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Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities.
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binding of HNP1 (show DEFA1 Antibodies) to affected bacterial toxins caused their local unfolding, potentiated their thermal melting and precipitation, exposed new regions for proteolysis, and increased susceptibility to collisional quenchers.
DEFA1B encodes an antibacterial peptide that is bacteriocidal against S. aureus, E. coli, and P. aeruginosa.
Data show that H. pylori induces alpha-defensin (show DEF Antibodies) release from granulocytes, which may be important in local host response to H. pylori infection in gastroduodenal diseases.
Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram- negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.
neutrophil defensin 1