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CCR8 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Additionally we are shipping CCR8 Kits (8) and CCR8 Proteins (4) and many more products for this protein.
Showing 10 out of 132 products:
Human Polyclonal CCR8 Primary Antibody for EIA, FACS - ABIN951452
Mutalithas, Guillen, Raport, Kolbeck, Soler, Brightling, Pavord, Wardlaw: Expression of CCR8 is increased in asthma. in Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2010
Show all 5 references for ABIN951452
Human Monoclonal CCR8 Primary Antibody for FACS - ABIN2662408
Tiffany, Lautens, Gao, Pease, Locati, Combadiere, Modi, Bonner, Murphy: Identification of CCR8: a human monocyte and thymus receptor for the CC chemokine I-309. in The Journal of experimental medicine 1997
Show all 5 references for ABIN2662408
Mouse (Murine) Polyclonal CCR8 Primary Antibody for IHC (p), IHC - ABIN152132
Liu, Cao, Tang, Liu, Tang: CCR7, CCR8, CCR9 and CCR10 in the mouse hippocampal CA1 area and the dentate gyrus during and after pilocarpine-induced status epilepticus. in Journal of neurochemistry 2007
Show all 2 references for ABIN152132
Human Polyclonal CCR8 Primary Antibody for WB - ABIN319016
Goya, Gutiérrez, Varona, Kremer, Zaballos, Márquez: Identification of CCR8 as the specific receptor for the human beta-chemokine I-309: cloning and molecular characterization of murine CCR8 as the receptor for TCA-3. in Journal of immunology (Baltimore, Md. : 1950) 1998
Cow (Bovine) Polyclonal CCR8 Primary Antibody for WB - ABIN2792241
Haque, Fallon, Pan, Taubman, Harpel: Chemokine receptor-8 (CCR8) mediates human vascular smooth muscle cell chemotaxis and metalloproteinase-2 secretion. in Blood 2004
High CCR8 expression is associated with high recurrence in kidney cancer.
findings suggest that CCR8 expression in ALCL is more closely related to the presence of DUSP22 (show DUSP22 Antibodies) rearrangements than to cutaneous involvement and that the function of CCR8 may extend beyond its skin-homing properties in this disease
Epidermal-derived vitamin D3 metabolites and prostaglandins provide an essential cue for the localization of CCR8+ immune surveillance T cells within healthy human skin.
CCL1 (show CCL1 Antibodies)-CCR8 interaction may play a critical role in lymphocytic recruitment in IgG4-related sclerosing cholangitis and type 1 autoimmune pancreatitis, leading to duct-centred inflammation and obliterative phlebitis.
Identification of human CCR8 as a CCL18 (show CCL18 Antibodies) receptor.
CCR8(+) myeloid cell subset is expanded in patients with cancer.
Data show that CCR8 expression by newly activated naive T cells is regulated by skin-specific factor(s) derived primarily from epidermal keratinocytes.
C-terminal clipping of chemokine CCL1 (show CCL1 Antibodies)/I-309 enhances CCR8-mediated intracellular calcium release and anti-apoptotic activity
The functional data from human macrophages suggest a potential cross talk between the CCR8 and the Toll-like receptor 4 (TLR4 (show TLR4 Antibodies)) pathways, both of which are present in chronic obstructive pulmonary disease patients.
There may be a role for CCR8 in the recruitment of T cells to the lung in asthmatics.
CCR8 negatively regulates migration of cutaneous dendritic cells from the skin to the draining lymph nodes in contact hypersensitivity by keeping these cells in the skin.
Chemokine receptor (show CCR1 Antibodies) CCR8 is required for lipopolysaccharide-triggered cytokine production in mouse peritoneal macrophages.
A sustained donor Treg presence is critical for their beneficial properties, and that their survival depends on CCR8 and donor but not host CD11c (show ITGAX Antibodies)(+) Aantigen presenting cells.
Expression of CCR-8 in microglia was upregulated in the presence of CCL-1 (show CCL1 Antibodies).
Hepatic macrophage migration and differentiation critical for liver fibrosis is mediated by the chemokine receptor (show CCR1 Antibodies) C-C motif chemokine receptor 8 in mice.
a key regulator of Th2 cell skin recruitment during IL-5 (show IL5 Antibodies)-mediated allergic inflammation
mediates increased responsiveness of murine eosinophils to TCA-3 (show CCL1 Antibodies)
Data from three different models plus an in vivo blocking study clearly show that the Th2 cell-mediated pathological response to ovalbumin (show OVA Antibodies)-induced allergic airway inflammation is not critically CCR8-dependent.
sulfation at specific positions of the N-terminal domain of mouse CCR8 is critical for its biological activity, whereas glycosylation has a minor influence
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region.
chemokine (C-C motif) receptor 8
, C-C chemokine receptor type 8
, CC chemokine receptor 8
, CC chemokine receptor CHEMR1
, CC-chemokine receptor chemr1
, chemokine (C-C) receptor 8
, chemokine (C-C) receptor-like 2
, chemokine receptor-like 1
, C-C motif chemokine receptor 8