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Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 Proteins (CYP2R1)

CYP2R1 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 Antibodies (68) and Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CYP2R1 120227 Q6VVX0
CYP2R1 244209 Q6VVW9
Rat CYP2R1 CYP2R1 361631  
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Top Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CYP2R1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1) Interaction Partners

Human Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1) interaction partners

  1. Vitamin D related (VDR rs2228570 and CYP2R1 rs10741657) and IL28B rs12979860 genes polymorphisms accurately assure sustained viral response in naive CHC G4 patients treated with low cost standard therapy.

  2. The aim of this study was to investigate the association of three polymorphisms in the GC gene (rs7041 and rs4588) and CYP2R1 gene (rs10741657) on 25-(OH) VD serum concentration among Jordanians.

  3. rs11023374 in CYP2R1 was significantly associated with serum 25(OH)D3.

  4. The VDR (show CYP27B1 Proteins) and CYP2R1 variants may be involved in genetic interactions in the pathogenesis of persistent allergic rhinitis.

  5. Significant associations were found between the GC (rs2282679 and rs7041), CYP2R1 (rs10741657) single nucleotide polymorphisms and the active form of Vitamin D, 25(OH)D.

  6. Polymorphisms in CYP2R1-rs10766197 and DHCR7 (show DHCR7 Proteins)/NADSYN1 (show NADSYN1 Proteins)-rs12785878 are associated with vitamin D deficiency in Uygur and Kazak ethnic populations

  7. The 25-hydroxylases CYP2R1 and CYP27A1 (show CYP27A1 Proteins) catalyze vitamin D to its circulating form 25-hydroxyvitamin D.

  8. A significant association was found between decreased ASD (show ARSD Proteins) risk and child CYP2R1 AA-genotype.

  9. Found a significant upregulation of the CYP2R1 gene in human brain pericytes challenged with tumor necrosis factor-alpha (show TNF Proteins) and interferon-gamma (show IFNG Proteins). Results suggest the existence of an autocrine/paracrine vitamin D system in the neurovascular unit.

  10. CYP2R1 variants had no significant association with serum 25-OHD3 levels among postmenopausal women of the Han ethnic group in Beijing.

Mouse (Murine) Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1) interaction partners

  1. CYP2R1 is the major enzyme responsible for 25-hydroxylation of vitamin D.

  2. Data show that the absence of either of the two key hydroxylases, vitamin D 25-hydroxylase (CYP2R1) or vitamin D 25-hydroxyvitamin D-1alpha-hydroxylase (CYP27B1 (show CYP27B1 Proteins))neither inhibits nor enhances the development of experimental autoimmune encephalomyelitis (EAE).

  3. CYP2R1 is a strong candidate for the microsomal vitamin D 25-hydroxylase.

Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1) Protein Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency.

Gene names and symbols associated with CYP2R1

  • cytochrome P450, family 2, subfamily R, polypeptide 1 (CYP2R1)
  • similar to cytochrome P450 2R1 (LOC563369)
  • cytochrome P450, family 2, subfamily R, polypeptide 1 (cyp2r1)
  • cytochrome P450, family 2, subfamily r, polypeptide 1 (Cyp2r1)

Protein level used designations for CYP2R1

cytochrome P450, family 2, subfamily R, polypeptide 1 , vitamin D 25-hydroxylase , similar to cytochrome P450 2R1 , cytochrome P450 2R1 , cytochrome P450, family 2, R1 , cytochrome P450, 2r1

GENE ID SPECIES
423065 Gallus gallus
541302 Bos taurus
563369 Danio rerio
698834 Macaca mulatta
100127674 Xenopus (Silurana) tropicalis
120227 Homo sapiens
244209 Mus musculus
612993 Canis lupus familiaris
100124375 Sus scrofa
361631 Rattus norvegicus
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