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Caveolin 1, Caveolae Protein, 22kDa Proteins (CAV1)

The scaffolding protein encoded by CAV1 is the main component of the caveolae plasma membranes found in most cell types. Additionally we are shipping Caveolin-1 Antibodies (302) and Caveolin-1 Kits (87) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CAV1 12389 P49817
CAV1 25404  
CAV1 857 Q03135
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Top Caveolin-1 Proteins at antibodies-online.com

Showing 10 out of 38 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Dog His tag Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 1-178) protein (His tag) 500 μg Log in to see 56 to 66 Days
$1,155.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$830.50
Details
HOST_Escherichia coli (E. coli) Mouse His tag,GST tag 100 μg Log in to see 11 to 13 Days
$915.20
Details
HOST_Wheat germ Human GST tag   10 μg Log in to see 9 Days
$405.71
Details
Yeast Cat His tag   1 mg Log in to see 56 to 66 Days
$2,414.50
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,414.50
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,414.50
Details
Yeast Rhinoceros His tag   1 mg Log in to see 56 to 66 Days
$2,414.50
Details

CAV1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
,
Rat (Rattus) ,

Human , ,
, ,

Top referenced Caveolin-1 Proteins

  1. Human Caveolin-1 Protein expressed in Wheat germ - ABIN1348146 : Kastelijn, van Moorsel, Kazemier, Roothaan, Ruven, Kwakkel-van Erp, van de Graaf, Zanen, van Kessel, Grutters: A genetic polymorphism in the CAV1 gene associates with the development of bronchiolitis obliterans syndrome after lung transplantation. in Fibrogenesis & tissue repair 2011 (PubMed)
    Show all 4 references for ABIN1348146

More Proteins for Caveolin 1, Caveolae Protein, 22kDa (CAV1) Interaction Partners

Zebrafish Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

  1. Single epicardial cell transcriptome sequencing identifies Caveolin 1 as an essential factor in zebrafish heart regeneration.

  2. The development of transgenic zebrafish lines expressing CLTA (show CLTA Proteins) fused to dsRed and CAV1 fused to GFP is reported.

  3. maternally expressed zebrafish Cav-1 regulates dorsoventral patterning by limiting nuclear translocation of active beta-catenin (show CTNNB1 Proteins)

  4. These results support important and previously unanticipated roles for the Caveolin-1 isoforms in vertebrate organogenesis.

Xenopus laevis Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

  1. interactions of cav1 at lipid-exposed domains regulate the partition of the receptor into membrane raft microdomains

Mouse (Murine) Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

  1. both caveolin-1 and EMMPRIN mRNA levels increased gradually with progression of developmental stages, and peaked at day two postnatal. The current finding suggests that both caveolin-1 and EMMPRIN take part in mouse tooth development, especially in the differentiation and organization of odontogenic tissues.

  2. This study demonstrates, for the first time, that Cav-1 is expressed in developing periodontal tissue and in vitro in periodontal-related cells

  3. In vitro caveolin-1 silencing decreased the chondrocyte-like cell microaggregate glycosaminoglycan (GAG) content

  4. The results suggest that caveolin-1/TLR5 (show TLR5 Proteins) signaling plays a key role in age-associated innate immune responses and that FlaB (show FliC Proteins)-PspA (show SFTPA1 Proteins) stimulation of TLR5 (show TLR5 Proteins) may be a new strategy for a mucosal vaccine adjuvant against pneumococcal infection in the elderly.

  5. Cav-1 has a novel role in TCR/Lck spatial distribution upon TCR triggering, which controls T-cell fate toward a regulatory phenotype

  6. Data show that caveolin 1 (CAV1) is required for transforming growth factor-beta (TGF-beta)-induced reactive oxygen species production, mediated by NADPH oxidase (show NOX1 Proteins) NOX1 (show NOX1 Proteins), that is necessary for a disintegrin and metalloproteinase 17 (ADAM17 (show ADAM17 Proteins)) activation.

  7. physiologic adiponectin (show ADIPOQ Proteins) levels enhance the vasorelaxative response to acetylcholine by inducing nitric oxide production through AdipoR1 (show ADIPOR1 Proteins)/Cav-1 mediated signaling.

  8. results demonstrate that alterations in lipid rafts by the loss of parkin (show PARK2 Proteins) via cav-1 may be a causal factor of parties of disease

  9. Cav-1-dependent c-Fms (show CSF1R Proteins) stabilization contributes to efficient osteoclastogenesis.

  10. A novel role for intracellular caveolin-1 in modulating phagolysosomal function.

Human Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

  1. stromal caveolin-1 was associated with good prognostic parameters. Epithelial caveolin-1 is significantly increased in PCa (show FLVCR1 Proteins) than BPH (show GLI3 Proteins) and HGPIN. It is associated with clinically aggressive disease. Caveolin-1 may play a role in angiogenesis.

  2. loss of Cav-1 contributed to the imbalance of Th17/Treg cells in patients with COPD (show ARCN1 Proteins).

  3. Caveolin-1 is a sensitive Malignant mesothelioma marker and is expressed in a high proportion of cases but lacks association with histology and survival

  4. Data highlight that Caveolin 1 expression confers a proliferative advantage in lung adenocarcinoma cells, thus fostering increased tumor aggressiveness.

  5. low-expression of ARPC1B (show ARPC1B Proteins) is significantly associated with LNM and advanced tumor staging whereas high expression of Cav-1 can be a prognostic indicator for poor prognosis in OSCC patients.

  6. Cav-1 expression may be especially up-regulated in larger uveal melanomas. As it was correlated with PI3K (show PIK3CA Proteins) expression and vasculogenic mimicry (VM) in this series of uveal melanoma, Cav-1 might induce the formation of VM via the PI3K (show PIK3CA Proteins)-signalling cascade.

  7. caveolin-1 expression in cancer associated fibroblasts was significantly associated with a poor outcome in lung adenocarcinoma.

  8. Caveolin-1 affects ESCC MDR by regulating the expressions of P-gp (show ABCB4 Proteins) and MRP1 (show MDM4 Proteins).

  9. Triptolide represses the migration and invasion of prostate cancer cells through Cav-1/CD147 (show BSG Proteins)/MMPs signalling pathway.

  10. Cav-1 was inversely correlated with proliferation in PA.

Pig (Porcine) Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

  1. Caveolin-1 is a modulator of fibroblast activation and a potential biomarker for gastric cancer

  2. transcription factor Sp1 (show SP1 Proteins) interacts with nucleotides -123/-114, indicating that Sp1 (show SP1 Proteins) could play a key role in the transcriptional regulation of pig CAV-1

  3. Two alternative transcript variants encode two isoforms, caveolin-1-alpha and -beta; Cav1 may be implicated in pathogenesis of Glasser's disease of swine.

  4. The plasma membrane Na/K-ATPase (show ATP1A1 Proteins)-caveolin-1 interaction may represent an important sensing mechanism by which the cells regulate the sterol regulatory element-binding protein (show CNBP Proteins) pathway.

  5. The present study indicates that caveolin-containing rafts/caveolins such as caveolin-1 could play a modulating role during oligodendroglial differentiation and regeneration via NGF (show NGFB Proteins)/TrkA (show NTRK1 Proteins) signaling.

  6. Cav-1 might be a candidate gene for carcass traits, and might provide valuable information for understanding the mechanism of caveolae signaling in fat deposition by using the animal model of pig

Rabbit Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

  1. Caveolin-1 expression ameliorates nephrotic damage in a rabbit model of cholesterol-induced hypercholesterolemia.

  2. 8-Bromo-cAMP stimulated alpha-methyl-D-glucopyranoside uptake via Epac and PKA-dependent SGLTs expression and trafficking through cav-1 and F-actin in proximal tubule cells.

Cow (Bovine) Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

  1. Caveolin-1 scaffolding domain residue phenylalanine 92 modulates Akt (show AKT1 Proteins) signaling

  2. Data show that resveratrol (Res) reversed caveolin-1 (Cav-1)/endothelial nitric oxide synthase (eNOS (show NOS3 Proteins)) expressions in high glucose cultured bovine aortic endothelial cells (BAECs).

  3. these data provide the first detailed analysis of Cav-1 binding to one of its most significant client proteins, eNOS (show NOS3 Proteins).

  4. Study identifies a critical role of caveolin-1 in the regulation of eNOS (show NOS3 Proteins) uncoupling via a biopterin-dependent mechanism.

  5. Data indicate that caveolin-1 expression is required for insulin (show INS Proteins) uptake by aortic endothelial cells.

  6. caveolin-1 is not required for the targeting of signaling molecules to caveolae/lipid rafts

  7. integrin activation with shear stress results in SFK-regulated caveolin-1 phosphorylation that, in turn, mediates Csk (show CSK Proteins) association at integrin sites, where it plays a role in downstream, shear-stimulated myelin light chain diphosphorylation.

  8. importance of CAV1 amino acids 89-95 and particularly F92 in mediating eNOS (show NOS3 Proteins) inhibition by AP-Cav and Cav-1

  9. When endothelial cells were exposed to shear stress, caveolin-1 was transiently dephosphorylated.

  10. caveolin-1 tyrosine 14 phosphorylation has a role in cell adhesion and migration

Guinea Pig Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

  1. results suggest that cell division control protein 42(CDC42 (show CDC42 Proteins)) activation is favored by the disruption of the caveolin-1-CDC42 (show CDC42 Proteins) interaction, allowing for its participation in the regulation of capacitation and the acrosome reaction

Caenorhabditis elegans (C. elegans) Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

  1. The distribution of CAV-1 is highly dynamic during development and provides new insights into the sorting mechanisms that regulate CAV-1 localization.

Caveolin-1 (CAV1) Protein Profile

Protein Summary

The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.

Gene names and symbols associated with CAV1

  • caveolin 1 (cav1)
  • caveolin 1, caveolae protein, 22kDa (cav1-b)
  • caveolin 1, caveolae protein, 22kDa (cav1-a)
  • caveolin 1, caveolae protein, 22kDa (cav1)
  • caveolin 1, caveolae protein, 22kDa (CAV1)
  • caveolin 1 (CAV1)
  • caveolin 1, caveolae protein (Cav1)
  • caveolin 1, caveolae protein, 22kDa (Cav1)
  • Protein CAV-1 (cav-1)
  • BSCL3 protein
  • Cav protein
  • cav-1 protein
  • CAV1 protein
  • cav1a protein
  • cav1b protein
  • Caveolin-1 protein
  • caveolin 1 protein
  • CGL3 protein
  • fc07c04 protein
  • MSTP085 protein
  • PPH3 protein
  • VIP21 protein
  • wu:fc07c04 protein

Protein level used designations for CAV1

caveolin-1 , caveolin 1 , caveolin, caveolae protein 1 , caveolin, caveolae protein, 22 kDa , caveolin caveolae protein 22 kDa , vesicular integral-membrane protein VIP21 , cell growth-inhibiting protein 32 , testis derived transcript

GENE ID SPECIES
323695 Danio rerio
398392 Xenopus laevis
399006 Xenopus laevis
548467 Xenopus (Silurana) tropicalis
100126666 Papio anubis
100137140 Ornithorhynchus anatinus
100137154 Takifugu rubripes
12389 Mus musculus
25404 Rattus norvegicus
403980 Canis lupus familiaris
857 Homo sapiens
404693 Sus scrofa
100008837 Oryctolagus cuniculus
281040 Bos taurus
704449 Macaca mulatta
100055975 Equus caballus
373996 Gallus gallus
100718512 Cavia porcellus
493668 Felis catus
445468 Ovis aries
100860749 Capra hircus
100137027 Pongo abelii
463670 Pan troglodytes
100407940 Callithrix jacchus
177815 Caenorhabditis elegans
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