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CTBP2 produces alternative transcripts encoding two distinct proteins. Additionally we are shipping CTBP2 Proteins (9) and CTBP2 Kits (6) and many more products for this protein.
Showing 10 out of 87 products:
Rat (Rattus) Polyclonal CTBP2 Primary Antibody for IHC - ABIN1742397
Regus-Leidig, tom Dieck, Brandstätter: Absence of functional active zone protein Bassoon affects assembly and transport of ribbon precursors during early steps of photoreceptor synaptogenesis. in European journal of cell biology 2010
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Dog (Canine) Monoclonal CTBP2 Primary Antibody for IF, WB - ABIN968723
Hendrickson, Troilo, Djajadi, Possin, Springer: Expression of synaptic and phototransduction markers during photoreceptor development in the marmoset monkey Callithrix jacchus. in The Journal of comparative neurology 2008
Show all 6 Pubmed References
Human Polyclonal CTBP2 Primary Antibody for ICC, IHC - ABIN1742398
Dominik Fischer, Zobor, Keliris, Shao, Seeliger, Haverkamp, Jägle, Logothetis, Smirnakis: Detailed functional and structural characterization of a macular lesion in a rhesus macaque. in Documenta ophthalmologica. Advances in ophthalmology 2016
Show all 5 Pubmed References
Human Polyclonal CTBP2 Primary Antibody for IHC, WB - ABIN1742396
Zabouri, Haverkamp: Calcium channel-dependent molecular maturation of photoreceptor synapses. in PLoS ONE 2013
Show all 3 Pubmed References
Human Polyclonal CTBP2 Primary Antibody for ELISA, WB - ABIN560519
Debiais-Delpech, Godet, Pedretti, Bernard, Irani, Cathelineau, Cussenot, Fromont: Expression patterns of candidate susceptibility genes HNF1? and CtBP2 in prostate cancer: association with tumor progression. in Urologic oncology 2014
CtBP2 ameliorated palmitic acid-induced insulin (show INS Antibodies) resistance via ROS (show ROS1 Antibodies)-dependent JNK (show MAPK8 Antibodies) pathway.
CtBP2 is a druggable transforming oncoprotein critical for the evolution of neoplasia driven by Apc (show APC Antibodies) mutation.
CtBP2 may be a potential target to suppress tumorigenesis in neuroblastoma (show ARHGEF16 Antibodies)
This Gene-based tests suggest evidence of association with related genes, ZEB2 (show ZEB2 Antibodies), RND3 (show RND3 Antibodies), MCTP1, CTBP2, and beta EEG
Our results indicated that CCNH (show CCNH Antibodies)/CDK7 (show CDK7 Antibodies)-CtBP2 axis may augment ESCC cell migration, and targeting the interaction of both may provide a novel therapeutic target of esophageal squamous cell carcinoma .
Releasing the key adipogenic regulator C/EBPalpha (show CEBPA Antibodies) from CtBP2 binding.
Enhanced CtBP2expression promoted HCC (show FAM126A Antibodies) xenograft growth and induced EMT (show ITK Antibodies).
results show how CtBP2 contributes to prostate cancer progression by modulating AR and oncogenic signaling
High CTBP2 expression is associated with prostate cancer.
Overexpression of CtBP2 is associated with breast carcinoma.
studies revealed a new epigenetic pathway in the control of IL-2 (show IL2 Antibodies) production in systemic lupus erythematosus whereby low levels of miR (show MLXIP Antibodies)-200a-3p accumulate the binding of the ZEB1 (show ZEB1 Antibodies)-CtBP2 complex to the IL-2 (show IL2 Antibodies) promoter and suppress IL-2 (show IL2 Antibodies) production
Our results show that RIBEYE is essential for synaptic ribbons as such, and may organize presynaptic nano-domains that position release-ready synaptic vesicles adjacent to Ca(2 (show CA2 Antibodies)+) channels
Ctbp2 preoccupies regions in active genes with the NuRD complex in undifferentiated ESCs (show NR2E3 Antibodies) that are directed toward H3K27me3 by PRC2 to induce stable silencing, which is pivotal for natural lineage commitment.
Phosphorylation of KLF3 (show KLF3 Antibodies) and CtBP2 by HIPK2 (show HIPK2 Antibodies) strengthens the interaction between these two factors and increases transcriptional repression by KLF3 (show KLF3 Antibodies).
propose that Zscan4 (show ZSCAN4 Antibodies) may regulate gene transcription in mouse ES cells through interaction with LSD1 (show KDM1A Antibodies) and CtBP2
RIBEYE(B) interacts with ArfGAP3 (show ARFGAP3 Antibodies) in vivo and in vitro.
CTBP2 is indispensable to create a chromatin environment conducive for RAR (show RARA Antibodies)/RXR-mediated transcription by recruiting the histone acetyltransferase p300 (show EP300 Antibodies).
Study demonstrates differential regional and subcellular expression patterns for the two CtBP family members in brain and reveals a previously unknown synaptic localization for CtBP2 in particular brain regions.
Ctbp2 has a role in maintaining a balance in decisions to self-renewal and differentiate in embryonic stem cells and mesodermal progenitors
Mice harboring various combinations of Ctbp1 (show CTBP1 Antibodies) and Ctbp2 mutant alleles exhibit dosage-sensitive defects in a wide range of developmental processes
In photoreceptor cells, RIBEYE and RIM2 (show RIMS2 Antibodies) are expressed along the synaptic ribbon.
Tcf-3 (show TCF3 Antibodies) functions as a transcriptional regulator in the canonical Wnt (show WNT2 Antibodies) signaling cascade and can repress or activate downstream target genes. The tcf-3 (show TCF3 Antibodies) promoter was analyzed during early development of Xenopus.
Together, these results demonstrate that signaling through Tcf (show HNF4A Antibodies) and Vent binding sites regulates transcription of geminin (show GMNN Antibodies) in prospective neurectoderm during gastrulation
This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3\; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10.
C-terminal binding protein 2
, C-terminal-binding protein 2-like
, C-terminal-binding protein 2
, gene trap ROSA b-geo 6
, ribeye a
, C-terminal-binding protein B
, TCF-3 corepressor CtBP
, Tcf-3 co-repressor CtBP