CNDP1 Protein (AA 27-507) (His tag)

Catalog No. ABIN1096230

Product Details

Target: CNDP1 (Carnosine Dipeptidase 1 (Metallopeptidase M20 Family) (CNDP1))

Protein Type: Recombinant

Protein Characteristics: AA 27-507

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This CNDP1 protein is labelled with His tag.

Purpose: Recombinant Human Carnosine Dipeptidase 1/CNDP1 (C-6His)

Sequence: PSPPPALLEK VFQYIDLHQD EFVQTLKEWV AIESDSVQPV PRFRQELFRM MAVAADTLQR LGARVASVDM GPQQLPDGQS LPIPPVILAE LGSDPTKGTV CFYGHLDVQP ADRGDGWLTD PYVLTEVDGK LYGRGATDNK GPVLAWINAV SAFRALEQDL PVNIKFIIEG MEEAGSVALE ELVEKEKDRF FSGVDYIVIS DNLWISQRKP AITYGTRGNS YFMVEVKCRD QDFHSGTFGG ILHEPMADLV ALLGSLVDSS GHILVPGIYD EVVPLTEEEI NTYKAIHLDL EEYRNSSRVE KFLFDTKEEI LMHLWRYPSL SIHGIEGAFD EPGTKTVIPG RVIGKFSIRL VPHMNVSAVE KQVTRHLEDV FSKRNSSNKM VVSMTLGLHP WIANIDDTQY LAAKRAIRTV FGTEPDMIRD GSTIPIAKMF QEIVHKSVVL IPLGAVDDGE HSQNEKINRW NYIEGTKLFA AFFLEMAQLH VDHHHHHH

Characteristics: Recombinant Human Carnosine Dipeptidase 1/CNDP1 produced by transfected human cells is a secreted protein with sequence (Ser27-His507) of Human CNDP1 fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 7.5.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: -80 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: CNDP1 (Carnosine Dipeptidase 1 (Metallopeptidase M20 Family) (CNDP1))

Alternative Name: cndp1 (CNDP1 Products)

Synonyms: cn1 Protein, cpgl2 Protein, CNDP1 Protein, CN1 Protein, CPGL2 Protein, HsT2308 Protein, AI746433 Protein, Cn1 Protein, carnosine dipeptidase 1 (metallopeptidase M20 family) L homeolog Protein, carnosine dipeptidase 1 Protein, carnosine dipeptidase 1 (metallopeptidase M20 family) Protein, cndp1.L Protein, CNDP1 Protein, cndp1 Protein, Cndp1 Protein

Sub Type: Fusionprotein

Background: Carnosine Dipeptidase 1 (CNDP1) belongs to the M20 metalloprotease family. CNDP1 is specifically expressed in the brain, serum and adult nervous central system. It is identified as human carnosinase. CNDP1 contains trinucleotide (CTG) repeat length polymorphism in the coding region and is inhibited by the metal chelator 1,10-o-phenantrolin. In addition, CNDP1 can hydrolyse the beta-Ala|-His dipeptide (carnosine), anserine, Xaa-|-His dipeptides and other dipeptides including homocarnosine. CNDP1 deficiency has been associated with homocarnosinosis disease.
Alternative Names: Beta-Ala-His Dipeptidase, CNDP Dipeptidase 1, Carnosine Dipeptidase 1, Glutamate Carboxypeptidase-Like Protein 2, Serum Carnosinase, CNDP1, CN1, CPGL2

Molecular Weight: 54.9 kDa

UniProt: Q96KN2