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Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 Proteins (CYP1B1)

CYP1B1 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP1B1 Antibodies (81) and CYP1B1 Kits (23) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CYP1B1 1545 Q16678
CYP1B1 13078 Q64429
Rat CYP1B1 CYP1B1 25426 Q64678
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Top CYP1B1 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 11 to 13 Days
$880.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$1,046.42
Details

CYP1B1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) Interaction Partners

Human Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) interaction partners

  1. CYP1B1 genetic polymorphisms may influence outcome of taxane therapy in Roma and Hungarian populations.

  2. Results show that CYP1B1 may promote renal cell carcinoma (show MOK Proteins) development by inducing CDC20 (show CDC20 Proteins) expression and inhibiting apoptosis through the down-regulation of DAPK1 (show DAPK1 Proteins).

  3. The rate of CYP1B1 mutations in Lebanese patients with primary congenital glaucoma (PCG) is lower than that reported in other Arab and Middle Eastern populations and suggests other genes are responsible.

  4. This dysmorphic girl is Saudi Arabian and has CYP1B1-negative primary congenital glaucoma suggests that her glaucoma phenotype is related to her de novo copy number variation.

  5. data suggests that CYP1B1 promotes cell proliferation and metastasis by inducing EMT (show ITK Proteins) and Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling via Sp1 (show PSG1 Proteins) induction

  6. drugs acting as D2-dopamine receptor (show DRD2 Proteins) antagonists can modify several hormone systems that regulate the expression of CYP1A1 (show CYP1A1 Proteins), CYP1A2 (show CYP1A2 Proteins) and CYP1B1, and may affect the toxicity and carcinogenicity outcome of numerous toxicants and pre-carcinogenic substances

  7. Results suggest that CYP1B1 up-regulation mediated by low miR (show MLXIP Proteins)-200c is one of the mechanisms underlying resistance of RCC (show XRCC1 Proteins) cells to docetaxel.

  8. data show that in the leukocytes with mutant alleles treatment with 17beta-E2 up-regulates CYP1A1 (show CYP1A1 Proteins) and CYP1B1 and down-regulates COMT (show COMT Proteins) mRNA levels, resulting in major increments in 4-OHE2 levels

  9. Data show that the AS-PCR/RFLP assay has successfully constructed the haplotypes of the cytochrome P-450 CYP1B1 (CYP1B1) gene.

  10. Leu432Val Polymorphism of CYP1B1 is Not Associated with Squamous Cell Carcinoma of Esophagus.

Mouse (Murine) Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) interaction partners

  1. hypertension, and associated pathogenesis in ApoE (show APOE Proteins)(-/-)/Cyp1b1(+/+) mice on an atherogenic diet are most likely dependent on CYP1B1-generated oxidative stress and increased plasma lipid levels independent of blood pressure and absorption of lipids.

  2. Follicle stimulating hormone functions via p38 MAPK (show MAPK14 Proteins)-induced dephosphorylation at Ser (show SIGLEC1 Proteins)(727) of STAT1 (show STAT1 Proteins) to downregulate Cyp1b1 expression and maintain the estradiol levels in mouse dominant follicles.

  3. Cyp1b1 contributes to angiotensin II induced hypertension and its pathogenesis in male mice.

  4. Suggest that Cyp1b1 plays a critical role in female mice in protecting against renal dysfunction and end-organ damage associated with ANG II (show AGT Proteins)-induced hypertension.

  5. Data indicaate that adduct formation in cytochrome P450 Cyp1b1 knockout mice was significantly reduced compared to wild-type mice receiving dibenzo[def,p]chrysene (DBC).

  6. Cyp1b1 deletion substantially alters the expression of genes associated with fatty acid homeostasis

  7. Data indicate that hepatic stearoyl-CoA desaturase 1 (SCD1) expression was decreased in cytochrome P450 1B1 (CYP1B1)-null mice.

  8. Using inhibitors of p38 (show CRK Proteins) and MSKs, as well as mouse embryonic cells derived from p38alpha (show MAPK14 Proteins)-deficient and MSK1 (show RPS6KA5 Proteins)/2 double knockout mice, we show here that TNF-alpha (show TNF Proteins) potentiates CYP1B1 upregulation via the p38 (show CRK Proteins)/MSK1 (show RPS6KA5 Proteins) kinase cascade

  9. a direct role for mitochondrial CYP1B1 in PAH-mediated oxidative and chemical damage to mitochondria.

  10. Cyp1B1 expression in vascular cells plays an important role in the regulation of the cellular reductive state, thrombospondin (TSP)2 (show THBS2 Proteins) expression, and NF-kappaB (show NFKB1 Proteins) activation.

Zebrafish Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) interaction partners

  1. CYP1B1 knockdown studies show CYP1B1 is not a significant factor in causing synergistic toxicity of PAHs, nor, in contrast to CYP1A, in providing protection

CYP1B1 Protein Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma\; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.

Gene names and symbols associated with CYP1B1

  • cytochrome P450 1B1 (CYP1B1)
  • cytochrome P450, family 1, subfamily B, polypeptide 1 (CYP1B1)
  • cytochrome P450 1B1-like (LOC100719054)
  • cytochrome P450, family 1, subfamily b, polypeptide 1 (Cyp1b1)
  • cytochrome P450, family 1, subfamily B, polypeptide 1 (cyp1b1)
  • CP1B protein
  • CYP1B protein
  • CYP1B1 protein
  • CYPIB1 protein
  • GLC3A protein
  • P4501b1 protein
  • zgc:136223 protein

Protein level used designations for CYP1B1

cytochrome P450 1B1 , cytochrome P450, family 1, subfamily B, polypeptide 1 , aryl hydrocarbon hydroxylase , cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile) , flavoprotein-linked monooxygenase , microsomal monooxygenase , xenobiotic monooxygenase , CYPIB1 , benz[a]anthracene inducible , cytochrome P450, 1b1, benz[a]anthracene inducible , cytochrome P450CMEF , cytochrome P450EF , P450RAP , cytochrome P450, subfamily 1B, polypeptide 1 , cytochrome P450RAP , cytochrome P4501B

GENE ID SPECIES
100079784 Ornithorhynchus anatinus
100172192 Pongo abelii
459163 Pan troglodytes
100719054 Cavia porcellus
1545 Homo sapiens
428832 Gallus gallus
511470 Bos taurus
13078 Mus musculus
25426 Rattus norvegicus
100150054 Danio rerio
483038 Canis lupus familiaris
421466 Gallus gallus
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