anti-ChaC, Cation Transport Regulator Homolog 1 (E. Coli) (CHAC1) Antibodies

Negative regulator of Notch signaling pathway involved furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in embryos. Additionally we are shipping CHAC1 Proteins (5) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CHAC1 69065 Q8R3J5
CHAC1 79094 Q9BUX1
CHAC1 362196 B3STU3
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Top anti-CHAC1 Antibodies at antibodies-online.com

Showing 10 out of 48 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: CHAC1 Sample Tissue: Human RPMI 8226 Whole Cell Antibody Dilution: 1ug/ml WB Suggested Anti-CHAC1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: 721_B cell lysate CHAC1 is supported by BioGPS gene expression data to be expressed in 721_B 100 μL Log in to see 2 to 3 Days
$289.00
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti CHAC1 Polyclonal Antibody, Unconjugated (ABIN872557) at 1:200 followed by conjugation to the secondary antibody and DAB staining Lane 1: mouse brain lysates Lane 2: mouse kidney lysates probed with Anti CHAC1 Polyclonal Antibody, Unconjugated (ABIN872557) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 24kD. Observed band size: 24kD. 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Mouse Un-conjugated IF, IHC, WB Immunohistochemistry: CHAC1 Antibody (1E2) [NBP2-46273] - Analysis of Adenocarcinoma of Human colon tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) Immunohistochemistry: CHAC1 Antibody (1E2) [NBP2-46273] - Analysis of Adenocarcinoma of Human endometrium tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Un-conjugated WB Western blot analysis of CHAC1 expression in U2OS (A), HeLa (B), Raw264.7 (C), PC12 (D) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Cy5.5 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

CHAC1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CHAC1 Antibodies

  1. Mammalian Monoclonal CHAC1 Primary Antibody for ISt, IHC - ABIN1304563 : Chi, Zhang, Tokunaga, Harraz, Byrne, Dolinko, Xu, Blackshaw, Gaiano, Dawson, Dawson: Botch promotes neurogenesis by antagonizing Notch. in Developmental cell 2012 (PubMed)
    Show all 2 Pubmed References

  2. Cow (Bovine) Polyclonal CHAC1 Primary Antibody for WB - ABIN2773808 : Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ... in Genome research 2004 (PubMed)
    Show all 2 Pubmed References

More Antibodies against CHAC1 Interaction Partners

Mouse (Murine) ChaC, Cation Transport Regulator Homolog 1 (E. Coli) (CHAC1) interaction partners

  1. Chac1 expression is detrimental to arsenite-treated cell survival and TRIB3 (show TRIB3 Antibodies) is critical for restraining the pro-death potential of Chac1 during arsenite stress.

  2. Data indicate that Chac1 protein expression was only detected in the presence of MG132, a proteasome inhibitor.

  3. The ChaC family is conversed across all phyla and represents a new pathway for glutathione degradation in living cells, and the first cytosolic pathway for glutathione degradation in mammalian cells.

Human ChaC, Cation Transport Regulator Homolog 1 (E. Coli) (CHAC1) interaction partners

  1. Human CHAC1 Protein Degrades Glutathione, and mRNA Induction Is Regulated by the Transcription Factors ATF4 (show ATF4 Antibodies) and ATF3 (show ATF3 Antibodies) and a Bipartite ATF/CRE Regulatory Element.

  2. Botch regulates Notch (show NOTCH1 Antibodies) signaling through deglycination and identify a posttranslational modification of Notch (show NOTCH1 Antibodies) that plays an important role in neurogenesis.

  3. nisin exerts these effects on HNSCC, in part, through CHAC1, a proapoptotic cation transport regulator, and through a concomitant CHAC1-independent influx of extracellular calcium

  4. High CHAC1 mRNA expression could be an independent indicator for elevated risk of cancer recurrence in breast and ovarian cancer

CHAC1 Antigen Profile

Protein Summary

Negative regulator of Notch signaling pathway involved furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in embryos. May also act as a pro-apoptotic component of the unfolded protein response pathway by mediating the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade (By similarity).

Gene names and symbols associated with CHAC1

  • ChaC, cation transport regulator homolog 1 (E. coli) (CHAC1) antibody
  • ChaC, cation transport regulator homolog 1 (E. coli) (LOC100219118) antibody
  • ChaC, cation transport regulator 1 (Chac1) antibody
  • ChaC, cation transport regulator homolog 1 (E. coli) (Chac1) antibody
  • 1810008K03Rik antibody
  • RGD1307153 antibody

Protein level used designations for CHAC1

cation transport regulator-like protein 1 , ChaC, cation transport regulator-like 1 , ChaC, cation transport regulator homolog 1 (E. coli) , blocks Notch protein , botch , cation transport regulator homolog 1 , neuroprotective protein 7

GENE ID SPECIES
423209 Gallus gallus
467659 Pan troglodytes
705007 Macaca mulatta
100219118 Taeniopygia guttata
69065 Mus musculus
79094 Homo sapiens
487504 Canis lupus familiaris
505991 Bos taurus
362196 Rattus norvegicus
Selected quality suppliers for anti-CHAC1 (CHAC1) Antibodies
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