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anti-Chromobox Homolog 2 (CBX2) Antibodies

CBX2 encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Additionally we are shipping Chromobox Homolog 2 Proteins (6) and Chromobox Homolog 2 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CBX2 12416 P30658
CBX2 84733 Q14781
CBX2 303730  
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Top anti-Chromobox Homolog 2 Antibodies at antibodies-online.com

Showing 10 out of 67 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-CBX2 Antibody Titration: 0.2-1 ug/mlPositive Control... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of CBX2 Antibody (N-term) (ABIN653558) in MDA-MB... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of CBX2 Antibody (N-term) in MDA-MB231 cell line... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-CBX2 Antibody Titration: 0.2-1 ug/mlPositive Control... WB Suggested Anti-CBX2  Antibody Titration: 0.2-1 µg/mL  Positive Cont... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Mouse Rabbit Un-conjugated ELISA 50 μL Log in to see 2 to 3 Days
$220.50
Details
Human Rabbit Un-conjugated WB CBX2 Antibody (Center)  western blot analysis in mouse testis tissue l... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged CBX2 is approximately 3 ng/... 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

CBX2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) ,

Human , , , ,
, ,
Rat (Rattus) ,

Top referenced anti-Chromobox Homolog 2 Antibodies

  1. Human Polyclonal CBX2 Primary Antibody for WB - ABIN653558 : Katoh-Fukui, Tsuchiya, Shiroishi, Nakahara, Hashimoto, Noguchi, Higashinakagawa: Male-to-female sex reversal in M33 mutant mice. in Nature 1998 (PubMed)
    Show all 4 references for ABIN653558

  2. Human Polyclonal CBX2 Primary Antibody for EIA, WB - ABIN951074 : Gecz, Gaunt, Passage, Burton, Cudrey, Pearce, Fontes: Assignment of a Polycomb-like chromobox gene (CBX2) to human chromosome 17q25. in Genomics 1995 (PubMed)
    Show all 4 references for ABIN951074

  3. Chicken Polyclonal CBX2 Primary Antibody for WB - ABIN2784551 : García, Marcos-Gutiérrez, del Mar Lorente, Moreno, Vidal: RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1. in The EMBO journal 1999 (PubMed)

More Antibodies against Chromobox Homolog 2 Interaction Partners

Mouse (Murine) Chromobox Homolog 2 (CBX2) interaction partners

  1. We find that the N-terminus of Cbx2 is needed for its recruitment to mitotic chromosomes, whereas the C-terminus is required for its immobilization.

  2. Cbx2 targets PRC1 (show PRC1 Antibodies) to constitutive heterochromatin in mouse zygotes in a parent-of-origin-dependent manner.

  3. This study implicates Cbx2 in testis differentiation through regulating Sry (show SRY Antibodies) gene expression.

  4. Data show that Polycomb repressive complex 2 is necessary to maintain normal levels of OGT and for the correct cellular distribution of O-GlcNAc.

  5. Zfp277 in the transcriptional regulation of the Ink4a/Arf (show CDKN2A Antibodies) locus and the recruitment of PRC1 (show PRC1 Antibodies) to the Ink4a/Arf (show CDKN2A Antibodies) locus

  6. these results suggest that the binding specificity of Cbx2 protein for methylated histones is regulated by phosphorylation.

  7. murine geminin (show GMNN Antibodies) associates transiently with members of the Hox (show MSH2 Antibodies)-repressing polycomb complex, with the chromatin of Hox (show MSH2 Antibodies) regulatory DNA elements and with Hox (show MSH2 Antibodies) proteins

  8. Polycomb protein M33 controls critical expansion of B- and T-lymphocyte precursors

  9. The Polycomb M33 gene is an essential upstream regulator of Ad4BP/SF1 (show NR5A1 Antibodies).

  10. We conclude that this amino-acid stretch in M33 acts as the functional nuclear localization signal for this protein

Human Chromobox Homolog 2 (CBX2) interaction partners

  1. CBX2 role in the sex development cascade is to stimulate the male pathway and concurrently inhibit the female pathway.

  2. CBX2 upregulation and amplification significantly correlated with metastatic progression and lower overall survival in many cancer types, particularly those of the breast

  3. This study does not support CBX2 gene disruption as a common cause of gonadal gonadal disorders of sex development.

  4. Two distinct mechanisms are involved in CBX2-mediated gene silencing. The short CBX2-2 isoform would repress the transcription in a PRC1 (show PRC1 Antibodies)-independent fashion, whereas gene repression by the long CBX2-1 isoform is mediated by the PRC1 (show PRC1 Antibodies) protein complex.

  5. CDYL (show CDYL Antibodies) functions as a molecular bridge between PRC2 and the repressive chromatin mark H3K27me3, forming a positive feedback loop to facilitate the establishment and propagation of H3K27me3 modifications along the chromatin

  6. hPc2 (show ELAC2 Antibodies) serves as a SUMO E3 ligase (show PIAS1 Antibodies) for cystathionine beta-synthase (show CBS Antibodies), increasing the efficiency of sumoylation.

Chromobox Homolog 2 (CBX2) Antigen Profile

Protein Summary

This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene names and symbols associated with CBX2

  • chromobox homolog 2 (cbx2) antibody
  • chromobox homolog 2 (CBX2) antibody
  • chromobox homolog 2 (Drosophila Pc class) (cbx2) antibody
  • chromobox 2 (Cbx2) antibody
  • chromobox homolog 2 (Cbx2) antibody
  • cbx2 antibody
  • cdca6 antibody
  • m33 antibody
  • MOD2 antibody
  • pc antibody
  • pc1 antibody
  • SRXY5 antibody
  • wu:fd20e09 antibody
  • zgc:103563 antibody

Protein level used designations for CBX2

chromobox homolog 2 , modifier 3 protein , chromobox protein homolog 2-like , chromobox homolog 2 (Pc class homolog, Drosophila) , chromobox protein homolog 2 , M33 polycomb-like protein , hromobox homolog 2 , polycomb , Pc class homolog , cell division cycle associated 6 , modifier 3 , Polycomb homolog Pc1 , chromobox homolog 2 (Pc class homolog)

GENE ID SPECIES
100125497 Oryzias latipes
100410455 Callithrix jacchus
327291 Danio rerio
12416 Mus musculus
84733 Homo sapiens
398110 Xenopus laevis
426248 Gallus gallus
483349 Canis lupus familiaris
303730 Rattus norvegicus
Selected quality suppliers for anti-Chromobox Homolog 2 (CBX2) Antibodies
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