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Cbl-Interacting Protein Sts-1 Proteins (STS1)

STS1 encodes a protein that contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. Additionally we are shipping Cbl-Interacting Protein Sts-1 Antibodies (29) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
STS1 84959 Q8TF42
Mouse STS1 STS1 72828 Q8BGG7
Rat STS1 STS1 315579  
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Top Cbl-Interacting Protein Sts-1 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

STS1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

Top referenced Cbl-Interacting Protein Sts-1 Proteins

  1. Human STS1 Protein expressed in Escherichia coli (E. coli) - ABIN2005948 : Betz, Sadler: Variants of a cloned synthetic lactose operator. I. A palindromic dimer lactose operator derived from one stand of the cloned 40-base pair operator. in Gene 1981 (PubMed)

More Proteins for Cbl-Interacting Protein Sts-1 (STS1) Interaction Partners

Human Cbl-Interacting Protein Sts-1 (STS1) interaction partners

  1. The study reveals a role of CBL (show CBL Proteins) in restricting myeloid proliferation of human AML1 (show RUNX1 Proteins)-ETOinduced leukemia, and identifies UBASH3B as a potential target for pharmaceutical intervention.

  2. targeting Aurora B (show AURKB Proteins) to microtubules by UBASH3B is necessary for the timing and fidelity of chromosome segregation in human cells

  3. These results show that TULA-2 is a target of miR (show MLXIP Proteins)-148a-3p

  4. This recovery involves the phosphorylation of p70 (show ANXA6 Proteins) independent of mTOR (show FRAP1 Proteins).

  5. results demonstrate the importance of STS-1 in regulating IFN-alpha (show IFNA Proteins)-induced autophagy in B cells

  6. UBASH3B is a functional target of anti-invasive microRNA200a that is down-regulated in triple negative breast cancer. Importantly, the oncogenic potential of UBASH3B is dependent on its tyrosine phosphatase activity.

  7. Ablation of TULA-2 resulted in hyperphosphorylation of Syk (show SYK Proteins) and its downstream effector phospholipase C (show PLC Proteins)-gamma2 as well as enhanced GPVI (show GP6 Proteins)-mediated platelet functional responses.

  8. Sts-1 and Sts-2 (show UBASH3A Proteins) bind to Cbl (show CBL Proteins) and inhibit endocytosis of receptor tyrosine kinases

  9. hsp70 (show HSP70 Proteins) inhibits apoptosis upstream and downstream of the mitochondria and is a promising therapeutic target for reversing drug-resistance in chronic myeloid leukemia (show BCL11A Proteins)-blast crisis and acute myeloid leukemia (show BCL11A Proteins) cells.

  10. TULA (show UBASH3A Proteins) proteins TULA (show UBASH3A Proteins) and TULA-2 regulate activity of the protein tyrosine kinase (show EPHA8 Proteins) Syk (show SYK Proteins)

Mouse (Murine) Cbl-Interacting Protein Sts-1 (STS1) interaction partners

  1. Biochemical analysis identified STS-1 and STS-2 as direct phosphatases of FLT3 and c-KIT.

  2. results demonstrate the importance of STS-1 in regulating IFN-alpha (show IFNA Proteins)-induced autophagy in B cells.

  3. The lack of TULA-2 facilitates T-cell responses to TCR/CD3 (show CD3E Proteins) stimulation, thus exacerbating T-cell-dependent inflammation.

  4. TULA-2 negatively regulates osteoclast differentiation and function.

  5. Once phosphorylated, tyrosines in carboxyl terminus of protein-tyrosine kinase (show YES1 Proteins) Syk (show SYK Proteins) interact with signaling proteins, including TULA-2, a negative regulator of mast cell degranulation.

  6. Ablation of TULA-2 resulted in hyperphosphorylation of Syk (show SYK Proteins) and its downstream effector phospholipase C (show PLC Proteins)-gamma2 as well as enhanced GPVI (show GP6 Proteins)-mediated platelet functional responses.

  7. Syk (show SYK Proteins) is a bona fide TULA-2 substrate in platelets.

  8. Taken together, our data clearly demonstrate the ability of reversine to stimulate adipocyte differentiation, which is independent of the Akt (show AKT1 Proteins) and p70(s6k (show RPS6KB1 Proteins)) signaling pathways.

Cbl-Interacting Protein Sts-1 (STS1) Protein Profile

Protein Summary

This gene encodes a protein that contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. The encoded protein was found to inhibit endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor.

Gene names and symbols associated with STS1

  • ubiquitin associated and SH3 domain containing B (UBASH3B)
  • ubiquitin associated and SH3 domain containing, B (Ubash3b)
  • 2810457I06Rik protein
  • BB125008 protein
  • p70 protein
  • RGD1310357 protein
  • Sts-1 protein
  • STS1 protein
  • TULA-2 protein

Protein level used designations for STS1

Cbl-interacting protein Sts-1 , SH3 domain-containing 70 kDa protein, suppressor of T-cell receptor signaling 1, nm23-phosphorylated unknown substrate , T-cell ubiquitin ligand 2 , cbl-interacting protein p70 , nm23-phosphorylated unknown substrate , suppressor of T-cell receptor signaling 1 , tyrosine-protein phosphatase STS1/TULA2 , ubiquitin-associated and SH3 domain-containing protein B , STS-1

GENE ID SPECIES
84959 Homo sapiens
72828 Mus musculus
315579 Rattus norvegicus
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