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Cyclin D-Type Binding-Protein 1 Proteins (CCNDBP1)

CCNDBP1 was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. Additionally we are shipping Cyclin D-Type Binding-Protein 1 Antibodies (81) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CCNDBP1 23582 O95273
CCNDBP1 17151 Q3TVC7
CCNDBP1 362201 Q5BK06
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Top Cyclin D-Type Binding-Protein 1 Proteins at antibodies-online.com

Showing 8 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$2,893.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,964.50
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,973.67
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$2,979.17
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 9 to 11 Days
$229.85
Details

CCNDBP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Cyclin D-Type Binding-Protein 1 (CCNDBP1) Interaction Partners

Human Cyclin D-Type Binding-Protein 1 (CCNDBP1) interaction partners

  1. Data suggest MAID/CCNDBP1 inhibits cell migration induced by TGFB1 (show TGFB1 Proteins) (transforming growth factor-beta1) but not by BMP4 (bone morphogenetic protein-4 (show BMP4 Proteins)); MAID does not alter cell proliferation, epithelial-mesenchymal transition, or TGFB3 (show TGFB3 Proteins)-induced apoptosis.

  2. GCIP underexpression is associated with Osteosarcoma.

  3. Data indicate that grap2 (show GRAP2 Proteins) and cyclin D1 (show CCND1 Proteins) interacting protein (GCIP) and inhibitor of of DNA binding/differentiation 1 (Id1 (show ID1 Proteins)) are inversely expressed in non-small cell lung cancer (NSCLC) cell lines and specimens.

  4. The first structure of a free-standing human dominant-negative helix-loop-helix protein (show ID1 Proteins) (DIP1) was reported. DIP1 adopts a V-shaped conformation, with N-terminal and C-terminal five-helix bundles connected by the HLH region.

  5. It is proposed for the first time that Rad may promote carcinogenesis at least in part by inhibiting GCIP-mediated tumor suppression.

  6. In transgenic mice, GCIP functions as a transcriptional suppressor, regulates cyclin D1 (show CCND1 Proteins) expression, inhibits cell growth and colony formation in human HepG2 cells, suggesting GCIP plays a significant role in tumor initiation and development.

  7. CT847 interacts with mammalian Grap2 cyclin D-interacting protein

  8. P0 overexpression may cause tumorigenesis in breast and liver tissues at least in part by inhibiting GCIP-mediated tumor suppression.

  9. Data suggest that HHM/Maid regulates a subset of TGF-beta (show TGFB1 Proteins) target genes including the Olig1 (show OLIG1 Proteins)-Smad (show SMAD1 Proteins) synexpression group.

  10. decreased expression of GCIP in vivo is present in human breast carcinoma.

Mouse (Murine) Cyclin D-Type Binding-Protein 1 (CCNDBP1) interaction partners

  1. Data suggest Maid/Ccndbp1 inhibits cell migration induced by TGFB1 (show TGFB1 Proteins) (transforming growth factor-beta1) but not by BMP4 (bone morphogenetic protein-4 (show BMP4 Proteins)); Maid does not alter cell proliferation, epithelial-mesenchymal transition, or TGFB3 (show TGFB3 Proteins)-induced apoptosis.

  2. These results indicate that Maid is involved in G1/S-phase progression of hepatocytes, which in older animals is associated with the development of liver tumors.

Cyclin D-Type Binding-Protein 1 (CCNDBP1) Protein Profile

Protein Summary

This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene.

Gene names and symbols associated with CCNDBP1

  • cyclin D-type binding-protein 1 (CCNDBP1)
  • cyclin D-type binding-protein 1 (ccndbp1)
  • cyclin D-type binding-protein 1 (Ccndbp1)
  • AU022347 protein
  • CCNDBP1 protein
  • DIP1 protein
  • GCIP protein
  • HHM protein
  • Maid protein
  • SECC-8 protein
  • SSEC-8 protein

Protein level used designations for CCNDBP1

cyclin D-type binding-protein 1 , D-type cyclin-interacting protein 1 , cyclin-D1-binding protein 1 , grap2 and cyclin-D-interacting protein , human homolog of Maid , maternal Id-like protein , maternal inhibition of differentiation , stage specific embryonic cDNA-8 protein

GENE ID SPECIES
419217 Gallus gallus
453373 Pan troglodytes
100101758 Xenopus (Silurana) tropicalis
607896 Canis lupus familiaris
23582 Homo sapiens
17151 Mus musculus
362201 Rattus norvegicus
617512 Bos taurus
100171439 Pongo abelii
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