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Chemokine (C-C Motif) Ligand 27 Proteins (CCL27)

CCL27 is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Additionally we are shipping CCL27 Kits (53) and CCL27 Antibodies (50) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat CCL27 CCL27 362505  
CCL27 10850 Q9Y4X3
CCL27 20301 Q9Z1X0
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Top CCL27 Proteins at antibodies-online.com

Showing 10 out of 33 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 16 Days
$272.80
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 10 to 12 Days
$135.88
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 7 to 8 Days
$286.00
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   50 μg Log in to see 2 to 3 Days
$630.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 7 to 9 Days
$328.21
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   20 μg Log in to see 7 to 9 Days
$328.21
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   1 mg Log in to see 2 to 3 Days
$3,648.75
Details

CCL27 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Top referenced CCL27 Proteins

  1. Human CCL27 Protein expressed in Escherichia coli (E. coli) - ABIN2666614 : Kai, Kadono, Kakinuma, Tomita, Ohmatsu, Asano, Tada, Sugaya, Sato: CCR10 and CCL27 are overexpressed in cutaneous squamous cell carcinoma. in Pathology, research and practice 2010 (PubMed)
    Show all 6 references for ABIN2666614

  2. Human CCL27 Protein expressed in Escherichia coli (E. coli) - ABIN2003159 : Morales, Homey, Vicari, Hudak, Oldham, Hedrick, Orozco, Copeland, Jenkins, McEvoy, Zlotnik: CTACK, a skin-associated chemokine that preferentially attracts skin-homing memory T cells. in Proceedings of the National Academy of Sciences of the United States of America 2000 (PubMed)
    Show all 4 references for ABIN2003159

  3. Human CCL27 Protein expressed in Escherichia coli (E. coli) - ABIN666971 : Kanda, Watanabe: Leukotriene B(4) enhances tumour necrosis factor-alpha-induced CCL27 production in human keratinocytes. in Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2007 (PubMed)
    Show all 2 references for ABIN666971

More Proteins for Chemokine (C-C Motif) Ligand 27 (CCL27) Interaction Partners

Human Chemokine (C-C Motif) Ligand 27 (CCL27) interaction partners

  1. Our data supports previous reports showing IL-17 (show IL17A Proteins) and -23 upregulation in association with Multiple sclerosis and potentially identify a previously unknown involvement for CCL27.

  2. NOS2 (show NANOS2 Proteins) and CCL27: clinical implications for psoriasis and eczema diagnosis and management.

  3. Findings support the notion that CCR10 (show CCR10 Proteins) and its ligand CCL27 may contribute to the skin infiltration of malignant T-cells in mycosis fungoides and adult T-cell leukemia/lymphoma.

  4. Our study suggests that CTACK/CCL27 may have a pivotal role in the early stage of psoriasis plaque formation, but should be downregulated in the later stage to induce inflammation characteristic for chronic psoriasis plaques

  5. Seventeen mediators were identified in burn wound exudates (concentration range 0.0006-9 ng/mg total protein), including the skin-specific chemokine (show CCL1 Proteins) CCL27.

  6. We show that the adult but not prenatal human keratinocytes produce and release large amounts of CCL27.

  7. CCL27 chemokine (show CCL1 Proteins) implicates cholesteatoma keratinocytes as contributors in cholesteatoma progression.

  8. low CCL27/CCR10 (show CCR10 Proteins) and CXCL12 (show CXCL12 Proteins)/CXCR4 (show CXCR4 Proteins) intratumoral mRNA ratios are associated with melanoma progression

  9. Serum concentrations of TARC (show CCL17 Proteins) and CTACK were significantly higher in AD (atopic dermatitis) children than in healthy controls, and correlated with severity of symptoms.

  10. IL-1beta (show IL1B Proteins)-induced CCL27 gene expression in normal human keratinocytes is regulated through the p38 MAPK (show MAPK14 Proteins)/MSK1 (show RPS6KA5 Proteins)/Mnk1 (show MKNK1 Proteins)+2 as well as the IKKbeta (show IKBKB Proteins)/NF-kappaB (show NFKB1 Proteins) signalling pathways.

Mouse (Murine) Chemokine (C-C Motif) Ligand 27 (CCL27) interaction partners

  1. Our in vivo analysis demonstrated that uniform expression of Ccr10 (show CCR10 Proteins) on MSCs and alteration of Ccl27 level in the skin enhance extravasation of stem cells from circulation and facilitate their migration within cutaneous tissue

  2. We investigated the role of CCL27, a T cell skin-homing chemokine (show CCL1 Proteins) known to be elevated in sera of human AD patients, in disease development in our animal model of atopic dermatitis.

  3. LIGHT stimulation enhances CCL27 expression through activation of NF-kappaB (show NFKB1 Proteins) in DCs.

  4. In mice, neutralization of CCL27 led to decreased leukocyte recruitment to cutaneous tumor sites and significantly enhanced primary tumor growth.

  5. Results indicated that CCL27 modified inflammation by attracting CCR10 (show CCR10 Proteins)-positive and CCR4 (show CCR4 Proteins)-positive cells into the lesional skin, and may participate in the pathogenesis of Th2-shifted skin diseases such as atopic dermatitis.

CCL27 Protein Profile

Protein Summary

This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation.

Gene names and symbols associated with CCL27

  • chemokine (C-C motif) ligand 27 (Ccl27)
  • chemokine (C-C motif) ligand 27 (CCL27)
  • uncharacterized LOC508933 (LOC508933)
  • chemokine (C-C motif) ligand 27A (Ccl27a)
  • ALP protein
  • AW558992 protein
  • Ccl27 protein
  • CTACK protein
  • CTAK protein
  • ESKINE protein
  • ILC protein
  • PESKY protein
  • Scya27 protein
  • Scya27a protein

Protein level used designations for CCL27

chemokine (C-C motif) ligand 27 , C-C motif chemokine 27 , skinkine , chemokine CCL27/CTACK , CC chemokine ILC , IL-11 R-alpha-locus chemokine , IL-11 Ralpha-locus chemokine , cutaneous T-cell attracting chemokine , cutaneous T-cell-attracting chemokine , small inducible cytokine subfamily A (Cys-Cys), member 27 , small-inducible cytokine A27 , cutaneous T cell attracting chemokine , hemokine (C-C motif) ligand 27 , skinskine , small inducible cytokine A27 , small inducible cytokine A27a

GENE ID SPECIES
362505 Rattus norvegicus
445453 Sus scrofa
508933 Bos taurus
574220 Macaca mulatta
10850 Homo sapiens
445454 Canis lupus familiaris
20301 Mus musculus
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