UBASH3B Protein (AA 380-649) (His tag)
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- Target See all UBASH3B (STS1) Proteins
- UBASH3B (STS1) (Cbl-Interacting Protein Sts-1 (STS1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 380-649
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This UBASH3B protein is labelled with His tag.
- Purpose
- Human UBASH3B/STS1 Protein
- Sequence
- Gly380-Glu649
- Characteristics
- Recombinant Human UBASH3B/STS1 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Gly380-Glu649.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- UBASH3B (STS1) (Cbl-Interacting Protein Sts-1 (STS1))
- Alternative Name
- UBASH3B (STS1 Products)
- Synonyms
- STS-1 Protein, STS1 Protein, TULA-2 Protein, p70 Protein, 2810457I06Rik Protein, BB125008 Protein, RGD1310357 Protein, Sts-1 Protein, ubiquitin associated and SH3 domain containing B Protein, ubiquitin associated and SH3 domain containing, B Protein, UBASH3B Protein, Ubash3b Protein
- Background
- UBASH3/STS/TULA is a novel two-member family, which exerts several key regulatory effects in multiple cell types. UBASH3B/STS-1/TULA-2 is a highly active protein tyrosine phosphatase, its major target appears to be a specific regulatory site of protein tyrosine kinases of the Syk family, dephosphorylation of which inhibits Syk and Zap-70 kinases and suppresses receptor signaling mediated by these kinases.
- Molecular Weight
- 31.88 kDa same as Tris-Bis PAGE result.
- UniProt
- Q8TF42
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