CCR8 Products
(Chemokine (C-C Motif) Receptor 8 (CCR8))
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This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq, Jul 2008].
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Featured CCR8 Categories
CCR8 Antibodies
High quality antibodies with extensive validation data.
CCR8 ELISA Kits
Reliable ELISA kits for a wide range of species.
CCR8 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CCR8 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN2854720
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN7101661
Quantity
20 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS
Validations
- (2)
Cat. No.
ABIN654442
Quantity
400 μL
Datasheet
Datasheet
Recommended CCR8 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965716
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1114080
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN510069
Quantity
96 tests
Datasheet
Datasheet
Recommended CCR8 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274054
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274053
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348500
Quantity
25 μg
Datasheet
Datasheet
Latest Publications for our CCR8 products
: "CC Chemokine Ligand 18 in ANCA-Associated Crescentic GN." in: Journal of the American Society of Nephrology : JASN, Vol. 26, Issue 9, pp. 2105-17, (2015) (PubMed).: "Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 6, pp. 2886-98, (2010) (PubMed).
: "CD56highCD16-CD62L- NK cells accumulate in allergic contact dermatitis and contribute to the expression of allergic responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 2, pp. 1102-10, (2010) (PubMed).
: "Chemokine-enhanced chemotaxis of lymphangioleiomyomatosis cells with mutations in the tumor suppressor TSC2 gene." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 3, pp. 1270-7, (2009) (PubMed).
: "Chemokine responsiveness of CD4+ CD25+ regulatory and CD4+ CD25- T cells from atopic and nonatopic donors." in: Allergy, Vol. 64, Issue 8, pp. 1121-9, (2009) (PubMed).
: "Chemokine-mediated migration of skin-derived stem cells: predominant role for CCL5/RANTES." in: The Journal of investigative dermatology, Vol. 129, Issue 6, pp. 1569-81, (2009) (PubMed).
: "CCR7, CCR8, CCR9 and CCR10 in the mouse hippocampal CA1 area and the dentate gyrus during and after pilocarpine-induced status epilepticus." in: Journal of neurochemistry, Vol. 100, Issue 4, pp. 1072-88, (2007) (PubMed).
: "Down-modulation of CXCR3 surface expression and function in CD8+ T cells from cutaneous T cell lymphoma patients." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 6, pp. 4272-82, (2007) (PubMed).
: "Human dendritic cells acquire a semimature phenotype and lymph node homing potential through interaction with CD4+CD25+ regulatory T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 7, pp. 4184-93, (2007) (PubMed).
: "Chemokine receptor-8 (CCR8) mediates human vascular smooth muscle cell chemotaxis and metalloproteinase-2 secretion." in: Blood, Vol. 103, Issue 4, pp. 1296-304, (2004) (PubMed).
Synonyms and alternative names related to CCR8
C-C motif chemokine receptor 8 (CCR8), chemokine (C-C motif) receptor 8 (Ccr8), C-C motif chemokine receptor 8 (Ccr8), C-C, C-C CKR-8, CC-CKR-8, CCR-8, CDw198, CKR-8, CKRL1, CMKBR8, Cmkbr8, CMKBRL2, CY6, GPRCY6, mCCR8, TER1Protein level used designations for CCR8
- C-C chemokine receptor type 8
- CC chemokine receptor 8
- CC chemokine receptor CHEMR1
- CC-chemokine receptor chemr1
- chemokine (C-C) receptor 8
- chemokine (C-C) receptor-like 2
- chemokine receptor-like 1
- C-C motif chemokine receptor 8
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