis involving CEACAM1.

  3. CEACAM1 also inhibits viral spread in ex vivo human decidua organ culture.

  4. In enterocytic C2BBe1 cells, Candida albicans caused a transient tyrosine phosphorylation of CEACAM1 and induced higher expression of membrane-bound CEACAM1 and soluble CEACAM6.

  5. REVIEW: summarizes the vascular effects of CEACAM1 and focuses on its role in vascular morphogenesis and endothelial barrier regulation

  6. We also found that MMP12 (show MMP12 Proteins) facilitated type I collagen induced platelet aggregation, adhesion and alpha granule secretion. Similarly, one short peptide, WYKG, facilitated type I collagen induced platelet alpha granule secretion. We conclude that platelet express MMP12 (show MMP12 Proteins) may facilitate platelet activation through shedding of CEACAM1.

  7. We demonstrate that recombinant Neisseria Opa proteins reconstituted into liposomes retain the ability to recognize and interact with CEACAM1 and 3 in vitro but do not maintain receptor specificity compared to that of Opa proteins natively expressed by Neisseria gonorrhoeae.

  8. use NMR cross-correlation measurements to examine the effect of glycosylation on CEACAM1-IgV dimerization and use residual dipolar coupling (RDC) measurements to characterize the solution structure of the non-glycosylated form.

  9. miRNA-342 Regulates CEACAM1-induced Lumen Formation in a Three-dimensional Model of Mammary Gland Morphogenesis.

  10. The diffuse and cytoplasmic expression of CD66a may involve the early stage of the hepatocellular carcinoma , and the loss of CD66a expression indicates tumor progression.

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) (CEACAM1) Protein Profile

Protein Summary

This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.

Gene names and symbols associated with CEACAM1

  • carcinoembryonic antigen-related cell adhesion molecule 1 (ceacam1)
  • carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8)
  • carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1)
  • carcinoembryonic antigen-related cell adhesion molecule 1 (Ceacam1)
  • carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) (CEACAM1)
  • carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) (Ceacam1)
  • carcinoembryonic antigen-related cell adhesion molecule 18 (Ceacam18)
  • 2010110O04Rik protein
  • bb-1 protein
  • BGP protein
  • BGP1 protein
  • BGPI protein
  • BGPR protein
  • C-CAM protein
  • Cc1 protein
  • Ccam1 protein
  • CD66a protein
  • Cea-1 protein
  • Cea-7 protein
  • Cea1 protein
  • Cea7 protein
  • CEACAM1 protein
  • CEACAM8 protein
  • hm:zeh0068 protein
  • Hv-2 protein
  • Hv2 protein
  • mCEA1 protein
  • MGC142545 protein
  • Mhv-1 protein
  • MHVR protein
  • MHVR1 protein
  • mmCGM1 protein
  • mmCGM1a protein
  • mmCGM2 protein
  • zeh0068 protein

Protein level used designations for CEACAM1

carcinoembryonic antigen-related cell adhesion molecule 1 , carcinoembryonic antigen-related cell adhesion molecule 8 , CEACAM1b-3L , CEACAM1b-3S , CEACAM1b-3Ls , CEACAM1b-3Ss , BGP-1 , CEA-related cell adhesion molecule 1 , MHV-R , biliary glycoprotein 1 , biliary glycoprotein D , carcinoembryonic antigen 1 , carcinoembryonic antigen 7 , hepatitis virus (MHV-4) susceptibility , hepatitis virus receptor , murine hepatitis virus receptor , CD66a antigen , antigen CD66 , ATP-dependent taurocolate-carrier protein , C-CAM 105 , CEA-related cell adhesion molecule 1 (bone gamma-carboxyglutamic acid (Gla) protein) (osteocalcin) , GP110 , bone gamma-carboxyglutamic acid (Gla) protein , cell-CAM 105 , ecto-ATPase , osteocalcin , pp120 , pp120/ecto-ATPase

GENE ID SPECIES
114465 Danio rerio
404118 Bos taurus
612435 Canis lupus familiaris
26365 Mus musculus
634 Homo sapiens
81613 Rattus norvegicus
72431 Mus musculus
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