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Carnosine Dipeptidase 1 (Metallopeptidase M20 Family) Proteins (CNDP1)

CNDP1 encodes a member of the M20 metalloprotease family. Additionally we are shipping Carnosine Dipeptidase 1 (Metallopeptidase M20 Family) Antibodies (89) and Carnosine Dipeptidase 1 (Metallopeptidase M20 Family) Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CNDP1 84735 Q96KN2
CNDP1 338403 Q8BUG2
Rat CNDP1 CNDP1 307212 Q66HG3
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Top Carnosine Dipeptidase 1 (Metallopeptidase M20 Family) Proteins at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 10 μg Log in to see 16 Days
$206.80
Details
HOST_HEK-293 Cells Human His tag Human CNDP1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 50 μg Log in to see 2 to 3 Days
$319.00
Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Mammalian Cells Human His tag   50 μg Log in to see 5 Days
$522.50
Details
HOST_Human Human His tag   10 μg Log in to see 11 Days
$300.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_HEK-293 Human His tag   0.05 mg Log in to see 2 to 3 Days
$584.38
Details
HOST_HEK-293 Cells Human Un-conjugated   10 μg Log in to see 2 to 3 Days
$178.50
Details

CNDP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , ,
, ,
Mouse (Murine) ,

Top referenced Carnosine Dipeptidase 1 (Metallopeptidase M20 Family) Proteins

  1. Human CNDP1 Protein expressed in HEK-293 Cells - ABIN2180890 : Lenney, George, Weiss, Kucera, Chan, Rinzler: Human serum carnosinase: characterization, distinction from cellular carnosinase, and activation by cadmium. in Clinica chimica acta; international journal of clinical chemistry 1982 (PubMed)
    Show all 4 references for ABIN2180890

  2. Human CNDP1 Protein expressed in Human Cells - ABIN2002023 : Riedl, Koeppel, Brinkkoetter, Sternik, Steinbeisser, Sauerhoefer, Janssen, van der Woude, Yard: A CTG polymorphism in the CNDP1 gene determines the secretion of serum carnosinase in Cos-7 transfected cells. in Diabetes 2007 (PubMed)
    Show all 3 references for ABIN2002023

  3. Mouse (Murine) CNDP1 Protein expressed in Human Cells - ABIN2008450 : Sauerhöfer, Yuan, Braun, Deinzer, Neumaier, Gretz, Floege, Kriz, van der Woude, Moeller: L-carnosine, a substrate of carnosinase-1, influences glucose metabolism. in Diabetes 2007 (PubMed)
    Show all 3 references for ABIN2008450

More Proteins for Carnosine Dipeptidase 1 (Metallopeptidase M20 Family) (CNDP1) Interaction Partners

Human Carnosine Dipeptidase 1 (Metallopeptidase M20 Family) (CNDP1) interaction partners

  1. The experimentally measured higher affinity of homocarnosine for the enzyme relative to l-carnosine might be explained, at least in part, by more extensive interactions inside the monomeric and dimeric hCN1 (show HCN1 Proteins)'s active site.

  2. CNDP1 and CARNS are expressed in glomeruli and tubular cells; TauT (show TAUT Proteins) is expressed in renal epithelial cells; CDNP1 may have a role in diabetic neuropathy

  3. Data shows that higher carnosine content in human skeletal muscle is positively associated with insulin (show INS Proteins) resistance and fasting metabolic preference for glucose.

  4. In gastrointestinal cancer, reduced plasma levels of CNDP1 associate with signs of catabolism and poor outcome.

  5. Alterations of serum carnosinase (CN1) activity has been associated with several pathological conditions, such as neurological disorders, chronic diseases and cancer

  6. Rs12604675-A in CNDP1 may confer susceptibility to overt proteinuria in Japanese women with type 2 diabetes.

  7. In this review, correlations between serum carnosine and carnosinase activity and polymorphism in CNDP1 gene are analyzed. The role of CNDP1 gene polymorphism the development of diabetic nephropathy and non-diabetic chronic kidney disease is discussed.

  8. Plasma levels of FLT (show FLT1 Proteins) and S100A9 (show S100A9 Proteins) proteins are up-regulated and CNDP1 levels are down-regulated in patients with glioblastoma.

  9. Common variants in CNDP1 and CNDP2 (show CNDP2 Proteins) play a role in susceptibility to kidney disease in patients with type 2 diabetes.

  10. These findings provide nominal evidence supporting a role between CNDP1 variants and diabetic kidney disease.

Carnosine Dipeptidase 1 (Metallopeptidase M20 Family) (CNDP1) Protein Profile

Protein Summary

This gene encodes a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This gene contains trinucleotide (CTG) repeat length polymorphism in the coding region.

Gene names and symbols associated with CNDP1

  • carnosine dipeptidase 1 (metallopeptidase M20 family) (cndp1)
  • carnosine dipeptidase 1 (metallopeptidase M20 family) (CNDP1)
  • carnosine dipeptidase 1 (metallopeptidase M20 family) (Cndp1)
  • AI746433 protein
  • Cn1 protein
  • CNDP1 protein
  • CPGL2 protein
  • HsT2308 protein

Protein level used designations for CNDP1

carnosine dipeptidase 1 (metallopeptidase M20 family) , beta-Ala-His dipeptidase , CNDP dipeptidase 1 , carnosinase 1 , glutamate carboxypeptidase-like protein 2 , serum carnosinase

GENE ID SPECIES
398917 Xenopus laevis
421012 Gallus gallus
476165 Canis lupus familiaris
614200 Bos taurus
695195 Macaca mulatta
100061728 Equus caballus
100135225 Xenopus (Silurana) tropicalis
100172721 Pongo abelii
100554161 Anolis carolinensis
100583488 Nomascus leucogenys
84735 Homo sapiens
338403 Mus musculus
307212 Rattus norvegicus
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