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Connective Tissue Growth Factor Proteins (CTGF)

The protein encoded by CTGF is a mitogen that is secreted by vascular endothelial cells. Additionally we are shipping CTGF Antibodies (226) and CTGF Kits (79) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CTGF 14219 P29268
CTGF 1490 P29279
CTGF 64032 Q9R1E9
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Top CTGF Proteins at antibodies-online.com

Showing 10 out of 71 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human GST tag Connective Tissue Growth Factor (CTGF) (AA 253-349), (partial) protein (GST tag) 50 μg Log in to see 9 to 11 Days
$217.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 4 to 6 Days
$412.50
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 2 to 3 Days
$619.50
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$313.50
Details
HOST_Escherichia coli (E. coli) Mouse GST tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Wild boar His tag 100 μg Log in to see 11 to 13 Days
$844.80
Details
HOST_Escherichia coli (E. coli) Sheep His tag 100 μg Log in to see 11 to 13 Days
$897.60
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$792.00
Details

CTGF Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
,
Human , , , , , ,
, , ,
Rat (Rattus) ,

Top referenced CTGF Proteins

  1. Human CTGF Protein expressed in Escherichia coli (E. coli) - ABIN1046858 : Bradham, Igarashi, Potter, Grotendorst: Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10. in The Journal of cell biology 1991 (PubMed)
    Show all 2 references for ABIN1046858

More Proteins for Connective Tissue Growth Factor (CTGF) Interaction Partners

Rhesus Monkey Connective Tissue Growth Factor (CTGF) interaction partners

  1. These data suggest that CTGF levels are increased in multiple organs after radiation exposure and that inflammatory cell infiltration may contribute to the elevated levels of CTGF in multiple organs.

Zebrafish Connective Tissue Growth Factor (CTGF) interaction partners

  1. CTGF/CCN2 plays an important role in notochord development and is required for general embryonic development

Mouse (Murine) Connective Tissue Growth Factor (CTGF) interaction partners

  1. Under physiological conditions, CCN2 may be regulating the levels of free amino acids in the extracellular matrix of cartilage.

  2. These data indicate that LPA increases CCN2 expression through the activation of PKC and PKA. Thus, the regulatory functions of the PKC and PKA pathways are implicated in the LPA-induced increase in CCN2 expression

  3. CTGF inhibition may benefit patients with dilated cardiomyopathy.

  4. These results suggest that TGF-beta1 (show TGFB1 Proteins) and CTGF may be involved in the process of denervated skeletal muscle fibrosis.

  5. RhoA determines lineage fate of mesenchymal stem cells by modulating CTGF-VEGF complex in extracellular matrix.

  6. CTGF knockout does not affect cardiac hypertrophy and fibrosis formation upon chronic pressure overload.

  7. In cultured neonatal cardiac fibroblasts, p63RhoGEF regulated the angiotensin II (Ang II)-dependent RhoA (show RHOA Proteins) activation, the activation of the serum response factor, and the expression and secretion of CTGF.

  8. these findings reveal a key role of the SRF/CTGF/miR (show MLXIP Proteins)-133a axis in the regulation of cardiac fibrosis

  9. Descriptive Statement Elimination of TGF-betaIIR is not sufficient to completely prevent liver fibrosis. TGF-beta (show TGFB1 Proteins)-independent mechanism of type I collagen production and suggest connective tissue growth factor as its potent mediator.

  10. CCN2 up regulation by tumor stromal cells is responsible for the melanoma metastasis.

Human Connective Tissue Growth Factor (CTGF) interaction partners

  1. Findings suggest that GDF8 (show MSTN Proteins) and CTGF may play critical roles in the regulation of proliferative events in human granulosa cells.

  2. Studies indicate that the CYR61 (show CYR61 Proteins) CTGF NOV (show NOV Proteins) matricellular proteins (CCN family of proteins) comprises the members CCN1 (show CCNA2 Proteins), CCN2, CCN3 (show NOV Proteins), CCN4 (show WISP1 Proteins), CCN5 (show WISP2 Proteins) and CCN6 (show WISP3 Proteins) and have been identified in various types of cancer.

  3. renoprotective therapeutic agents can specifically abolish CCN2 expression in diabetic nephropathy; CCN2 plays a pivotal role in disease progression [review]

  4. CTGF was able to induce tumor cell epithelial-mesenchymal transition (EMT (show ITK Proteins)), and promote stroma deposition of collagen I fibers to stimulate tumor growth and metastasis.

  5. The role of CTGF in the gastric cancer peritoneal metastasis:CTGF blocks integrin alpha3beta1-dependent adhesion of cancer cells.

  6. TGF-beta (show TGFB1 Proteins) and CCN2 play an important role in IUA formation.

  7. Data describe a novel SMAD-binding element located in the 5'UTR region of the murine CTGF gene that regulates the expression of CTGF induced by TGF-b in C2C12 myoblast cell line, which involves SMAD3 and SP1/SP3 transcription factors.

  8. The expression of CTGF is an independent factor associated with shorter overall survival in hepatocellular carcinoma.

  9. Results showed that CTGF were expressed in human granulosa cells and up-regulated by TGF-beta1 through the activation of Smad and ERK1/2 signaling pathway.

  10. Report opposing effects of CCN2 and CCN5 (show WISP2 Proteins) on fibroblast proliferation and transdifferentiation induced by TGF-beta (show TGFB1 Proteins).

Pig (Porcine) Connective Tissue Growth Factor (CTGF) interaction partners

  1. CCN2 was transiently expressed at the leading keratinocyte edge in wound healing.

  2. Atrial fibrillation patients and animals exhibited a significantly increased expression of connective tissue growth factor (CTGF). Angiotension II-induced CTGF expression might be involved in atrial substrate remodeling.

  3. CTGF in trabecular meshwork is modulated by physiological agonists and by increased ocular pressure and mechanical stretch. Regulation of CTGF within outflow pathway may play role in homeostasis of intraocular pressure.

  4. CTGF level was not altered in model of obliterative bronchiolitis.

Cow (Bovine) Connective Tissue Growth Factor (CTGF) interaction partners

  1. The results indicate that CTGF suppresses the synthesis of biglycan (show BGN Proteins) but newly induced that of decorin (show DCN Proteins) in the cells when the cell density is low.

  2. Actin cytoskeleton-dependent regulation of CTGF transcription and mRNA stability

Rabbit Connective Tissue Growth Factor (CTGF) interaction partners

  1. A significant increase in TGF-beta1 (show TGFB1 Proteins) and CTGF was found at 6 weeks in the subsynovial connective tissue in a rabbit model of carpal tunnel syndrome.

  2. Stretch is an important primary trigger for CTGF-induction in the overloaded heart.

  3. Connective tissue growth factor is expressed in the naive cornea, lens, iris, and retina, and is expressed immediately after epithelial injury. Loss of CTGF impairs efficient re-epithelialization of corneal wounds.

  4. TGF-beta1 (show TGFB1 Proteins) can inhibit the growth of urethra epithelium cells and induce the expression of CTGF.

  5. Overexpression of CTGF in the blebs after trabeculectomy demonstrates that CTGF may play an important role in the process of wound healing.

Xenopus laevis Connective Tissue Growth Factor (CTGF) interaction partners

  1. Recombinant CTGF added to embryonic mouse neural precursor cell culture increased the number of Sox-2 (show SOX2 Proteins)-, GFAP (show GFAP Proteins)-and GFAP (show GFAP Proteins)/Nestin (show NES Proteins)-positive cells, activated p44 (show GTF2H2 Proteins)/42 signaling, and upregulated fibronectin (show FN1 Proteins). In human glioma cells, it induced GFAP (show GFAP Proteins) and nestin (show NES Proteins).

  2. Data show that connective-tissue growth factor regulates signalling through the Wnt (show WNT2 Proteins) pathway, in accord with its ability to bind to the Wnt (show WNT2 Proteins) co-receptor LDL receptor (show LDLR Proteins)-related protein 6 (LRP6 (show LRP6 Proteins)).

CTGF Protein Profile

Protein Summary

The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis.

Gene names and symbols associated with CTGF

  • WNT1 inducible signaling pathway protein 2 (wisp2)
  • connective tissue growth factor (ctgf)
  • connective tissue growth factor (CTGF)
  • connective tissue growth factor b (ctgfb)
  • Connective tissue growth factor (ctgf)
  • connective tissue growth factor (Ctgf)
  • connective tissue growth factor (CCN2)
  • connective tissue growth factor a (ctgfa)
  • connective tissue growth factor-like (LOC476202)
  • CCN2 protein
  • ccn5 protein
  • ct58 protein
  • CTGF protein
  • ctgf-l protein
  • CTGRP protein
  • fisp-12 protein
  • Fisp12 protein
  • HCS24 protein
  • hm:zeh1559 protein
  • IGFBP8 protein
  • NOV2 protein
  • si:ch211-173b8.2 protein
  • si:dkey-266k12.4 protein
  • wu:fl25c03 protein
  • XCTGF protein
  • zeh1559 protein
  • zgc:136644 protein

Protein level used designations for CTGF

WNT1 inducible signaling pathway protein 2 , connective tissue growth factor , zCTGF-c19 , Connective tissue growth factor , connective tissue growth factor-like , CCN family member 2 , Connective tissue growth factor precursor (CTGF) (FISP-12 protein) (Hypertrophic chondrocyte-specific protein 24) , fibroblast inducible secreated protein , fibroblast inducible secreted protein , hypertrophic chondrocyte-specific gene product 24 , hypertrophic chondrocyte-specific protein 24 , IBP-8 , IGF-binding protein 8 , IGFBP-8 , insulin-like growth factor-binding protein 8 , connective tissue growth-related protein , connective tissue growth factor XCTGF , zCTGF-c20

GENE ID SPECIES
496678 Xenopus (Silurana) tropicalis
548598 Xenopus (Silurana) tropicalis
714520 Macaca mulatta
100124530 Danio rerio
100137400 Papio anubis
100194970 Salmo salar
100437145 Pongo abelii
100604830 Nomascus leucogenys
14219 Mus musculus
1490 Homo sapiens
64032 Rattus norvegicus
374135 Gallus gallus
100152141 Sus scrofa
281103 Bos taurus
100303607 Ovis aries
100008638 Oryctolagus cuniculus
100726380 Cavia porcellus
398003 Xenopus laevis
463003 Pan troglodytes
321449 Danio rerio
476202 Canis lupus familiaris
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