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May be involved in mediating calcium-activated chloride conductance. Additionally we are shipping and many more products for this protein.
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Clca1 (show CLCA1 Antibodies) is not required for mucus synthesis, structure and barrier function in the murine colon.
mCLCA3 appears to modulate leukocyte response via IL-17 (show IL17A Antibodies) and murine CXCL-8 (show IL8 Antibodies) homologs in acute Staphylococcus aureus pneumonia which is well in line with the proposed function of hCLCA1 (show CLCA1 Antibodies) as a signaling molecule acting on alveolar macrophages.
Findings suggest that increased expression of a single-gene, mCLCA3, could simulate an asthma attack, and its mechanism may involve mCLCA3 overexpression up-regulating IL-13 (show IL13 Antibodies) expression.
PA-LPS (show TLR4 Antibodies)-induced MUC5AC and Clca3 expression is partly through Duox1 (show DUOX1 Antibodies)
these findings argue against a role of mCLCA3 in Ca(2 (show CA2 Antibodies) )-activated Cl(-) channel-mediated Cl(-) secretion in murine respiratory epithelia
a functional link between two distinct anion currents, ClC-3 (show CLCN3 Antibodies) and swelling-activated chloride current
conclude that hCLCA1 (show CLCA1 Antibodies) and mCLCA3 are non-integral membrane proteins and therefore cannot be chloride channels in their own right
Gob-5 (show CLCA1 Antibodies) expression is not essential for mucin (show SLC13A2 Antibodies) overproduction in vitro or in murine models of allergic asthma
We found that mClCA3 expression was significantly decreased in the colon and lung of the cftr (show CFTR Antibodies)-/- mice.
These observations reinforce findings that associate Gob-5 (show CLCA1 Antibodies) with goblet cell hyperplasia and mucus production in the allergic immune response, but also implicate Gob-5 (show CLCA1 Antibodies) in the regulation of tissue inflammation in the innate immune response.
May be involved in mediating calcium-activated chloride conductance. May play critical roles in goblet cell metaplasia, mucus hypersecretion, cystic fibrosis and AHR. May be involved in the regulation of mucus production and/or secretion by goblet cells. Involved in the regulation of tissue inflammation in the innate immune response. May play a role as a tumor suppressor. Induces MUC5AC.
calcium-activated chloride channel regulator 1
, chloride channel calcium activated 3
, calcium-activated chloride channel family member 3
, chloride channel calcium activated 2
, protein gob-5