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anti-Chimerin (Chimaerin) 2 (CHN2) Antibodies

CHN2 is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. Additionally we are shipping Chimerin (Chimaerin) 2 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CHN2 69993 Q80XD1
CHN2 1124 P52757
CHN2 84031 Q03070
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Top anti-Chimerin (Chimaerin) 2 Antibodies at antibodies-online.com

Showing 10 out of 48 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-CHN2 Antibody Titration: 0.2-1 ug/mlPositive Control: Human Liver 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-CHN2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human Thymus 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of CHN2 Antibody (Center) (ABIN653442) in Hela cell line lysates (35 µg/lane). CHN2 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of CHN2 Antibody (Center) (ABIN653442) in mouse liver tissue lysates (35 µg/lane). CHN2 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of CHN2 (arrow) in Hela cell line lysates (35ug/lane) using ARHGAP3/CHN2  Western blot analysis of CHN2 (arrow) in mouse liver tissue lysates (35ug/lane) using ARHGAP3/CHN2  0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Goat Un-conjugated EIA, IHC (p) 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated ELISA   0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated IHC, ELISA, WB   100 μg Log in to see 4 to 5 Days
$318.20
Details

CHN2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) , , ,
,

Human , , ,
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Rat (Rattus) ,
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Top referenced anti-Chimerin (Chimaerin) 2 Antibodies

  1. Human Polyclonal CHN2 Primary Antibody for EIA, WB - ABIN492870 : Ridley: Cyclin' round the cell with Rac. in Developmental cell 2001 (PubMed)
    Show all 3 references for ABIN492870

  2. Human Polyclonal CHN2 Primary Antibody for WB - ABIN653442 : Takefuji, Asano, Mori, Amano, Kato, Watanabe, Morita, Katsumi, Itoh, Takenawa, Hirashiki, Izawa, Nagata, Hirayama, Takatsu, Naoe, Yokota, Kaibuchi: Mutation of ARHGAP9 in patients with coronary spastic angina. in Journal of human genetics 2010 (PubMed)
    Show all 3 references for ABIN653442

  3. Human Polyclonal CHN2 Primary Antibody for EIA, WB - ABIN950491 : Suliman, Stanik, McCulloch, Wilson, Edghill, Misovicova, Gasperikova, Sandrikova, Elliott, Barak, Ellard, Volpi, Klimes, Gloyn: Severe insulin resistance and intrauterine growth deficiency associated with haploinsufficiency for INSR and CHN2: new insights into synergistic pathways involved in growth and metabolism. in Diabetes 2009 (PubMed)
    Show all 3 references for ABIN950491

  4. Chicken Polyclonal CHN2 Primary Antibody for WB - ABIN2784666 : Uhl, Liu, Drgon, Johnson, Walther, Rose, David, Niaura, Lerman: Molecular genetics of successful smoking cessation: convergent genome-wide association study results. in Archives of general psychiatry 2008 (PubMed)

More Antibodies against Chimerin (Chimaerin) 2 Interaction Partners

Mouse (Murine) Chimerin (Chimaerin) 2 (CHN2) interaction partners

  1. Study demonstrates that Sema3F (show SEMA3F Antibodies)-dependent inhibition of Rac1 by the Rac (show AKT1 Antibodies)-GAP beta2Chn is required for hippocampal infrapyramidal tract pruning.

  2. the Rac-GAP beta2-chimaerin is negatively regulated by protein kinase Cdelta-mediated phosphorylation

Human Chimerin (Chimaerin) 2 (CHN2) interaction partners

  1. CHN2 is consistently hypermethylated and downregulated in small bowel adenocarcinoma with diagnostic potential

  2. CHN2, ABCB1 (show ABCB1 Antibodies) and PPP1R9A (show PPP1R9A Antibodies) expression on chromosome 7 is implicated in the pathogenesis of hepatosplenic T-cell lymphoma distinguishing it from other malignancies.

  3. genetic association studies in a population in Taiwan: Data suggest that an SNP in CHN2 (rs1002630) is associated with non-proliferative diabetic retinopathy in patients with diabetes type 2 in the Han Chinese population studied.

  4. A significant association of the novel rs186911567 polymorphism was found for the CHN2 gene with smoking.

  5. genetic association studies in a Chinese population with type 2 diabetes: An SNP in CHN2 (rs39059) is associated with diabetic retinopathy in a Chinese population of type 2 diabetic patients.

  6. the Rac-GAP beta2-chimaerin is negatively regulated by protein kinase Cdelta-mediated phosphorylation

  7. beta 2 chimerin has a role in rac (show AKT1 Antibodies)-GAP-dependent inhibition of breast cancer cell proliferation

  8. Data demonstrate that beta2-chimaerin (show CHN1 Antibodies) provides a novel, diacylglycerol-dependent mechanism for Rac (show AKT1 Antibodies) regulation in T cells and suggest a functional role for this protein in Rac (show AKT1 Antibodies)-mediated cytoskeletal remodeling.

  9. Beta2-chimaerin (show CHN1 Antibodies) regulates the proliferation and migration of vascular smooth muscle cells downstream of growth factor signaling pathway implicating human atherogenesis.

  10. results suggest Tyr (show TYR Antibodies)-21 phosphorylation of beta2-chimaerin (show CHN1 Antibodies) as a novel, Src (show SRC Antibodies)-family kinase-dependent mechanism that negatively regulates beta2-chimaerin (show CHN1 Antibodies) Rac (show AKT1 Antibodies)-GAP activity

Chimerin (Chimaerin) 2 (CHN2) Antigen Profile

Protein Summary

This gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with CHN2

  • chimerin (chimaerin) 2 (chn2) antibody
  • beta chimerin (LOC100344407) antibody
  • chimerin (chimaerin) 2 (CHN2) antibody
  • chimerin 2 (CHN2) antibody
  • chimerin (chimaerin) 2 (Chn2) antibody
  • chimerin 2 (chn2) antibody
  • chimerin 2 (Chn2) antibody
  • 1700026N20Rik antibody
  • 4930557O16Rik antibody
  • ARHGAP3 antibody
  • BCH antibody
  • CHN2-3 antibody
  • RHOGAP3 antibody

Protein level used designations for CHN2

beta chimerin , chimerin (chimaerin) 2 , beta-chimaerin-like , beta-chimaerin , Rho GTPase-activating protein 3 , beta chimaerin , beta-chimerin , beta3-chimaerin , chimaerin 2 , rho-GTPase-activating protein 3 , rho GTPase-activating protein 3

GENE ID SPECIES
570999 Danio rerio
100344407 Oryctolagus cuniculus
472333 Pan troglodytes
475267 Canis lupus familiaris
697231 Macaca mulatta
100032581 Monodelphis domestica
100392207 Callithrix jacchus
100451463 Pongo abelii
100468141 Ailuropoda melanoleuca
100496459 Xenopus (Silurana) tropicalis
100541305 Meleagris gallopavo
100567151 Anolis carolinensis
100596099 Nomascus leucogenys
428437 Gallus gallus
507285 Bos taurus
69993 Mus musculus
444340 Xenopus laevis
1124 Homo sapiens
84031 Rattus norvegicus
Selected quality suppliers for anti-Chimerin (Chimaerin) 2 (CHN2) Antibodies
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