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Chromatin Assembly Factor 1, Subunit A (p150) Proteins (CHAF1A)

Chromatin assembly factor I (CAF1) is a nuclear complex consisting of p50, p60 (CHAF1B\; MIM 601245), and p150 (CHAF1A) subunits that assembles histone octamers onto replicating DNA in vitro (Kaufman et al., 1995 [PubMed 7600578]).[supplied by OMIM, Mar 2008].. Additionally we are shipping CHAF1A Antibodies (54) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat CHAF1A CHAF1A 363333  
CHAF1A 10036 Q13111
CHAF1A 27221 Q9QWF0
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Top CHAF1A Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CHAF1A Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Top referenced CHAF1A Proteins

  1. Human CHAF1A Protein expressed in Wheat germ - ABIN1349272 : Doe, Nozawa, Hiruma, Yamada, Matsuki, Nakano, Ogasawara, Nakano, Ikeda, Ikegami, Fujishiro, Kawasaki, Ikeda, Amano, Morimoto, Ogawa, Takamori, Sekigawa, Takasaki: Antibody against chromatin assembly factor-1 is a novel autoantibody specifically recognized in systemic lupus erythematosus. in Lupus 2014 (PubMed)

More Proteins for Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A) Interaction Partners

Human Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A) interaction partners

  1. Taken together, these results show that CHAF1A contributes to the proliferation of glioblastoma cells and may be developed as a de novo drug target and prognosis biomarker of glioblastoma.

  2. Novel functions for a separable domain of the p150 protein, regulating protein and DNA interactions at the nucleolus.

  3. The frequency of positive CHAF1A staining in primary tumor mucosa (45.8% of 203 samples) was significantly elevated compared to normal mucosa (18.7% of samples). Increased expression was associated with cancer stage, tumor invasion and histological grade.

  4. Histone chaperone CHAF1A inhibits differentiation and promotes aggressive neuroblastoma (show ARHGEF16 Proteins).

  5. CAF1 was hijacked by IE2 to facilitate the replication of the HCMV genome, suggesting chromatin assembly plays an important role in herpesviral DNA synthesis, but also provide a model of the virus-induced chromatin instability through CAF1.

  6. CAF (show KAT2B Proteins)-I-dependent control of degradation of the discontinuous strands during mismatch repair.

  7. these findings suggest an expanded role of p150 (show ABL1 Proteins) as a SUMO2 (show SUMO2 Proteins)/3-interacting factor, and raise the intriguing possibility that p150 (show ABL1 Proteins) plays a role in promoting delivery of SUMO2 (show SUMO2 Proteins)/3 or SUMO2 (show SUMO2 Proteins)/3-modified proteins (or both) on chromatin fibers during replication.

  8. p150 (show ABL1 Proteins) was efficiently phosphorylated by Cdc7 (show CDC7 Proteins)-Dbf4 (show DBF4 Proteins) kinase.

  9. ACF (show A1CF Proteins) generates the characteristic 50- to 60-base-pair internucleosomal spacing in silent chromatin by kinetically discriminating against shorter linker DNAs

  10. rs9352 of CHAF1A was repeatedly includes (78% of the 200 bootstrap samples) in the best set of SNPs. CHAF1A may contribute to gliomagenesis.

Mouse (Murine) Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A) interaction partners

  1. CAF-1 (show CNOT7 Proteins) is an essential guardian of the genome in preimplantation mouse embryos.

  2. the histone chaperone CAF-1 (show CNOT7 Proteins) to be a novel regulator of somatic cell identity during transcription-factor-induced cell-fate transitions and provide a potential strategy to modulate cellular plasticity in a regenerative setting

  3. Findings suggest that p150 may link the DNA-bound Gfi1 repressor complex to histones enabling modifications required for transcriptional silencing.

  4. This recruitment is strictly dependent on p150CAF-1, the largest subunit of chromatin assembly factor 1 (CAF-1 (show RBBP4 Proteins)), and its ability to interact with HP1alpha (show CBX5 Proteins).

  5. during DNA replication, the interaction of HP1 (show CBX5 Proteins) with p150CAF-1 is essential to promote delivery of HP1 (show CBX5 Proteins) molecules to heterochromatic sites

  6. findings suggest that CAF-1 (show CNOT7 Proteins) is required for the maturation of heterochromatin during preimplantation development (show MTA2 Proteins) and that CAF-1 (show CNOT7 Proteins) is specifically required for heterochromatin organization in pluripotent embryonic cells

  7. Data show that human CAF-1 (p150) contains two PCNA (show PCNA Proteins) interaction peptides, and suggest that these peptides are part of the mechanism that enables CAF-1 (show CNOT7 Proteins) to function behind replication forks without interfering with other PCNA (show PCNA Proteins)-mediated processes.

CHAF1A Protein Profile

Protein Summary

Chromatin assembly factor I (CAF1) is a nuclear complex consisting of p50, p60 (CHAF1B\; MIM 601245), and p150 (CHAF1A) subunits that assembles histone octamers onto replicating DNA in vitro (Kaufman et al., 1995

Gene names and symbols associated with CHAF1A

  • chromatin assembly factor 1, subunit A (p150) (Chaf1a)
  • chromatin assembly factor 1, subunit A (p150) (CHAF1A)
  • chromatin assembly factor 1, subunit A (p150) (LOC100231993)
  • chromatin assembly factor 1, subunit A (p150) (chaf1a)
  • AL023013 protein
  • AL024058 protein
  • Cac1p protein
  • CAF-1 protein
  • CAF-1P150 protein
  • CAF-I-p150 protein
  • CAF-Ip150 protein
  • CAF1 protein
  • CAF1B protein
  • CAF1P150 protein
  • caip150 protein
  • CHAF1A protein
  • chaf1a-b protein
  • P150 protein
  • wu:fd14g10 protein
  • xp150 protein
  • zgc:153930 protein

Protein level used designations for CHAF1A

chromatin assembly factor 1, subunit A (p150) , chromatin assembly factor 1 subunit A-like , CAF-1 subunit A , CAF-I 150 kDa subunit , CAF-I p150 , chromatin assembly factor 1 subunit A , chromatin assembly factor I (150 kDa) , chromatin assembly factor I p150 subunit , hp150 , CAF-Ip150 , chromatin assembly factor-1p150 , Chromatin assembly factor I p150 subunit , CAF-I 150 kDa subunit B , CAF-I p150-B , CAF-Ip150-B , Chromatin assembly factor I p150 subunit B , chromatin assembly factor 1 subunit A-B

GENE ID SPECIES
363333 Rattus norvegicus
455603 Pan troglodytes
485038 Canis lupus familiaris
100231993 Taeniopygia guttata
100447657 Pongo abelii
100590477 Nomascus leucogenys
10036 Homo sapiens
27221 Mus musculus
504535 Bos taurus
770217 Gallus gallus
563212 Danio rerio
733264 Xenopus laevis
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