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CHD5 encodes a member of the chromodomain helicase DNA-binding protein family. Additionally we are shipping CHD5 Antibodies (28) and and many more products for this protein.
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Data show that chromodomain helicase DNA binding protein 5 (CHD5) acted as a functional tumor suppressor and was frequently silenced by promoter CpG methylation in renal cell carcinoma (RCC (show XRCC1 ELISA Kits)).
CHD5 (show WRB ELISA Kits) may act as a tumor suppressor gene in NSCLC.
Authors identified the CHD5 (show WRB ELISA Kits) as a direct target of miR (show MLXIP ELISA Kits)-454. CHD5 (show WRB ELISA Kits) was downregulated in HCC (show FAM126A ELISA Kits) tissues and cell lines and the expression level of CHD5 (show WRB ELISA Kits) was inversely correlated with the expression of miR (show MLXIP ELISA Kits)-454 in HCC (show FAM126A ELISA Kits) tissues.
Data show a mutual suppression regulation between chromodomain helicase DNA binding protein 5 (CHD5) and enhancer of zeste homolog 2 (EZH2 (show EZH2 ELISA Kits), which may provide new insights into their potential therapeutic significance for hepatocellular carcinoma (HCC (show FAM126A ELISA Kits)).
CHD5 (show WRB ELISA Kits) methylation of rectal cancer has a great effect in influencing its clinical and pathological features.
Study shows that CHD5 (show WRB ELISA Kits) is a Nucleosome remodeling and deacetylase complex-associated transcriptional repressor and identifies WEE1 (show WEE1 ELISA Kits) as one of the CHD5 (show WRB ELISA Kits)-regulated genes that may link CHD5 (show WRB ELISA Kits) to tumor suppression.
Low CHD5 (show WRB ELISA Kits) expression activates the DNA damage response and predicts poor outcome in patients undergoing adjuvant therapy for resected pancreatic cancer.
CHD5 (show WRB ELISA Kits) is a potential tumour suppressor gene epigenetically silenced in hepatocellular carcinoma.
The tumor suppressor chromodomain helicase DNA-binding protein 5 (CHD5) remodels nucleosomes by unwrapping.
repression of CHD5 (show WRB ELISA Kits) gene expression in human leukemia is mediated in part by DNA methylation (show HELLS ELISA Kits) of its promoter.
Chd5 represses murine endogenous retrovirus-L (MuERV-L/MERVL), an endogenous retrovirus-derived retrotransposon, by regulating H3K27me3 and H3.1/H3.2 function.
Chd5 (show WRB ELISA Kits) is a multi-faceted mediator of histone-to-protamine replacement and is important in the cascade of molecular events underlying this process of extensive chromatin remodelling.
Our data indicate that CHD5 (show WRB ELISA Kits) is required for normal spermiogenesis, especially for spermatid chromatin condensation.
Chd5 (show WRB ELISA Kits) expression is retained at high levels in differentiated neurons of the adult mouse.
These findings provide insights into the regulatory role of CHD5 (show WRB ELISA Kits) during neurogenesis and suggest how inactivation of this candidate tumor suppressor might contribute to neuroblastoma (show ARHGEF16 ELISA Kits).
Chd5 (show WRB ELISA Kits) binds the unmodified N terminus of H3 through its tandem plant homeodomains (PHDs).
CHD5 (show WRB ELISA Kits) regulates expression of neuronal genes, cell cycle genes and remodeling genes, and is linked to regulation of genes implicated in aging and Alzheimer's disease.
the association of between miR (show MLXIP ELISA Kits)-211-regulated CHD5 (show WRB ELISA Kits) expression and CHD5 (show WRB ELISA Kits) function in colorectal tumorigenesis
This gene encodes a member of the chromodomain helicase DNA-binding protein family. Members of this family are characterized by a chromodomain, a helicase ATP-binding domain and an additional functional domain. This gene encodes a neuron-specific protein that may function in chromatin remodeling and gene transcription. This gene is a potential tumor suppressor gene that may play a role in the development of neuroblastoma.
chromodomain helicase DNA binding protein 5
, Coronary heart disease, susceptibility to, 5
, chromodomain-helicase-DNA-binding protein 5-like
, ATP-dependent helicase CHD5
, chromodomain-helicase-DNA-binding protein 5