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Crystallin, gamma C Proteins (CRYGC)

Crystallins are separated into two classes taxon-specific, or enzyme, and ubiquitous. Additionally we are shipping CRYGC Antibodies (35) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CRYGC 1420 P07315
CRYGC 24277 P02529
CRYGC 12966 Q61597
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Top CRYGC Proteins at antibodies-online.com

Showing 9 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,401.67
Details
Yeast Dog His tag   1 mg Log in to see 56 to 66 Days
$2,401.67
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,401.67
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CRYGC Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

Mouse (Murine)

Top referenced CRYGC Proteins

  1. Human CRYGC Protein expressed in Escherichia coli (E. coli) - ABIN1098275 : Ren, Li, Shastry, Padma, Ayyagari, Scott, Parks, Kaiser-Kupfer, Hejtmancik: A 5-base insertion in the gammaC-crystallin gene is associated with autosomal dominant variable zonular pulverulent cataract. in Human genetics 2000 (PubMed)
    Show all 2 references for ABIN1098275

More Proteins for Crystallin, gamma C (CRYGC) Interaction Partners

Human Crystallin, gamma C (CRYGC) interaction partners

  1. the G129C mutation in gammaC-crystallin, which is associated with autosomal dominant congenital nuclear cataract, perturbed the unfolding process by promoting the accumulation of two distinct aggregation-prone intermediates under mild denaturing conditions.

  2. Exome sequencing in developmental eye disease leads to identification of causal variants in GJA8 (show GJA8 Proteins), CRYGC, PAX6 (show PAX6 Proteins) and CYP1B1 (show CYP1B1 Proteins).

  3. We confirm that congenital cataract is associated with a CRYGC gene mutation.

  4. identified a CRYAA (show CRYAA Proteins) mutation in family A and a CRYGC mutation in family B with congenital cataract

  5. A nonsense mutation c.471G>A in CRYGC is associated with autosomal dominant congenital nuclear cataracts and microcornea in a Chinese pedigree.

  6. Molecular modeling and spectroscopic studies indicated that the mutation impaired the tertiary structure of gamma C crystallin by modifying the H-bonding network in the C-terminal domain.

  7. Two novel nonsynonymous variations and four reported variations in CRYAB (show CRYAB Proteins), CRYGC, CRYGD (show CRYGD Proteins), and GJA8 (show GJA8 Proteins), were observed.

  8. In gammaD-crystallin, methylation is exclusively at Cys (show DNAJC5 Proteins) 110, whereas in gammaC- and gammaB-crystallins, the principal methylation site is Cys (show DNAJC5 Proteins) 22 with minor methylation at Cys (show DNAJC5 Proteins) 79

  9. the loss of interactions of T5P mutant of the gammaC-crystallin with other crystallins may play a larger role than the protection afforded by chaperone-like activity in Coppock-like cataract.

  10. This is the first case of phenotypic heterogeneity in the primary congenital cataract specifically associated with the R168W mutation in the CRYGC gene.

Cow (Bovine) Crystallin, gamma C (CRYGC) interaction partners

Mouse (Murine) Crystallin, gamma C (CRYGC) interaction partners

  1. a 1-bp deletion in gammaC-crystallin leads to cataract.

  2. presence of measurable interactions between MIP26 and all crystallins, with the extent of interactions decreasing from alphaA- and alphaB-crystallin (show CRYAB Proteins) to betaB2- and gammaC-crystallin.

CRYGC Protein Profile

Protein Summary

Crystallins are separated into two classes taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families\; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.

Gene names and symbols associated with Crystallin, gamma C Proteins (CRYGC)

  • crystallin, gamma C (crygc)
  • crystallin, gamma C (CRYGC)
  • crystallin, gamma C (LOC100354942)
  • crystallin, gamma C (LOC100358871)
  • crystallin, gamma C (Crygc)
  • CCL protein
  • Cryg protein
  • Cryg-5 protein
  • Cryg3 protein
  • CTRCT2 protein
  • Len protein
  • MGC84008 protein

Protein level used designations for Crystallin, gamma C Proteins (CRYGC)

crystallin, gamma C , gamma-crystallin C , crystallin, gamma-3 , gamma-C-crystallin , gamma-crystallin 2-1 , gamma-crystallin 3 , gamma-crystallin IIIA , gammaC-crystallin , crystallin, gamma polypeptide 3

GENE ID SPECIES
444574 Xenopus laevis
737363 Pan troglodytes
100354942 Oryctolagus cuniculus
100358871 Oryctolagus cuniculus
1420 Homo sapiens
100126770 Canis lupus familiaris
281722 Bos taurus
24277 Rattus norvegicus
12966 Mus musculus
100337641 Cavia porcellus
709553 Macaca mulatta
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