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Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 Proteins (CYP2A6)

CYP2A6, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP2A6 Antibodies (85) and CYP2A6 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CYP2A6 1548 P11509
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Top CYP2A6 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CYP2A6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6) Interaction Partners

Pig (Porcine) Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6) interaction partners

  1. Polymorphisms within the CYP2A6 gene are not a significant cause of high skatole levels.

Human Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6) interaction partners

  1. It was concluded that, although decreased CYP2A6 AS tended to reduce the risk of bladder cancer in Japanese smokers, no significant association was recognized in this population.

  2. Reduced metabolism CYP2A6 genotypes are associated with both risk and protective effects in young smokers.

  3. Slow nicotine metabolism mediated by CYP2A6 increases risk for tobacco dependence throughout adolescence.

  4. carcinogen exposure and thereby lower risk of lung cancer. Despite the association between nicotine metabolism (CYP2A6 activity phenotype and diplotypes) and smoking intensity

  5. lower lung cancer risk observed in CYP2A6 poor metabolizers is partially explained by the strong influence of CYP2A6 genetic polymorphisms on nicotine uptake and metabolism

  6. phenotypic association studies in population in Nigeria: Data suggest polymorphisms in CYP2A6 exist in the population studied; distribution of CYP2A6 activity is trimodal; influence of age/sex on activity are not significant in this biomarker study.

  7. Report isolation of CYP2A6 inhibitors from Vernonia cinerea.

  8. Optical Isomers of Atorvastatin, Rosuvastatin and Fluvastatin Enantiospecifically Activate Pregnane X Receptor PXR (show NR1I2 Proteins) and Induce CYP2A6, CYP2B6 (show CYP2B6 Proteins) and CYP3A4 (show CYP3A4 Proteins) in Human Hepatocytes.

  9. CYP2A6 genetic polymorphisms may play important roles in the development of SQCC in Japanese smokers.

  10. The detected CYP2A6 variants explain a strikingly large fraction of variance (up to 31%) in nicotine metabolite ratio (NMR) in these study samples.

CYP2A6 Protein Profile

Protein Summary

This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3\; however, it has been renamed CYP2A6.

Gene names and symbols associated with CYP2A6

  • cytochrome P450 2A19 (CYP2A19)
  • cytochrome P450, family 2, subfamily A, polypeptide 6 (CYP2A6)
  • CPA6 protein
  • CYP2A protein
  • CYP2A3 protein
  • CYP2A6 protein
  • CYPIIA6 protein
  • P450C2A protein
  • P450PB protein

Protein level used designations for CYP2A6

coumarin 7-hydroxylase , cytochrome p450 2A6 , 1,4-cineole 2-exo-monooxygenase , cytochrome P450 2A6 , cytochrome P450 IIA3 , cytochrome P450(I) , cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 6 , flavoprotein-linked monooxygenase , xenobiotic monooxygenase

GENE ID SPECIES
403149 Sus scrofa
1548 Homo sapiens
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