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CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. Additionally we are shipping and many more products for this protein.
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Human Polyclonal CHMP1B Primary Antibody for ELISA, WB - ABIN566093
Yang, Rismanchi, Renvoisé, Lippincott-Schwartz, Blackstone, Hurley: Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B. in Nature structural & molecular biology 2008
Show all 2 references for ABIN566093
The interaction between CL7MIT and CHMP1B and between CL7MIT and IST1 (show IST1 Antibodies) became stronger when IST1 (show IST1 Antibodies) or CHMP1B was additionally coexpressed, suggesting formation of ternary complex of calpain-7 (show CAPN7 Antibodies), IST1 (show IST1 Antibodies) and CHMP1B.
CHMP1B is bound by the VPS4A (show VPS4A Antibodies) microtubule interacting and transport (MIT) domain.
UBPY (show USP8 Antibodies) MIT domain and another ubiquitin isopeptidase, AMSH (show STAMBP Antibodies), reveals common interactions with CHMP1A (show CHMP1A Antibodies) and CHMP1B but a distinct selectivity of AMSH (show STAMBP Antibodies) for CHMP3/VPS24 (show CHMP3 Antibodies), a core subunit of the ESCRT-III complex, and UBPY (show USP8 Antibodies) for CHMP7 (show CHMP7 Antibodies).
The 2.5-A structure of the C-terminal tail of CHMP1B with the MIT domain of spastin (show SPAST Antibodies) reveals a specific, high-affinity complex involving a noncanonical binding site between the first and third helices of the MIT domain.
CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006
chromatin modifying protein 1b
, chromatin modifying protein 1B
, charged multivesicular body protein 1b
, chromatin-modifying protein 1b
, vacuolar protein sorting 46-2
, vacuolar protein sorting-associated protein 46-2
, charged multivesicular body protein 1b-1
, chromatin-modifying protein 1b-1