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Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. Additionally we are shipping CPNE1 Antibodies (40) and many more products for this protein.
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Human CPNE1 Protein expressed in Baculovirus infected Insect Cells - ABIN2006124
Tomsig, Snyder, Creutz: Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif. in The Journal of biological chemistry 2003
Copine I regulates tumour necrosis factor-alpha (show TNF Proteins) receptor signaling pathways.
Copine1 is upregulated in plasma membranes of TM cells in individuals with primary open-angle glaucoma.
CPNE1 shares a promoter and 5'UTR exons with RBM12 (show RBM12 Proteins). This genomic structure is conserved among multiple species.
Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene encodes a calcium-dependent protein that also contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, the encoded protein does not contain a predicted signal sequence or transmembrane domains. This protein has a broad tissue distribution and it may function in membrane trafficking. This gene and the gene for RNA binding motif protein 12 overlap at map location 20q11.21. Alternate splicing results in multiple transcript variants encoding different proteins.
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