CEACAM1 Protein (AA 35-428) (His tag)

Catalog No. ABIN1096365

Product Details

Target: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Protein Type: Recombinant

Protein Characteristics: AA 35-428

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This CEACAM1 protein is labelled with His tag.

Purpose: Recombinant Human CEACAM1/CD66a (C-6His)

Sequence: QLTTESMPFN VAEGKEVLLL VHNLPQQLFG YSWYKGERVD GNRQIVGYAI GTQQATPGPA NSGRETIYPN ASLLIQNVTQ NDTGFYTLQV IKSDLVNEEA TGQFHVYPEL PKPSISSNNS NPVEDKDAVA FTCEPETQDT TYLWWINNQS LPVSPRLQLS NGNRTLTLLS VTRNDTGPYE CEIQNPVSAN RSDPVTLNVT YGPDTPTISP SDTYYRPGAN LSLSCYAASN PPAQYSWLIN GTFQQSTQEL FIPNITVNNS GSYTCHANNS VTGCNRTTVK TIIVTELSPV VAKPQIKASK TTVTGDKDSV NLTCSTNDTG ISIRWFFKNQ SLPSSERMKL SQGNTTLSIN PVKREDAGTY WCEVFNPISK NQSDPIMLNV NYNALPQENG LSPGVDHHHH HH

Characteristics: Recombinant Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/CEACAM1 produced by transfected human cells is a secreted protein with sequence (Q35-G428) of Human CEACAM1 fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Alternative Name: ceacam-1 (CEACAM1 Products)

Synonyms: BGP Protein, BGP1 Protein, BGPI Protein, CD66e Protein, CEA Protein, zeh0068 Protein, hm:zeh0068 Protein, CEACAM8 Protein, CEACAM1 Protein, MGC142545 Protein, BGPR Protein, Bgp Protein, CD66a Protein, Ccam1 Protein, Bgp1 Protein, C-CAM Protein, Cc1 Protein, Cea-1 Protein, Cea-7 Protein, Cea1 Protein, Cea7 Protein, Hv-2 Protein, Hv2 Protein, MHVR Protein, MHVR1 Protein, Mhv-1 Protein, bb-1 Protein, mCEA1 Protein, mmCGM1 Protein, mmCGM1a Protein, mmCGM2 Protein, carcinoembryonic antigen related cell adhesion molecule 1 Protein, carcinoembryonic antigen related cell adhesion molecule 5 Protein, carcinoembryonic antigen-related cell adhesion molecule 1 Protein, carcinoembryonic antigen-related cell adhesion molecule 6 Protein, CEACAM1 Protein, CEACAM5 Protein, ceacam1 Protein, Ceacam1 Protein, LOC101103343 Protein

Sub Type: Fusionprotein

Background: Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) is a member of the Carcinoembryonic Antigen (CEA) family, which belongs to the immunoglobulin superfamily. CEACAM1 is originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it is found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. CEACAM1 mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. In addition, CEACAM1 plays a important role in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses.
Alternative Names: Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1, Biliary Glycoprotein 1, BGP-1, CD66a, CEACAM1, BGP, BGP1

Molecular Weight: 44.33 kDa

UniProt: P13688